For medical professionals’ reading and reference only, learn a hot-search drug every day. It is reported that Clostridium difficile-associated diarrhea (CDAD) will occur after the use of almost all antibacterial drugs, including Clindamycin Glucose Injection, and its severity may

Only for medical professionals to read and refer to

Learn a hot-search drug every day

According to reports, Clostridium difficile-associated diarrhea (CDAD) will occur after the use of almost all antibacterial drugs, including clindamycin glucose injection, which is serious. The severity may range from mild diarrhea to fatal colitis because treatment with antimicrobial drugs alters the normal intestinal flora, resulting in the overgrowth of Clostridium difficile.

How should children avoid using clindamycin ?

Clindamycin: Not available for non-bacterial infections!

Because clindamycin glucose injection may cause severe colitis and ultimately fatal, it is only suitable for severe infections with low toxicity that cannot be treated by antibacterial drugs. In addition, clindamycin should not be used in patients with non-bacterial infections, such as most upper respiratory tract infections .

C. difficile produces toxins A and B, which in turn contribute to the development of CDAD; highly toxin-producing strains of C. difficile can lead to increased patient morbidity and mortality, as antimicrobial treatment may not be effective in these infections, possibly Need colectomy treatment.

If CDAD is suspected or confirmed, antibacterial treatment not targeting C. difficile needs to be discontinued; appropriate water and electrolyte management, protein supplementation, and antibacterial treatment targeting C. difficile should be performed according to clinical indications, and surgery should be performed if necessary. treat.

Children’s medication should be paid attention to.

Clindamycin glucose injection can be administered by intravenous drip or intramuscular injection. The recommended dosage for children is as follows:

• Moderate infection: 15-25 mg/kg/day, which can be divided into 3 times (once every 8 hours) or 4 times (once every 6 hours);

• Severe infection: 25-40mg/kg/day, which can be divided into 3 times (once every 8 hours) or 4 times (once every 6 hours) Once every hour), or as directed by your doctor.

In addition, Clindamycin Glucose Injection should not be used by infants under 1 month of age, and by children under 54 years of age. When children use this product, attention should be paid to monitoring liver and kidney function .

Where to learn more popular medicines in Coreli?

Pediatric medicine is no small matter. Some medicines do not have corresponding dosage forms for children. Can children use them? Do I need to adjust the dosage during application?

polyene phosphatidamide contains benzyl alcohol , prohibited for children! The Food and Drug Administration warns infants and young children under 2 years old to be careful with the use of paracetamol and xanthamine... What other drugs are prohibited for children?

The medication information you want is available in the " Pediatrics Medication " column of the doctor's station👇

1. Scan the QR code below

2. Click "Download now "

3. Open the doctor's station App click the column

4. Find " evidence-based medication "

in clinical medicine. Follow the column

Subscribe to the column and read hot-searched medicines every day!

Download Doctor Station App and subscribe anytime and anywhere~