With the development of society and economy, people's lifestyle and dietary structure have changed. The prevalence of hyperuricemia in my country is increasing year by year and is getting younger. It has become the second largest metabolic disease after diabetes . According to reports from various places in recent years, there are currently about 120 million people with hyperuricemia in my country, accounting for about 10% of the total population. The most common age groups are middle-aged and elderly men and postmenopausal women, but in recent years there has been a trend of younger people.
In clinical practice, patients often seek medical treatment because of high uric acid or gout attacks found in physical examinations. However, most patients do not understand the dangers of high uric acid. In terms of diet, they only know to avoid seafood and beer. This article will introduce to you the symptoms of hyperuricemia and gout. Its care.
Hyperuricemia definition
Uric acid is the terminal metabolite of purine compounds in humans. Purine metabolism disorders lead to hyperuricemia. Under a normal purine diet, if the fasting blood uric acid level is higher than 420 μmol/L in men and higher than 360 μmol/L in women twice on different days, it is called hyperuricemia.
Uric acid is produced in the liver from dietary intake and purine compounds decomposed in the body , and is mainly excreted by the kidneys and digestive tract. Under normal circumstances, the production and excretion of uric acid in the body remain balanced. Physiological concentrations of and blood uric acid are effective antioxidants in the extracellular environment, scavenging up to 60% of oxygen free radicals in the human body. Therefore, uric acid should not be reduced too low.
Decreased uric acid excretion or increased production can lead to its increase. When blood uric acid exceeds the saturation concentration, urate crystals precipitate and can be deposited in joints, renal tubules and blood vessels, causing inflammatory damage. Therefore, in addition to gout, high uric acid is also related to the occurrence and development of systemic diseases such as kidneys, endocrine metabolism, cardiovascular and cerebrovascular diseases, and requires attention and timely treatment. Choose personalized treatment plans based on different causes and underlying diseases. In clinical practice, uric acid-lowering drugs, urine alkalinizing drugs and symptomatic treatment of acute gout attacks are commonly used.
Drug Treatment
Traditional Chinese Medicine No matter whether there are clinical symptoms or not, strengthening the spleen, draining turbidity and removing blood stasis is the basic treatment method, which runs through the entire treatment. On the basis of syndrome differentiation and treatment, the selection of prescriptions and medications can also refer to the research results of modern pharmacology and be used as appropriate:
1. Drugs that lower blood uric acid: such as Smilax truncatula, 萆薢, Lily;
2. Dissolve uric acid Drugs: such as clematis , Genie , Polygonum cuspidatum
3. Drugs that excrete uric acid: such as psyllium, Alisma , Coix seed , Dilong;
4. Drugs that inhibit uric acid synthesis: Such as Zelantra , Angelica , Peach kernel ;
5. Drugs that alkalize urine: such as Green peel , tangerine peel, talc , etc.; 6. Drugs that promote the excretion of uric acid from the stool: such as Citrus aurantium , rhubarb , betel nut;
7. Remove local inflammation drugs, such as atractylodes, honeysuckle, and clematis.
In addition, local treatments such as external application of traditional Chinese medicine, fumigation and washing can make the effect of the medicine reach the hospital directly, helping to reduce swelling and relieve pain.
Non-drug treatment
If you find that uric acid is high, you should pay attention to non-drug intervention whether before drug treatment or when taking medicine.
1. Promote a balanced diet, limit total daily calorie intake, and control the purine content in the diet. mainly follows a low-purine diet and strictly limits the intake of high-purine foods such as animal offal, seafood and meat. Purine-rich vegetables, beans and soy products have no significant correlation with hyperuricemia and gout attacks. Patients are encouraged to eat more fresh vegetables and moderate amounts of beans and soy products (people with renal insufficiency must eat under the guidance of a specialist).
2. Drinking plenty of fluids can shorten the duration of gout attacks and reduce symptoms.
People with normal heart and kidney function need to maintain appropriate body moisture, drink plenty of water, and maintain a daily urine output of 2 000 to 3 000 ml. You can drink milk and dairy products, and avoid drinking cola, orange juice, apple juice and other fructose-containing drinks or sugary soft drinks, as well as thick soups.
3. Fruits are rich in potassium and vitamin C, which can reduce the risk of gout attacks.
You can eat fruits containing less fructose, such as cherries, strawberries , pineapples, watermelons, peaches, etc.
4. Alcohol intake should be limited and rice wine, beer and liquor are prohibited. There is controversy over whether red wine increases blood uric acid levels.
5. Obesity increases the risk of gout in patients with hyperuricemia.
6. Moderate exercise is encouraged, and strenuous exercise or sudden cold exposure that may trigger gout attacks should be avoided during exercise.
7． Smoking or passive smoking increases the risk of hyperuricemia and gout. You should quit smoking and avoid passive smoking.
