first clarifies two concepts, antibiotics and antibacterial drugs. Antibiotics refer to substances produced by certain microorganisms such as bacteria, fungi, actinomycetes, etc., which have anti-pathogen effects. In addition to being extracted from microorganism culture fluids, antibiotics can also be semi-synthetic Method or synthetic method, such as penicillin, cephalosporin, etc. Antibacterial drugs refer to drugs that can inhibit or kill bacteria, including antibiotics and synthetic antibacterial drugs (quinolones, sulfonamides, nitrofurans, nitroimidazoles, etc.). The concept of antibacterial drugs is more extensive, so , Cefixime is both an antibiotic and an antibacterial drug.
Cefixime is the third-generation cephalosporin for oral administration. It is a fast bactericide. It mainly prevents the synthesis of bacterial cell walls and exerts a bactericidal effect. It has a broad antibacterial spectrum, strong bactericidal power, less allergic reactions, and stable to β-lactamase. (Can be used for drug-resistant bacteria) and other advantages, mainly suitable for acute and chronic bronchitis, bronchiectasis with infection, acute exacerbation of chronic obstructive pulmonary disease, pneumonia, scarlet fever, otitis media, sinusitis and other respiratory infections, renal pelvis Urogenital infections such as nephritis, cystitis, and gonococcal urethritis, and biliary tract infections such as cholecystitis and cholangitis. The mechanism of cefixime is to inhibit the synthesis of peptidoglycan in bacterial cell walls, resulting in cell wall defects and continuous entry of water, causing the bacteria to expand, rupture and die. However, the human body has no cell wall. Therefore, cefixime is safe for the human body. Sex, adverse reactions are usually few and mild, suitable for children to take, children can choose cefixime granules or dispersible tablets.
For children, cefixime is a relatively safe antibiotic. Compared with penicillin antibiotics, its structure is more stable, it is not easy to hydrolyze and open the ring to produce impurities, and the incidence of allergic reactions is low, but there is a history of penicillin allergy, bronchial asthma, Children with a history of chronic urticaria should use cefixime with caution. In addition, cefixime is a broad-spectrum antibiotic. Long-term use can disrupt the intestinal microecological balance and cause diarrhea or even severe diarrhea. Children should pay attention to the characteristics of stool during medication. Once loose stools or diarrhea are found, they should be stopped immediately medicine. Finally, cefixime can disrupt the intestinal microecological balance, reduce the synthesis of vitamin K, and easily cause coagulation dysfunction, leading to bleeding. Children should immediately experience bleeding gums, nose bleeding, melena, hematuria, etc. during medication. Stop the medication and seek medical attention. As safety has not been determined, it is not recommended to take cefixime for infants and children under 6 months.
In short, antibacterial drugs include antibiotics. Cefixime is both an antibiotic and an antibacterial drug. It mainly acts on the cell wall of bacteria and has good safety for children. It is best to use granules and dispersible tablets. In clinical practice Suitable for bacterial infectious diseases such as respiratory system, urogenital system, biliary system infection and so on. Cefixime is not easy to cause allergic reactions. Long-term use can cause intestinal flora disorders and blood coagulation dysfunction. The safety of cefixime for infants under 6 months is not clear and it is not recommended.
