Recently, a team of scientists from Hong Kong Chinese University and Stanford University in the United States found that fragile psychology such as sadness and loneliness can accelerate aging more than smoking. This means that psychological factors cannot be ignored by any anti-aging method. Related research has been published in the recent journal Aging.
This is really an interesting study. It is concerned with comparing the emotions of that are difficult to quantify and the effects of smoking that are easy to quantify on aging. It turns out that emotions are more likely to make people aging than smoking...
Today I will talk to you about How to measure aging and the impact of psychology and smoking on aging?
1, how to measure aging?
The aging here is not a natural age, but a physiological test. So what is physiological age? For example, we often use the same age Guo Degang and Lin Zhiying as a comparison. The actual aging of the same age is different, that is, the physiological age is different.
Here, the author uses epigenetic method, which is also a relatively mature method, which is to use epigenetic to predict the physiological age of a person.
For example, there was a review in nature that introduced the use of epigenetics to predict physiological age.
There are many studies on this aspect, and many methods have been summarized.
basically detects physiological age by detecting the epigenetics of DNA, mainly DNA methylation , the most common and easiest to detect epigenetics. In this article, the author also has a similar idea.
First used data from the vertical study of health and longevity in China.
Then 16 blood indicators, 7 physiological parameters and indicators were collected, and of course, including biological gender.
is shown in the following figure, which are some indicators.
Next, through the neural network learning, a set of measurement methods was established, that is, aging clock (agging clock) . It seems that this model is quite mathematical
. According to their calculation simulations in the three groups, it was found that this fitting level is not bad. From the age prediction angle, the average absolute error is 5.68 years. The
model has been established, and we started to study it.
2, which one has the greater impact on aging, psychology or smoking?
The data of participants here are shown in the figure below
is mainly divided into psychological influence and daily life (smoking), such as some psychological corresponding options, such as unfortunate (rarely feel happy), rarely fearful, etc.
After entering these data, performing calculations, it is found that different factors have different effects on human aging. For example, it shows differences in related aspects of disease
Finally, it was found that these different states do not have much impact on people.
As can be seen in the figure, poor psychological condition has the most obvious effect on physiological age, 1.65 years old, followed by smoking, 1.25 years old. In addition, if it is a man, this gender itself will make people older more likely. Of course, this has also been widely discovered. Men are more likely to grow older than women, and they die earlier than women. Long-lived elderly people are basically women.
In addition, if you live in rural areas, it will make people older more likely. This is understandable. After all, the living environment, diet, and medical health in rural areas are relatively poor.
Finally, there is still single (never married), which is easy to get old.
This study is normal, but what is interesting is that it quantifies the influence of psychological factors and finds it is more serious than smoking. This is indeed surprising.
So everyone, adjust your mood well and don’t make it all day long.
