A colleague suffered from diabetes . In the early stage, he insisted on taking traditional Chinese medicine and using dietary regulation, which achieved a good effect of lowering blood sugar, and blood sugar has been controlled within a relatively ideal range. But in recent years, it has not been very good. As he gets older and relaxes his diet regulation, he has to start considering taking medication or choosing insulin .
acarbose under the advice of the doctor. The doctor said that this drug is the "number one" among many antidiabetic drugs. My colleague asked me in confusion, is this acarbose really so magical in the field of lowering blood sugar? What are the wonderful uses for lowering blood sugar?
acarbose is a widely used antidiabetic drug in clinical practice. It is an α-glucosidase inhibitor , and its structure is very similar to that of oligosaccharides. The reason why it can play a good role in lowering glycemic is that this non-oligosaccharide "pseudooligosaccharide" can compete with oligosaccharides at the brush edge of the upper cell intestine.
reversibly binds to α-glucosidase , inhibiting the activities of various α-glucosidases such as maltase , isomaltase, glucose amylase and sucrose , and decomposes starch into oligosaccharides such as maltose ( disaccharide ), maltotriose and dextrin (oligosaccharides), thereby slowing down the decomposition of food into glucose , and slowing down the decomposition of sucrose into glucose and fructose .
Through this series of "slow down" reactions, the absorption of intestinal glucose is slowed down, so as to relieve the increase in postprandial blood sugar and achieve the effect of lowering blood sugar. Judging from the mechanism of lowering blood sugar, acarbose is indeed very good. So which groups of people does this drug mainly apply to?
acarbose has a wide range of indications and is suitable for insulin-dependent or non-insulin-dependent diabetes. It can be used in combination with other hypoglycemic drugs or insulin. Generally speaking, for those with diabetes who already have a lot of experience in using medication, how to use this medication is not difficult.
However, if you are new to this drug, you need to pay attention. The method of taking this drug is the same as other antidiabetic drugs. It has special features. It starts with 25mg, 2 to 3 times a day. Under the guidance of a doctor, you can add the dosage to 50mg after 6 to 8 weeks, 3 times a day.
For acarbose, remember to take the medication time immediately before meals or chew with the first bite of food. In addition, even if the blood sugar control does not meet the standards, you cannot add medicine rashly. The daily amount of acarbose should not exceed 0.3g.
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