text, pictures/Yangcheng Evening News All-Media Reporter Zheng Da Correspondent Jiang Xin
Recently, the ICU team of the Fifth Hospital of CUHK successfully treated a patient with leptospirosis infection and caused multi-organ failure.

In August this year, 68-year-old Mr. Xu went to the emergency department of the Fifth Hospital of the CUHK for treatment due to cough and fever, accompanied by chest tightness and , lower limb fatigue, bilateral thigh muscle aches, and whole body yellow. The examination showed that he had severe lung lesions, obvious shortness of breath, and low oxygenation index. He then went to the infection of ICU for further diagnosis and treatment. During this period, his condition developed rapidly, and he developed symptoms such as acute respiratory failure, acute renal failure, liver failure, and severe reduction of platelets and . Li Chunna, deputy chief physician of the ICU, said that the patient's alveolar lavage fluid was tested by mNGS (technology to deeply and quickly identify infected pathogens without culture) and showed that leptospirosis infection was diagnosed as severe leptoplasmosis.
After nearly a month of active anti-infection, bedside hemofiltration , 3 artificial liver and symptomatic support and other treatments, the patient successfully removed the tracheal intubation and left the ventilator, his liver function returned to normal, and his renal function gradually improved. He has been successfully transferred back to the general ward to continue rehabilitation and treatment.
Leptospirosis is referred to as Leptospirosis , which is an acute animal-derived infectious disease caused by pathogenic Leptospirosis ( Leptospirosis ). Murine and pigs are the main storage hosts and infection sources of . Secondly, dogs, cattle, sheep, horses, etc. can also carry bacteria for a long time and become a potential source of infection. The disease is widely distributed and can occur throughout the year. It is mainly prevalent in summer and autumn, and is mostly caused by farmers, fishermen, slaughter workers, field workers and miners.
This disease is mainly transmitted through direct contact. Animals carrying hook bodies defecate and urine contaminate the surrounding environment, and the virus invades the human body through the skin, especially the broken skin and mucous membranes. For example: when harvesting rice, humans are exposed to epidemic water when encountering floods or heavy rains, and when raising or slaughtering domestic animals, they are exposed to excrement, blood and organs of sick or bacterial livestock. The second is gastrointestinal transmission, eating food and water contaminated by rat urine can also be infected through the oral and esophageal mucosa. There are also reports that infection can be caused by rats and dogs.
Xia Jinyu, director of the Infectious Disease Prevention and Control Center of the Fifth Hospital of Zhongda University, reminds citizens to pay attention to personal protection and try not to fish, swim or play in ponds and ditches to reduce unnecessary contact with the epidemic water; when work needs to be done, they should wear long rubber boots and rubber gloves; livestock feeding places, slaughterhouses, etc. should do a good job in environmental sanitation and disinfection. If you have symptoms such as fever, fatigue, muscle aches, yellow urine, reduced urine volume, chest tightness, shortness of breath or hemoptysis, you should be wary of leptospirosis infection and go to the infection department of a regular hospital in time.
Source | Yangcheng Evening News·Yangchengpai
Editor | Huang Lei
Proofreading | Pan Liling