Breast cancer is one of the malignant tumors with a high incidence in my country, and chemotherapy is still an effective treatment for most patients. But in the course of chemotherapy, chemotherapy drugs will inevitably produce some adverse reactions, such as decreased appetite, fatigue, numbness of hands and feet and other symptoms, which affect the quality of life of patients and even affect the clinical treatment effect.
Therefore, out of health considerations, many Miyou think that they need to add more nutrients. In addition to the normal diet, will choose to take additional vitamin supplements.
Can breast cancer patients be supplemented with antioxidants to prevent cancer? Can I benefit from taking vitamin supplements? Below we will list some common vitamin supplements, indicate their relationship with cancer, and help you analyze whether you should eat or not, and how to eat healthy.
Research on various vitamins in suppressing cancer
1. Vitamin C
Vitamin C (hereinafter referred to as VC) has been controversial for many years. According to the research report of "Translational Medicine" under "Science", high-dose VC (non-oral) can regulate the infiltration of immune cells into the tumor microenvironment and inhibit tumor growth through T lymphocytes.
However, studies have also conducted studies on the pharmacokinetics of different administration routes of VC and found that no matter how much VC is taken, the body cannot show anti-tumor activity. Therefore, it shows that intravenous administration of VC has anti-cancer effects. Vitamin Vitamin C cannot achieve the purpose of anti-tumor in the body.
2. Folic acid
Like vitamin C, there are obviously many controversies in the research on cancer suppression.
For example, on January 15, 2019, the research report of the European Journal of Clinical Nutrition under the British "Nature" showed that more folic acid intake may reduce premenopausal breast cancer, estrogen receptor-negative breast cancer, and dual hormone exposure. The risk of breast cancer in women with body-negative breast cancer and high alcohol intake.
However, certain animal studies have also found that large amounts of folic acid supplementation may increase the risk of breast cancer. Due to concerns about the increased risk of cancer, currently does not have enough evidence that folic acid can really fight cancer.
3. Vitamin B3
Vitamin B3 is an indispensable nutrient in the human body. It plays an important role in promoting the normal development of the human body. In addition, it can also promote iron absorption and blood cell production, maintain normal skin function and secretion of digestive glands.
According to data, in animal experiments, it is found that the lack of vitamin B3 can lead to delayed DNA excision and repair, accumulation of single-strand and double-strand breaks, cell cycle arrest and damage to apoptosis, and increase the susceptibility to cancer development. The study believes that vitamin B3 is important for genome stability and may reduce cancer risk.
4. Deep-sea fish oil omega-3 fatty acids
"Clinical & Experimental Metastasis" (Clinical & Experimental Metastasis) published in a study showed that: fish oil omega-3 fatty acids may inhibit the growth and spread of breast cancer cells in mice.
However, the researchers also said that the study emphasizes the potential therapeutic role of dietary long-chain omega-3 fatty acids in controlling tumor growth and metastasis. This does not mean that the omega-3 diet can immediately prevent breast cancer tumor formation. . These are basically some vitamin supplements that everyone often eats (vitamin C tablets, vitamin B tablets, vitamin E soft capsules, deep-sea fish oil omega-3, etc.). Seeing these research results, we should feel happy, after all It's another great progress for the benefit of mankind.
However, comparing these studies, we also found that these experimental results of obviously lack clinical evidence of real hammer.
Image source: Photograph.com
Remember the study of the "Queen of Herbs" Dandelion we mentioned before? "Queen of Herbs" Dandelion soaks in water, can it really fight breast cancer?
Any drug effect out of the dose to talk about effectiveness and toxicity is itself a kind of shame, including the research of vitamins, and the interpretation of any laboratory test results cannot be separated from the clinical background.
Obviously, these studies are still in laboratory studies and animal model studies, and only a few have developed to the stage of human trials. However, there is no very convincing conclusion to say that vitamins can suppress cancer.
"healthy friends" may be the invisible "health killer"?
Seeing this, maybe you may not think that you can fight cancer by eating this stuff, but you always feel that during the recovery period, malnutrition will inevitably occur. It is always correct to make up for it. With this consensus, many cancer friends have started to take vitamin supplements, so that they completely ignore the terrible fact that any nutrient will increase the risk of cancer.
According to a 20-year study involving 50,000 people published in the Journal of the National Cancer Institute, patients with certain genotypes have breast cancer, lung cancer, uterine cancer, and lymphoma leukemia after vitamin E supplementation. It levitated. A recent study published in the Journal of Clinical Oncology also showed that antioxidants (vitamins A, C and E; carotenoids; coenzyme Q10), vitamin B12, iron, and omega-3 are used between breast cancer chemotherapy Fatty acids may increase the risk of relapse and death in patients. The American Association for Cancer Research (AICR), which has an international authoritative guideline, also clearly stated in the "Diet, Nutrition, and Exercise Anti-Cancer Guidelines (Third Edition)": eating high-dose β-carotene supplements will increase lung cancer Risk (in current and past smokers). Image source of
: Photograph.com
As the saying goes, things must be reversed, and nothing is wrong. According to meta-analysis, nutrient supplements cannot reduce malignant tumor-related mortality, nor can it reduce the risk of malignant tumor recurrence. Z5z vitamin supplements are just a way to help people who cannot get enough nutrients from food to obtain nutrition.
Regarding vitamins, breast cancer patients can get them from food without taking additional nutrient supplements. Once taken in large quantities for a long period of time, they will cause symptoms of poisoning, such as hair loss, nausea and vomiting, and loss of appetite. How can
prevent vitamin supplements from becoming "invisible killers"?
Vitamins are a type of nutrient essential for the maintenance of human health. During chemotherapy and radiotherapy, antioxidants (including vitamin C, vitamin E, carotenoids, etc.) may have a potential "repairing effect" on cancer cells.
More and more evidence shows that when the human body has sufficient nutrients, taking nutrient supplements is not only not beneficial, but may cause health damage. In addition, if you take other drugs at the same time, there may be interactions that affect the efficacy of the drugs. Image source: Photograph.com
For example, there is a theory that the mechanism of chemotherapy killing tumor cells is to produce a large amount of active oxygen, but some vitamins are anti-oxidant, which reduces the efficacy of the drug and affects the therapeutic effect. But whether this is true or not, the reasons for this need to be further studied.
According to current research evidence, breast cancer patients should not take a large number of vitamin supplements containing antioxidants during treatment. When does
need to be taken extra? Only after a doctor has diagnosed a nutrient deficiency, do you need to take the necessary nutrient supplements. In other words, if you have a vitamin deficiency, you can consult a nutritionist for additional nutritional supplements.
In short, whether it is cancer patients or ordinary people, vitamins, as an indispensable substance in the human body, are harmful to human health when they are ingested too much or not.
For those who are still in the recovery period, it’s not that you can’t take these vitamin supplements, but that most patients don’t need to take them. The vitamins needed by the body can be met in a normal diet. If you still think about it Supplement more vitamins, may wish to eat more leafy vegetables and fruits, after all, they are the best source! Cover image source of
: Photograph.com Genuine Gallery
Editor: Breast Cancer Mutual Helper
Reference:
[1]Shi Yongmei. Folic acid, vitamin B_(12) and B)6 supplementation to prevent breast cancer[J] .Chinese Journal of Clinical Nutrition,2003(03):73-75.
[2]Liang Zhen, Tan Qixing, Lian Bin, Wei Changyuan, Qin Qinghong, Huang Zhen. The relationship between nutritional status and adverse reactions of chemotherapy in patients with postoperative adjuvant chemotherapy for breast cancer[ J].Chinese Journal of Cancer Prevention and Treatment,2018,10(03):177-181.
[3]Wang Qingmei,Xu Qianzi,Wei Anyi,Chen Shishuo,Zhang Chong,Zeng Linghui.High-dose vitamin C inhibits breast cancer cell proliferation by reducing glycolysis and protein synthesis[J].Journal of Zhejiang University (Medicine Edition),2019,48(03):296- 302.
[4]Yu Kang,Li Zengning,Cong Minghua,Fang Yu,Zhang Pianhong,Li Rongrong,Li Chunwei,Cui Min,Ying Jie.Expert consensus on nutritional management of patients with malignant tumors during rehabilitation[J].Journal of Nutrition,2017,39 (04):321-326.
"medicinal failure"? During the medication, eating these foods is more terrible than not eating them! How can
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