Bacteria from ancient times
It seems that since the birth of human civilization, immortality this topic has never stopped.
For thousands of years, ancient alchemists and modern scientists have hoped to somehow solve this mystery that has troubled mankind for a long time.
Perhaps this is the instinct of biology, and it has a concrete expression due to human thinking.
Becoming a "vampire" seems to be a way to live forever.
To say how crazy scientists are in searching for the secret of eternal life, even the craziest alchemist in ancient times may not be able to compare.
Anatoly Brauchkov, this mad scientist from Belarus , in order to explore this mystery, actually injected 3.5 million-year-old bacteria into his body.
Russian scientist Brauchkov
In Siberia Yakutia , Mamontovaya region there is a permafrost zone . Russian researchers have discovered a species that has never been discovered before. of bacteria.
was later analyzed through experiments and it was found that it belonged to Bacillus and had a history of 3.5 million years ago.
The researchers named it Bacillus F.
Bacteria discovered in Siberia in 2009
But strangely, even after so long, they are still somewhat active.
has a special mechanism that allows them to remain viable in the harshest environments.
Later, in order to verify the influencing ability and activity of this bacterium, scientists conducted relevant experiments in mice.
Experiments on Bacillus F in mice
Results The experiment finally surprised the scientists to find that this Bacillus would affect the vitality of old mice .
and allow it to reproduce again.
Scientists suspect that this bacillus has some ability to keep organisms alive and produce a specific immune system .
In addition, the researchers used MRI to examine mice injected with Bacillus F. The
results show that there are two significantly increased media, which are glutamate and taurine .
These two substances have immunomodulatory and extended cell life expectancy properties.
Taurine is also found in many foods
Judging from the effects of glutamic acid and taurine, the metabolism of mice vaccinated with the vaccine will accelerate .
If calculated according to age, animals injected with the bacteria will be 20%~30% higher.
Not only that, scientists have also conducted similar experiments on fruit flies . Various signs indicate that Bacillus F has a long-term impact on their life span and fertility .
But what makes scientists curious is that despite many experiments, how this changing effect works is still not clear, and the entire operating mechanism is not clear.
And Dr. Victor, an epidemiologist in Yakutsk , believes that to a certain extent, these bacteria are like the elixir .
Re-energized mice
bacteria release bioactive substances throughout their life cycle, thereby activating the immune status of experimental animals.
The result is that mice and fruit flies become more energetic, and old mice can even reproduce again.
Crazy scientist’s longevity bacteria experiment
Dr. Brauchkov of the Russian scientific research group said that now the DNA of Bacillus F has basically deciphered and completely restored the gene sequence. The key to
is how to find which genes can extend the life of bacteria and which proteins can protect the DNA structure from damage.
Bacillus under the microscope F
Such discoveries brought him unlimited imagination, and he believed that this was the hope of future mankind.
In further research, Professor Petrov also led the Siberian team to conduct more extensive research, and more comprehensive bacterial experiments later began.
has related experiments on copepods, mice, crops, and human blood cells.
And researchers are also very optimistic in experiments with bacteria and human blood cells.
Agricultural experiments show that , Bacillus F can stimulate the growth of crops and increase their yields.
The seeds germinated at a temperature of 5 degrees Celsius.
At the same time, in terms of plant disease resistance, , the crops receiving the Bacillus culture solution were not only stimulated to grow, but also had increased frost resistance. The
experimental seeds can germinate at 5°C. This finding is very important for the Siberian environment.
More and more experimental evidence and experimental phenomena show that Bacillus has a certain role in changing , which has also made scientists more and more interested in it.
For Dr. Brauchkov, the capabilities of Bacillus F fascinated him deeply.
Bacillus F
came from 3.5 million years ago. Finally, he made a bold experiment :
In order to feel the "immortality" brought by Bacillus F, he decided to inject himself with inactivated Bacillus .
Even if tests show that bacteria will not cause harm to mice when they enter the body, the human body's structure and its functions are more complex.
It is very dangerous to introduce bacteria that have not been fully studied into human organisms.
But Brauchkov didn't think so. His age was also coming up. Obviously, the potential ability of this bacteria was very tempting.
To understand the mechanisms behind this bacterial vitality how it affects human health .
So when became in 2013, he put his series of ideas into practice.
What will happen if bacteria are injected into the body?
After the crazy experiment
Two years later, passed, and Dr. Brauchkov appeared in front of people again. He was still very excited when discussing Bacillus F.
He said that he had injected bacteria into himself as an experiment before. He had not had a cold or influenza in the past two years, and he felt very healthy physically.
But the whole experiment is not supported in medicine. After all, it is considered a human experiment, even if it is your own body.
is accompanied by controversy and discussion, and this mad scientist is at the forefront.
Perhaps the boldest one is the scientist
. For him, , the body should have undergone some changes, but it is difficult to explain these effects with professional descriptions.
Overall, conducting experiments yourself will require collecting more data and using special medical equipment to detect changes in the body.
Now many years have passed, Dr. Brauchkov has disappeared from public view, and has not discussed related bacterial research with the public for a long time.
In fact, most scientists are confused when studying Bacillus, or it is still unclear how this bacterium can maintain its vitality for a long time.
From the perspective of bacterial classification, Bacillus F, which was discovered in the past, belongs to the family Bacillaceae and is a member of the phylum Gram-positive rod-shaped bacteria.
and 266 types of have been discovered around the world.
Appearance of Bacillus subtilis
In terms of the structure of bacteria, the cell wall of Bacillus is its outermost structure, which is used to protect the bacteria themselves from environmental damage, while maintaining their rod-shaped state and withstanding cell expansion changes.
cell wall is composed of phosphowall and phosphouronic acid . Bacillus subtilis was the first to identify the actin-like cytoskeleton .
and plays a role in cell shape determination and peptidoglycan synthesis of , bacteria with a complete set of peptidoglycan synthase localization.
In short, the role of the cytoskeleton in shape generation and maintenance is important.
Therefore, the discovery of Bacillus subtilis can help scientists further study the formation process and changes of bacteria.
The shining part is the endospore
For them, they restore themselves to oval-shaped endospores.
can remain dormant in this form for many years while being able to withstand extremely harsh environments.
However, endospore is not a true spore form. It is a non-reproductive structure produced by bacteria in the Bacillus phylum.
Endospores allow bacteria to remain dormant for centuries and then reactivate the bacteria when conditions become favorable, bringing them back to life.
research found that endospores are composed of bacterial DNA, ribosomes and a large amount of picolinic dicarboxylic acid.
Endospore formation process
Picolidinedicarboxylic acid specializes bacterial spores and appears to help maintain the dormant capacity of endospores and accounts for 10% of the total spore dry weight.
Bacillus bacteria that form this form can survive without nutrients and are resistant to ultraviolet radiation, dryness, high temperatures, extreme freezing, and even chemical disinfection .
For now, , scientists know the most about Bacillus subtilis, and related research also points to the secret of this bacterium's immortality.
Most of the experimental data of Bacillus come from them.
Due to the current limited level of science and technology, it will be difficult for scientists to unlock the entire secret for a while.
related experimental projects have been launched. The 500-year observation project of and may last longer than any experiment in history.
There may still be many crazy scientists like Brauchkov in the future. Fundamentally, this is the path that humans have always wanted to pursue.