Recently, "IBT Border Technology", a brain science smart medical company focusing on mental health services for children and adolescents, held an academic conference in Chengdu with the theme of "The Application of Digital Therapy in Children's Mental and Mental Diseases".
This academic conference invited Professor Huang Yi of the Mental Health Center of Sichuan University West China Hospital , Professor Xue Gui, Professor of the National Key Laboratory of Cognitive Neuroscience and Learning at Beijing Normal University and Chief Scientific Advisor of IBT Wujiang Technology, Professor Zhou Hui of the West China Second Hospital of Sichuan University, Professor Ouyang Xuwei, Director of Chengdu Fourth People's Hospital , and Associate Researcher Zhao Weihua of the School of Life Sciences and Technology of the University of Electronic Science and Technology as the main speakers, focusing on the digital treatment of children's mental and mental illnesses to discuss, and sharing knowledge with the entire network through online live broadcast.
Copy the link below to the browser to watch the full version of live playback~
https://apprpinb0mi3830.h5.xiaoeknow.com/v2/course/alive/l_6307186ae4b0eca59c27b890?app_id=apprpinb0mi3830&alive_mode=0&pro_id=&ty pe=2&state=6afb26b83fd32919e97ef0ef044c6ded_MnCjmz
Professor Huang Yi
ADHD standardized treatment, digital therapy cognitive training plays an important role in non-drug treatment
▲ Professor Huang Yi Professor
Professor Huang Yi introduced that the core symptoms of ADHD mainly include the dimension of inattention and hyperactivity impulse, which are closely related to impaired brain executive function. Speaking of ADHD intervention, Professor Huang Yi said that children of different ages should adopt different intervention methods. Preschool children advocate behavioral intervention, and behavioral intervention includes non-pharmaceutical means such as parental training and cognitive training; school-age children need to adopt behavioral intervention, and moderate to severe need to be combined with drug treatment. How to improve compliance with non-drug treatments? Professor Huang Yi said that its convenience is very important, such as whether children need to go to the hospital frequently and take a long time, etc. In the long run, digital therapy cognitive training will be a good choice in improving treatment compliance.
Professor Huang Yi also mentioned that about 69% of ADHD children suffer from more than one mental disorder, such as oppositional defiance disorder, anxiety/depression, etc. Experts agree that the task behavioral problems and emotional control problems are not effective through drug intervention, and it is recommended to use cognitive behavioral intervention. Inhibition and control training in cognitive ability is a feasible intervention method for emotional problems, but insufficient professional staff is a major difficulty facing you. Professor Huang Yi said that currently multimodal intervention with drug therapy combined with behavioral training is the most effective intervention solution for ADHD.
Professor Xue Gui
reveals the cognitive basis and neural mechanism of executive function, and digital therapy provides important value for clinical applications
▲Professor Xue Gui National Key Laboratory of Cognitive Neuroscience and Learning of Beijing Normal University
Professor Xue Gui introduced that digital therapy has the advantages of strong therapeutic targeting, long-lasting prognosis effect and small safety side effects, and the principle of cognitive neuroscience is based on the theory of brain functional partitioning and the principle of brain plasticity. The core of digital therapy is to find the precise targets of the brain area involved in the patient's symptoms, better improve the plasticity of the brain and the migration of training, and carry out targeted cognitive training and behavioral interventions to improve and enhance brain function, thereby alleviating symptoms.
Execution function is a complex cognitive structure, mainly including three components: inhibition control, update and switching. It reveals the structural model of the executive function through cognitive neurogenetic methods. The "cold" executive function closely related to inhibitory control, switching, and renewal mainly plays a role in the dorsolateral prefrontal cortex and ventromedial prefrontal lobe, while the "hot" executive function related to emotional control mainly relies on the medial prefrontal lobe to play a role.
Speaking of the application of digital therapy in auxiliary diagnosis, Professor Xue Gui said: Currently, in clinical practice, the diagnosis of mental and psychological diseases is mainly based on scales. There are individual differences in the way of self-evaluation or other evaluation, which will affect the results of the assessment. The medical-grade " Eight Views Cognitive Assessment System" is being built by "IBT Wuwang Technology", which is based on brain functional network partitioning, applies digital therapy to the diagnostic system in the field of objective cognition, integrates traditional cognitive evaluation scales, and adds new research technology to achieve the diagnosis of diseases.
Digital therapy has many benefits, but it also faces some challenges, including how to improve the targeted, efficient and migratory nature of digital therapy. "IBT Borderless Technology" has now established a comprehensive and rich module to formulate personalized and efficient training, namely an adaptive digital training system, for the different cognitive impairments of each ADHD child, so as to achieve the purpose of more efficient and precise intervention.
Speaking of the outlook for digital therapy, Professor Xue Gui hopes to achieve further development of the comprehensive treatment model through cooperation between hospitals, families and schools, effectively combine symptom management, cognitive training and lifestyle, and based on Internet + artificial intelligence technology and real-world big data collection, form a comprehensive intervention method that opens up the closed loop of doctors, parents and teachers.
Director Ouyang Xuwei
New technology for children's psychological Development and cognitive function evaluation
▲ Ouyang Xuwei Director Chengdu Fourth People's Hospital
Director Ouyang Xuwei introduced the relationship between cognitive function and intelligence through multiple cases. However, at present, children's cognitive development assessment is mostly conducted only through intellectual assessment. Director Ouyang Xuwei revealed in detail the new technology of children's psychological development and cognitive function assessment - the methods and principles of psychological evaluation, including visual perception -movement integration test, attention, memory, etc. Director Ouyang Xuwei pointed out that compared with intellectual assessment, accurate and multi-dimensional psychological assessment, the test results can not only reveal children's cognitive abilities, but also highly sensitive to brain dysfunction.
Director Ouyang Xuwei expressed the importance of accurate and multi-dimensional psychological assessment in disease diagnosis and treatment through case discussions, and it needs to involve assessment areas such as social maturity and social activities. Director Ouyang Xuwei also proposed the ideas and processes of digital cognitive evaluation, including behavioral data and observation interviews, which provided important insights for the development of digital therapy.
Associate Researcher Zhao Weihua
ASD treatment plan, digital treatment is expected to improve the symptoms of autism
▲ Zhao Weihua Associate Researcher
Associate Researcher Zhao Weihua summarized the intervention methods of autism spectrum disorder (ASD, referred to as autism) and introduced the research progress on autism in his laboratory. Currently, the incidence of ASD in China has reached 0.7%, and its intervention methods mainly include drug intervention, behavioral intervention and digital treatment, but the effects of drug intervention and behavioral intervention are not ideal. At present, his research group mainly focuses on the impact of oxytocin and digital intervention on autistic children. Associate Researcher Zhao Weihua introduced that previous studies have shown that oxytocin enhances the social functions of children with autistic children. His research group optimized the intervention plan and found that nasal oxytocin enhances the social functions of children with autistic children, and explored the effect of oxytocin on different subtypes of autistics. In addition, Associate Researcher Zhao Weihua and his research group discovered that taVNS stimulating the vagus nerve in the ear promotes social processing of faces.
At present, the research team of associate researcher Zhao Weihua has carried out scientific research cooperation with "IBT Borderless Technology" in the field of digital therapy, and the two sides jointly explore the impact of emotion recognition training on the social function of autism. Associate Researcher Zhao Weihua said that the research team will further explore the effects of oxytocin, taVNS, massage therapy and digital therapy as autism treatment methods.
round table discussion
Frontier scientific research achievements and digital technology serve clinical diagnosis and treatment
In the round table discussion session, Professor Huang Yi, Professor Zhou Hui and Professor Xue Gui discussed the transformation and application of digital therapy in clinical practice respectively.
Professor Huang Yi strongly supports scientific research in the exploration of diseases and proposes how clinicians should cooperate with scientists to apply scientific research to clinical diagnosis and treatment in the early stage, and how to accurately locate ADHD-related executive functions for training, which can more effectively improve the effect of migration. Professor Huang Yi said that there is hope to find the relationship between executive function and clinical symptoms, further serve the diagnosis and treatment of the disease, and to deeply explore the necessity of "hot" executive function in children with ADHD.
Professor Zhou Hui expressed his affirmation of the importance of precise clinical evaluation. When talking about whether there are differences in cognitive training in children with different subtypes of diseases, Professor Zhou Hui said that he will continue to pay attention to the generalization effect of cognitive training.
Professor Xue Gui introduced the development of digital therapy and said that more and more in-depth work is needed to further reveal the mechanisms of the disease. Accurate assessment is a challenge facing us at present. Scientific research needs to work closely with clinical practice to obtain more data and further explore with advanced technology to achieve personalized treatment.
