Among the clinical symptoms of Parkinson's disease , non-motor symptoms should not be underestimated. Poor sleep, bad mood, poor sense of smell, etc. will seriously affect the patient's quality of life. How should we respond when emotional warning occurs?
Pay attention to the problem of depression/anxiety
It is not uncommon for Parkinson's disease to be accompanied by depression, about 35%, and Parkinson's disease is accompanied by anxiety, about 31%. Depression/anxiety will lead to poor mood, reduced quality of life, and poor exercise in patients with Parkinson's disease. Combined with poor functioning and depression, motor function declines faster.
What are the symptoms of emotional problems in patients with Parkinson's disease?
Low mood, inattention, fatigue, constant anxiety, etc.;
If you want to judge whether you have the possibility of depression
just ask yourself two simple questions:
1. In the past two weeks, have you been depressed or depressed? despair?
2. In the past two weeks, have you felt that you have lost interest in doing things?
If the answer to any of the above questions is "yes"
you need to further check whether you have depression.
What should I do if I have depression/anxiety?
- l Exercise training improves depression and anxiety : such as aerobics , Tai Chi , jogging, etc., which can be 20-30 minutes each time, not more than 2 hours a day, at least 3-4 times a week. If possible, several people can do exercise training together in a group with music, which will help improve your mood.
- l Positive psychological intervention, seek help from a psychologist 1.
- When depression affects daily life, consider adding antidepressant drugs to treat under the guidance of a doctor.
- It would be great if there were drugs that could improve both motor symptoms and depression of Parkinson's disease : Monoamine oxidase type B inhibitors, dopamine receptor agonists can improve both motor symptoms and depression symptoms of Parkinson's disease, Kill two birds with one stone. (Please follow your doctor’s advice when taking medication).
- Be careful when using certain anti-Parkinson's drugs, which may cause psychiatric symptoms: hallucinations and delusions, impulse control disorder (unable to control one's impulses), etc., such as dopamine receptor agonists, anticholinergics and amantadine 1. If mental symptoms occur, be sure to seek medical attention promptly (please follow your doctor’s advice when taking medication).
Non-motor symptoms in patients with Parkinson's disease, especially depression/anxiety, and sleep disturbances.It is an important factor affecting the quality of life of patients. Only when the mood is good, the quality of life will be really good!
References:
Parkinson's Disease and Movement Disorders Group of the Neurology Branch of the Chinese Medical Association, Parkinson's Disease and Movement Disorders Group of the Neurology Branch of the Chinese Medical Doctor Association. Chinese Parkinson's Disease Treatment Guidelines (Fourth Edition) [J] . Chinese Journal of Neurology, 2020, 53(12): 973-986.
Chen Shengdi, Wu Li. Pay close attention to the early identification and treatment of non-motor symptoms of Parkinson's disease [J]. Chinese Journal of Modern Neurological Diseases, 2013, 13( 8):653-655.
Qin Z, Zhang L, Sun F, Liu H, Fang X, Chan P; Chinese Parkinson Study Group. Depressive symptoms impacting on health-related quality of life in early Parkinson's disease: results from Chinese L- dopa exposed cohort. Clin Neurol Neurosurg. 2009 Nov;111(9):733-7.
Chen Shengdi. Diagnosis and treatment of depressive symptoms associated with Parkinson's disease [J]. Chinese Journal of Gerontology, 2018, 37(4): 372-376.
Chen JJ, Marsh L. Depression in Parkinson's disease: identification and management. Pharmacotherapy. 2013 Sep;33(9):972-83.
Liu Li, et al. Improvement of non-motor symptoms of Parkinson's disease by exercise training Effect Study. Chinese Journal of Practical Neurological Diseases. 2017;(24):40-43.
Pohl P, Wressle E, Lundin F, Enthoven P, Dizdar N. Group-based music intervention in Parkinson's disease - findings from a mixed-methods study . Clin Rehabil. 2020 Apr;34(4):533-544.
Huang YH, Chen JH, Loh EW, Chan L, Hong CT. The effect of monoamine oxidase-B inhibitors on the alleviation of depressive symptoms in Parkinson's disease: meta -analysis of randomized controlled trials. Ther Adv Psychopharmacol. 2021 Jan 18;11:2045125320985993.
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