When it comes to rare blood type
Everyone will think of RH-negative "panda blood"
But there is also a kind of blood type is more rare than panda blood
is called "dinosaur blood"
that is Mumbai-like
It is reported that this type of blood type was first discovered in Mumbai, India in 1952, and is extremely rare in China.
People with this blood type account for
in the country. The ratio of
is only one in ten thousand
in the country.
is only more than 100 cases in the country. Because this type of "Mumbai-like blood type" is very rare, its value and significance are particularly significant.
event backtracking
Recently, the Laboratory Department (Hematotransfusion Department) of Changsha Fourth Hospital found a Mumbai-like blood type. Not long ago, a minority pregnant mother visited at , Changsha Fourth Hospital. During the diagnosis and treatment of
, deputy chief examiner Liu Qianxi found that the ABO blood type of the pregnant woman did not match the positive and negative typing. The positive typing manifested as O-type characteristics, and the anti-typing manifested as B type characteristics, which was positive for screening but negative for itself.
This abnormal result immediately caused
Her high alert
immediately contacted the pregnant woman to find out the situation
The pregnant woman gave birth to the previous two babies in the hospital, and her blood type was set as O type . Liu Qianxi immediately reported the situation to the department director Zhang Biming, who organized the department to conduct in-depth research on this difficult blood type.
After re-examination of serological experiments such as anti-H, saline anti-sieve method, absorption and dispersion experiment, microcolumn gel method, test tube method, was initially considered as a Mumbai-like blood type.
Source: Changsha Fourth Hospital official WeChat public account
In order to ensure the accuracy of the test results
Zhang Bi Ming led
blood transfusion department personnel to continue to read a large amount of information
and consulted blood transfusion experts inside and outside the province
experts suggested blood type gene testing
Due to the limited testing conditions of the hospital and the actual blood type of pregnant women, after fully communicating with the pregnant woman, Liu Qianxi contacted West China Hospital for free for blood type gene testing for the pregnant woman.
On October 11, final result return:
patients have a serology of Mumbai-like type B. The sequencing results of FUT-1 gene comply with FUT1*01W.37 (weak expression of H antigen) published by the ISBT International Society of Transfusion. The sequencing results are shown as FUT1*01W.37//FUT1*01W.37. The results of ABO gene sequencing are in line with B101/O02 published by the ISBT International Society of Transfusion. The patient's gene expression was normal B glycosyltransferase activity, and the ABO glycosyltransferase gene mutation was excluded to lead to ABO subtype.
Source: Changsha Fourth Hospital Official WeChat Official Account
Source: Changsha Fourth Hospital Official WeChat Official Account
Experts said
General ABO blood type is
Cannot detect Mumbai blood type ,
If no further Check
is easily mistaken for O blood
Zhang Biming, director and chief technician of the Laboratory Department (Hematopoietic Transfusion Department) of Changsha Fourth Hospital, said that people with blood type usually have a pair of regulatory genes ZZ, which partially inhibits the H gene's H antigen formation on red blood cells , but does not affect the synthesis of H substances in saliva. Therefore, H antigen is generally not found on Mumbai-like red blood cells, but only a small amount of A or B antigen. In addition to anti-A and anti-B antibodies, there are also anti-H antibodies in the serum, and A or B antigens can be found in saliva.
The best way to identify blood type in Mumbai is to check whether there is H antigen in the blood, so that it can be accurately detected.
In addition, if this type of population needs blood transfusion, it is difficult for
to find matching blood.
For pregnant women with rare blood types, once
major bleeding or other blood loss occurs during the operation,
will face the dilemma of no blood to be transfusion.
Therefore, in daily life, this type of people should pay special attention to their own health and safety
Warm reminder
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""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm""htm"""htm"""htm"""htm"""htm"""htm"""htm"""htm"""htm"""htm"""htm"""htm""""htm""""htm""""htm"""When emergency blood transfusion is required without the same type or without autologous transfusion, the ABO homotypic blood that does not respond to the patient's serum or the weakest response should be first injected to minimize the risk of hemolysis. During the infusion process, it is necessary to closely observe whether adverse blood transfusion reactions occur to fully ensure that the patient can undergo blood transfusion treatment safely and effectively.
Seeing the news
Many netizens lamented:
"A good doctor regards life as a treasure, is rigorous and responsible"
Some netizens joked
to "protect this mother
like a rare animal
Xiaofang said:
new knowledge has increased
What do you feel about friends?
Welcome to leave a message in the comment area to interact!
Source: News Floor comprehensive from the official WeChat public account of Changsha Fourth Hospital, Changsha TV Politics and Law Channel, FM93 Traffic Voice, Xiaoxiang Morning News, Netizen Comments
Editor: Li Shijing
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