In the human intestine, hundreds of millions of intestinal bacteria are inhabited, which constitute a complex microbial ecosystem. The key to maintaining health in the human body lies in maintaining a friendly and mutually beneficial "symbiotic relationship" with the microbial ecosystem. "Intestinal bacteria fermentation dietary fiber provides short-chain fatty acids to the host" best reflects this "human-bacterial" symbiosis relationship.
It can be seen that intestinal bacterial flora plays an extremely important role in body health. It will not only affect your immunity, but also extract energy from your food, thereby affecting your metabolism.
At the same time, the microbiota can change according to changes in the surrounding environment. This characteristic also shows that our eating habits are of great significance to the growth of intestinal flora. How does intestinal flora affect diabetes ?
The immune system uses intestinal microbiota to control glucose metabolism. If this metabolism is unbalanced for some reason, it will lead to increased blood sugar, resulting in html type 12 diabetes . Intestinal flora also plays a key role in the continuous treatment of diabetes .
For people with type 2 diabetes, a long-term high-sugar high-fat diet will destroy the diversity of intestinal flora, such as causing abnormal increase in Firmicutes in the intestines and reducing Bacteroidetes , causing the body to absorb too much energy from food and reduce insulin sensitivity. A recent study by
Swedish showed that intestinal microbial disorders can also reduce the effect of first-line treatment drugs for diabetes such as metformin . Studies have found that microorganisms in the intestine interact directly or indirectly with drugs, affecting the efficacy and side effects of drugs, resulting in differences in different individuals' responses to drugs.
Because everyone has different health conditions, the composition of intestinal flora may also be different. Therefore, each person also differs when it comes to regulation of energy metabolism and insulin response. Studies have shown that the microbial composition of diabetic patients and non-diabetic patients is different. This difference may potentially drive the development of diabetes.
Among different people, the peak blood sugar changes after eating are often incredible. A person's unique physiology, genes and intestinal flora are the causes of this change. Currently, researchers can use the algorithm of gut microbiota to predict the post-prandial blood sugar peak of , which may be more accurate than the carbohydrate counting method.
Therefore, by improving the dietary structure, combining intestinal microbiota adjustment, and increasing the abundance of probiotics, it is of great help to control blood sugar in diabetic patients. It can be said that intestinal microbiota regulation is a link that cannot be ignored in the process of diabetes management.