Our team has compiled the information of patients with chronic infection of Helicobacter pylori who were diagnosed, treated and followed up in the comprehensive outpatient clinic of Shangrao Second People's Hospital in the past decade (2011-2021). The number of cases with relatively complete data was 4,982, and the proportion of eradication of the first treatment was about 91.63% (excluding patients who took irregular medication). There are indeed patients who have been repeatedly eradicated for 6 times and are still positive.
Long-term treatment of chronic Helicobacter pylori infections, and long-term follow-up of these patients, we have both successful experiences and lessons from failure. The following eradication schemes are commonly used by us. If you refer to these schemes, you can also become a master in eradicating Helicobacter pylori.
1. Chronic infection of Helicobacter pylori is the main cause of gastric cancer , gastric ulcer bleeding, atrophic gastritis , and the harm is also...
China is a country with high infection rate for chronic infection of Helicobacter pylori, and the estimated chronic infection rate in adults is 45%~~55%. Chronic infection of Helicobacter pylori is an important cause of chronic active gastritis and peptic ulcers , and is the main cause of gastric MALT lymphoma.
China is a country with high incidence of gastric cancer in the world. The chronic infection of Helicobacter pylori and genetic factors, environmental factors, and other pathogenic factors (smoking, drinking, eating barbecue, etc.) have been superimposed and interacted with each other, which ultimately led to the occurrence of gastric cancer. A large number of long-term clinical studies have shown that after eradicating Helicobacter pylori, the incidence of gastric cancer in both Eastern and Westerners can be significantly reduced. Eradicating Helicobacter pylori before atrophic gastritis can almost completely avoid the occurrence of intestinal gastric cancer. It can be seen from this that not only should Helicobacter pylori be eradicated, but Helicobacter pylori be eradicated as soon as possible!
Chronic infection of Helicobacter pylori is also related to many parenteral diseases: 1. Refractory or unknown iron deficiency anemia ; 2. Immune thrombocytopenic purpura in adults; 3. Vitamin B12 deficiency can be caused by some infected people; 4. It has a certain correlation with the occurrence of some skin diseases, such as allergic purpura , urticaria, rosacea , psoriasis, etc.;
5, may be
5, may be
5, 2 Risk factors for the incidence and death of in coronary heart disease; 6. It may be related to the occurrence and development of many autoimmune diseases , such as Sjogren's syndrome , autoimmune thyroid disease, autoimmune liver disease , etc.; 7. Chronic infection of Helicobacter pylori may be related to infertility ...
2. Two-pair drug regimen for eradicating Helicobacter pylori
A, esomeprazole 20 mg/pill, three times a day, one pill at a time, take before meals;
amoxicillin 3 times a day, 1000 mg once, take after meals; two-pill drug, take for 14 days;
B, esomeprazole 20 mg/pill, three times a day, one pill at a time, take before meals;
furazolidone , 0.1g/pill, two times a day, one pill at a time, take for morning and after dinner; two-pill drug, take for 14 days. This regimen is for use by patients with penicillin allergies.
C, Vonola fumarate tablets 20mg/tablet, twice a day, one tablet at a time, before dinner;
amoxicillin 1000 mg three times a day, 1000 mg once, taken after meals; two pairs of drugs, taken for 14 days;
D, Vonola fumarate tablets 20mg/tablet, twice a day, one tablet at a time, taken before dinner;
furazolidone, 0.1g/tablet, twice a day, one tablet at a time, taken after dinner; two pairs of drugs, taken for 14 days. This regimen is for use by patients with penicillin allergies.
((Without esomeprazole, you can also use omeprazole or rabeprazole . The usage and dosage of the two combinations of drugs can vary according to the patient's liver and kidney function status, weight, etc., such as the elderly, light weight, liver and kidney function, etc., which can be used twice.If you are allergic to amoxicillin and furazolidone, we have two other combination eradication plans, and it is recommended to consult and discuss in person)
3. triple
A, esomeprazole 20 mg/pill, twice a day, one pill at a time, take before meals;
bismuth potassium citrate 0.3 g/pill (equivalent to 110 mg of bismuth agent) 2 pills before breakfast
two pills before dinner
two pills before dinner
two pills before dinner
two pills a day, 1,000 mg once, take after morning and after dinner; triple drugs, take 14 days
B, esomeprazole 20 mg/pill, twice a day, One pill at a time, take before morning and dinner;
bismuth potassium citrate 0.3 g/pill (equivalent to 110 mg of bismuth agent) Two pills before breakfast,
two pills before dinner;
furazolidone, 0.1 g/pill, twice a day, one pill at a time, take early and after dinner; triple medication, take for 14 days. This regimen is for use by patients with penicillin allergies.
C, vonola fumarate tablets 20mg/tablet, twice a day, one tablet at a time, before morning and before dinner;
bismuth potassium citrate 0.3g/pillar (equivalent to 110mg of bismuth agent) Two pills before breakfast and two pills before dinner;
amoxicillin 1000mg twice a day, 1000mg of morning and after dinner; triple medication, use 14 consecutive days
D, vonola fumarate tablets 20mg/tablet, twice a day, one tablet at a time, before morning and dinner;
00mg/tablet of bismuth potassium citrate 0.3g/pillar (equivalent to 110mg of bismuth agent) Two pills before breakfast and two pills before dinner;
furazolidone, 0.1g/tablet, twice a day, one pill at a time, take after morning and dinner; triple medication, take for 14 days.
4. Quadruple-linked scheme for eradicating Helicobacter pylori
A, esomeprazole 20 mg/pill, twice a day, one pill at a time, taken before breakfast and before dinner;
bismuth potassium citrate 0.3 g/pill (equivalent to 110 mg of bismuth agent) Two pills before breakfast and two pills before dinner;
amoxicillin twice a day, 1000 mg once, taken after breakfast and after dinner;
furazolidone, 0.1 g/pill, twice a day, one pill at a time, taken after breakfast and after dinner; quadruple-linked medication, taken for 14 days.
B, esomeprazole 20 mg/pill, twice a day, one pill at a time, take it before dinner;
bismuth potassium citrate 0.3 g/pill (equivalent to 110 mg of bismuth agent) Two pills before breakfast and two pills before dinner;
doxylcycline tablets 0.1 g/pill, twice a day, one pill at a time, take it after dinner;
furazolidone, 0.1 g/pill, twice a day, one pill at a time, take it after dinner; quadruple medication, take it for 14 days. This regimen is for use by patients with penicillin allergies.
C, esomeprazole 20 mg/pill, twice a day, one pill at a time, take before morning and dinner;
amoxicillin 0.3 g/pill (equivalent to 110 mg of bismuth agent) Two pills before breakfast and two pills before dinner;
doxiccycline tablets 0.1 g/pill twice a day, one pill at a time, take after morning and dinner;
amoxicillin 1000 mg twice a day, take after morning and dinner;
four-pill drug, take for 14 consecutive days.
(Note: Without esomeprazole, omeprazole or rabeprazole can be used. You can definitely switch to vonora fumarate tablets, which is more expensive.)
5. After eradicating Helicobacter pylori, we routinely recommend taking these drugs
0 After taking the above drugs, some patients will experience digestive dysfunction, such as constipation. It is recommended to take drugs that moisten the intestines and laxative , and combine them with probiotic drugs.
Disable the use of appealed drugs for at least one month. We generally recommend that you check the C13 breath test after two months of quitting the drug to determine the effectiveness of eradication treatment.
Eradicate Helicobacter pylori and stay away from gastritis; eradicate Helicobacter pylori and stay away from the threat of gastric cancer.
I wish everyone has a good stomach!
Jiangxi Province Shangrao Second People's Hospital Comprehensive Outpatient Department Wang Chunxi
