In obstetrics and gynecology clinics, there are often cases where patients cannot see fetal heart after repeated ultrasound examinations after pregnancy, or when they have fetal heart 2 at the beginning, they find that the fetal heart 2 disappeared after the ultrasound examination.
I was already full of joy and waited for the news that there was a baby
Suddenly, the doctor told his fetus that he had stopped developing
This feeling of loss and pain of gain and loss
is undoubtedly a major blow to a family
usually makes people difficult to accept
Source: Photo Network
Why does this happen? Is there any good way to prevent
?
Then look at
What is "embryo suspension"?
Embryonic urinary As the name suggests, it is the embryo death caused by various adverse factors during the formation process of the embryo.
mostly occurs within 12 weeks of pregnancy (that is, the critical period of the first 3 months) , and its incidence rate accounts for about 10% to 15% of clinical pregnancy [1], which can usually be found during the first or second examination of pregnant women.
Image source: Assisted pregnancy in the center
What are the reasons for the fetal stopping? The causes of fetal discontinuation are very complicated, but the medical community believes that the following factors may be involved:
1 infection factors
1 infection factors
infection is one of the more important factors that cause embryo cessation and development. When the uterine cavity is infected with herpes simplex virus, cytomegalovirus , syphilis chevrons, toxoplasma gondii , etc., it can cause the ovum to stop developing, spontaneous miscarriage , etc. [2].
2 Genetic abnormalities
Genetic abnormalities include chromosomal abnormalities, gene mutations, etc. in both spouses and embryos. In fetal disability, about 80% of pregnant women have chromosomal abnormalities, and some of them will have an increase in incidence as women age [3].
Source: Photo Network
3 Immune factors
During the entire pregnancy, pregnant women will cause alloimmune abnormalities due to various reasons, and their body will reject the intrauterine embryo, which will trigger embryo suspension.
In addition, blood type incompatibility also has a certain correlation with embryo suspension [2] and cannot be ignored.
4 Endocrine Causes
Endocrine-related diseases, such as abnormal thyroid function, corpus luteal insufficiency, polycystic ovary syndrome , etc., will affect the quality of female eggs and the stability of body hormones after embryo implantation.
5 Anatomical factors
If the mother suffers from congenital uterine malformations, reproductive tract malformations, uterine fibroids, etc., it can affect the uterine cavity environment and uterine blood supply, causing the embryo to be unable to grow well, thereby causing fetal suspension.
6 Pre-thrombotic status
Pre-thrombotic status may selectively affect the circulation of the uterus and placenta and lead to microthrombosis in the placenta, ultimately leading to embryonic dysplasia or miscarriage.
7 Environmental factors
In the early stage of development, the embryo is extremely sensitive to the effects of therapeutic drugs and environmental factors. At this stage, various harmful factors can cause damage or even loss of the embryo.
Image source: Center assisted pregnancy
8 Trauma stimulation
The uterus was traumatized before or during pregnancy, such as surgery, direct impact, excessive sexual intercourse, etc. can also lead to fetal suspension or infertility.
9 Male factors
Immaturity of sperm nucleoprotein is one of the male factors that cause the woman to have embryo dissolution. Research shows that husbands are occupational tension and exposure to aromatic hydrocarbon compounds are risk factors for the wife to have embryo dissolution [2].
0 Mental factors
Pregnant women or women of childbearing age have anxiety, depression, pessimism, insomnia and other adverse emotions, which can easily lead to disorders in the body's neuroimmunity and endocrine function, [4], especially changes in progesterone, which can easily lead to embryonic dysplasia and cause fetal stasis. Can
prevent embryo discontinuation in advance?
It’s a pity that during normal pregnancy, it is difficult to intervene artificially. What we can do is to do what we should do within our own abilities.
reduces the risks brought by your own bad living behaviors , and at the same time, it is necessary to correctly screen the causes of embryo discontinuation to reduce the risk of fetal discontinuation again.
Special reminder: The content of this issue has been reviewed by professional doctors. The above popular science content is only for experience exchange. Considering individual differences, if you feel unwell or have acute illness, please go to the offline hospital immediately for treatment!
References:
[1] Wang Hong. Analysis of related factors of embryo suspension and prevention measures [J]. Research on women's health in China and foreign countries. 2020:131-132.
[2] Zhang Xinying, Yang Hua. Analysis of related reasons for embryo suspension [J]. Health of women and children in China and foreign countries. 2011:104-105.
[3] American College of Obstetricians and Gynecologists. AC OG Practice Bulletin No 200: Early Pregnancy Loss. Obstet Gynecol. 2018:197-207.
[4]Xu G Wu Y Yang LRisk factors for early miscarriage am ong Chinese: a hospital-based case-control studyFertil Steril.2014Jun:101(6)1663-70.
