This article is original from Translational Medicine Network. Please indicate the source when reprinting
Author: Jevin
Introduction: The broad understanding is: tall people often achieve a healthy state after obtaining more nutrition, but is the fact really as we imagined?
Recently, Researcher from Johns Hopkins University in the United States published a research paper in "Cancer Epidemiology, Biomarkers Prevention" , the journal . Studies have shown that the higher the height, the greater the risk of cancer.
https://pubmed.ncbi.nlm.nih.gov/35247904/
Previous studies
01
In the 1950s, Dr. Emelie Benyi from Karolinska Academy , Swedish, a study of more than 35 million Swedish men and women showed that the higher the height, the greater the risk of cancer.
Doctor of Cancer Biology at Duke University in the United States Li Zhizhong also introduced the research on "height and cancer risk" in detail in his book. confirmed that "the higher the height, the more likely it is to get cancer." Combined with the risk of multiple cancers, for every 4 inches increase in height in adults, the risk of cancer in women increases by 18% and for men 11%. The study report says taller women have a 20% higher risk of developing breast cancer . The researchers say that for every 4 inches increase in height, the risk of melanoma increases by 30%.
Korean scholars have published a study on height and cancer risk. From 2009 to 2012, a total of 22,809,722 observation subjects older than 20 years old were included in the study. The researchers collected and analyzed the characteristics of these subjects until 2015. During the 5-year follow-up period, 765,651 patients were diagnosed with cancer. The higher the height of the subjects observed in the study, the greater the risk of cancer, and in contrast, the overall risk of cancer among tall people increased by 28%.
Researchers from Harvard School of Public Health have also conducted research on the relationship between height and cancer risk. She believes that: Adult height is related to the size of organs. The higher the height, the larger the body's organs, the larger the volume of the organs of people, so the higher the height, the more active the proliferation of cells in the organs of people with higher heights, the greater the possibility of mutations, and therefore the more likely it is to induce cancer.
Height and risk of colorectal cancer
02
Recently, Researcher from Johns Hopkins University in the United States published a research paper in the journal of the American Cancer Research Association. This is the largest study of the same kind to date . During physical examination or screening, higher height is likely to be a neglected cancer risk factor. Therefore, height should be considered a risk factor for colorectal cancer screening .
In this study, researchers analyzed data from 47 observational study , involving 280,660 colorectal cancer and 14,139 colorectal adenoma cases. 33 of these studies reported data on the incidence of colorectal cancer for every 10 cm increase in height, 26 studies compared the incidence of colorectal cancer among individuals with the highest and lowest heights, and 4 studies reported data on assessing the incidence of colorectal adenomas for every 10 cm increase in height. The study recruited 1,459 adult patients undergoing outpatient colonoscopy to explore the relationship between cancer and bacteria that adhere to the colon wall. Data analysis found that the highest person has a 24% higher risk of colorectal cancer than the lowest, with a 14% higher risk of colorectal cancer for every 10 cm increase in height and a 6% higher risk of adenoma.
Research significance
03
According to the statistics of the National Cancer Center in 2021, my country's colorectal cancer incidence ranks second in malignant tumors and fourth in mortality rate. , and since 2000-2016, the incidence and mortality rate of colorectal cancer have shown an upward trend. For colorectal cancer, there are some well-known variable dietary factors such as processed red meat and smoking, and height is often overlooked clinically during screening. Therefore, the researchers say height should be considered a risk factor for colorectal cancer screening.
and results show that the risk of almost all cancer types increases with height . This study compared 17 common cancer types in women, among which 15 common cancers all increased in incidence. Among them, the most risky ones include breast cancer (increase 17%), colorectal cancer (increase 25%), leukemia (increase 26%), renal cancer (increase 29%) and other .
Reference materials:
https://pubmed.ncbi.nlm.nih.gov/35247904/
Note: This article aims to introduce the progress of medical research and cannot be used as a reference for treatment plans. If you need health guidance, please go to a regular hospital for treatment.
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