In modern society, with the improvement of people's living standards, material life is becoming more and more abundant, and people are paying more and more attention to physical health. Especially the young people born in the 80s and 90s may pay more attention to health care and health preservation than the people in the past. With the explosion of Internet information, there will also be many popular science articles on the Internet to popularize and introduce chronic diseases.
These articles often mention a point of view: high blood viscosity can form thrombus, leading to cardiovascular and cerebrovascular diseases. A Mr. Wang I know detected an increase in blood viscosity during the physical examination. He heard that aspirin can reduce blood viscosity and prevent thrombosis , so he came to ask me. So should I take aspirin for high blood viscosity?
Should I take aspirin if the blood viscosity is high?
is not necessarily, the reasons are as follows:
1) High blood viscosity does not necessarily lead to thrombosis
Thrombosis is a multi-factor participation in the complex physiological process, blood vessel coagulation and fibrinolysis are the same A state of equilibrium. At present, it is believed that most of the thrombosis often mentioned outside is due to the rupture of atherosclerotic plaque and surface damage. The basal collagen and microfibers under the vascular intima are exposed, causing platelet adhesion, aggregation and activation of the coagulation system. During the development of heart disease, the activity of coagulation increased, and the fibrinolytic activity decreased. That is to say, for thrombosis, high blood viscosity is one aspect, but also the formation of arterial plaque caused by damage to the blood vessel surface.
If it is a smooth and complete blood vessel, even if the blood viscosity of increases , thrombosis will not occur. And in medicine, blood viscosity is also related to many factors, not just thrombosis, such as dehydration, hyperlipidemia, abnormal fibrinogen, elevated blood cells, etc., will cause blood viscosity to increase.If you sweat a lot and drink less water the day before the physical examination, the blood viscosity may increase due to blood concentration. Therefore, the risk of thrombosis cannot be judged by just looking at this item. Strong13strong also needs to evaluate other high-risk factors, such as high blood pressure, hyperlipidemia , diabetes and so on.
2) Aspirin does not reduce blood viscosity
Aspirin is one of the drugs for the prevention of cerebrovascular diseases, but aspirin does not reduce blood viscosity. The reason why aspirin prevents myocardial infarction, cerebral infarction and other diseases is because it is a platelet cyclooxygenase inhibitor, which can inhibit the conversion of arachidonic acid into and prostaglandin and then into TXA2 by inhibiting cox-1. Reduce the occurrence of platelet aggregation to achieve the purpose of reducing thrombosis [2].
In short, aspirin prevents thrombosis by inhibiting platelet aggregation, and does not affect the viscosity of blood. Therefore, it is not right to take aspirin for high blood viscosity, but the reason for the high blood viscosity should be found before processing.
Summary
The human body is a very complicated structure, and we can't take medicine for granted. If there is a problem in the physical examination, you should go to a professional doctor for a systematic assessment, and then choose the appropriate method of prevention and treatment.
References:
[1] Shen Qingle, Zhang Cunqi, Lin Minxi, Li Peiying, Zhou Jianyao. Clinical significance of prethrombotic state and blood viscosity changes in patients with coronary heart disease[J]. Fujian Medical Journal, 2000,03:36- 37.
[2] He Yifan. Research progress on the effect of aspirin on the platelet of [J]. Friends of Health,2018,14:21-22.
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