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O type blood couple gave birth to type B blood baby,
husband went crazy on the spot
31-year-old Lin Li (pseudonym) gave birth to a "little beauty" of nearly 7 kg in Hainan Obstetrics and Gynecology Hospital. The strange thing about
is that the couple has blood type O, but their newborn daughter has blood type B!
General male compatriots encounter this kind of problem, they will unconsciously come up with two ideas:
1. Bloody plot, the child was born in the wrong hug.
2. The child is the old man next door, with a green head.
is no exception. After ruling out the possibility that the newborn baby was holding the wrong baby in the delivery room, Bao's father became suspicious: "Did his wife cheat?"
So, despite his wife's confinement, he even had a quarrel just after fighting with death. Helpless, finally agreed to a paternity test.
The staff of the Laboratory of Obstetrics and Gynecology Hospital of Hainan Province sent the blood samples of the two to the blood testing institution for genetic sequencing, and finally determined: mother is a real mother, and father is also a real father! The reason why
gave birth to blood type B babies is because Baoma Linli’s FUT1 gene has heterozygous mutations of 551-552delAG and 881-882delTT. Both of these mutations will cause the H antigen not to be expressed. Linli belongs to . Similar to Bombay blood type ". What is the "Bombay-like blood type" that caused trouble by
?
The Bombay blood type was first discovered by Y.M.Bhende in Mumbai, India in 1952, so it is called the Bombay blood type, which essentially lacks H antigen. In 1961, some scholars discovered a blood type that was similar but not exactly the same as the Bombay blood type, called the "Bombay-like blood type", that is, the sub-Bombay blood type, which is a branch of the Bombay blood type.
"Bombay-like blood type" is a special blood type that is rarer than panda blood. People with this blood type account for only one in 100,000 in the country, and only about 30 cases have been reported in China.
Although Baoma in the news this time showed blood type O, the antigen on the red blood cells contained the B gene. The baby obtained the gene containing blood type B from the mother of the Bombay blood type, and the gene containing blood type O from the father, so it is blood type BO, which is expressed as type B blood.
This phenomenon is very rare. Generally, this blood type cannot be identified in the blood type identification, and the detected blood type shows O type. The genetic law of
ABO blood type
In medicine and genetics, people often use parental blood types to infer children's blood types. Among them, the ABO blood group system is the most familiar blood group system for blood transfusion.
Therefore, Lin Li's lover's doubts are not unreasonable-from the conventional ABO blood type cognition, parents of type O blood really cannot give birth to children of type B blood.
only passes the general blood type test. We would very much doubt the baby's blood type B. But after genetic testing, we found that Ms. Lin Li belongs to the Bombay-like blood type. If genetic testing is not performed, it is easy to suspect that the baby is born. Why does
recommend DNA polymorphism testing?
With the advancement of medicine, more and more cases of ABO blood type genetic abnormality and DNA polymorphism detection confirming the biological blood relationship have been reported. Therefore, it is obviously unwise to exclude the biological blood relationship by violating the genetic law of ABO blood type. DNA polymorphism detection should be used as the criterion.
I hope that every gentleman can give the most basic trust to pregnant mothers. A woman is pregnant in October, and I hope there is someone who understands you.
remind
Under normal circumstances, blood type is the same for life.
If a baby needs blood, such as a baby of AB subtype, and a blood type A transfusion, once a blood transfusion reaction occurs and medical conditions are limited, it may be life-threatening in severe cases.
So for people with rare blood types, such as the Linli genus Bombay blood type, which is more special, what should I do if blood transfusion is needed or blood is needed urgently? Under the current blood shortage problem, even the most basic type B blood is particularly lacking in the area where the author is located, let alone special types of blood.
Therefore, you usually need to consider the situation that you may need to use blood urgently, such as the process of giving birth and surgeryWait, try to enter the local exchange group of rare blood types. When you need to use blood, you can say hello in advance in the group and help each other to live a stable life.
In life, try to minimize accidents, because it is particularly difficult to get blood transfusion. Even pregnant mothers with some blood diseases should find out whether the fetus is abnormal as soon as possible and decide whether to leave or stay.
What other dumbfounding oolongs have you encountered in your work?
Welcome to leave a message to discuss~
References:
1. Pan Yingfang. Xu Qun. Sun Changkui. Song Yonghong. Li Jing. Lv Hongjuan. Zhou Na. Qiao Wenwen. Clinically rare Bombay blood group detection and identification. "Shandong Medicine". DOI:10.3969/j .issn.1002-266X.2020.09.010.
2.Tang Meiyun.Sheng Xiaoqi.Huang Jian.Zhai Zhixiong.Affirmative parent-child case analysis of abnormal inheritance of ABO blood type."Modern Biomedicine Progress".2009, Issue 15, 2866-2868, total 3 .
article source: pediatric medical community channel
author: Albert a dream
editor: Tang Ying
