metformin is the first-line first choice and full-process medication for patients with 2 diabetes. Its clinical status is prominent. This is because metformin not only has a diverse mechanism for lowering glucose, good effect on lowering glucose, but also has good safety and a small risk of hypoglycemia. It also has benefits in addition to many lowering effects such as weight loss and cardiovascular protection.
metformin currently has three main dosage forms for sale in clinical practice, namely ordinary tablets, enteric-coated tablets and sustained-release tablets. Different drug dosage forms and different methods of taking them.
ordinary tablets
metformin ordinary tablets are mainly divided into three specifications: 250mg/plate, 500mg/plate and 850mg/plate. Ordinary tablets can take the total dose of a day at one time, or the total dose of a day can be taken in 2-3 times. Taking it in batches can reduce gastrointestinal reactions. Ordinary tablets can be taken before and after meals. Taking with meals can reduce stomach discomfort. Ordinary tablets can be taken in the whole tablet or chewed or broken.
Enteric-coated preparation
Enteric-coated preparations are mainly divided into enteric-coated tablets and enteric-coated capsules. You can take them at a time when taking small doses, and you can take them in 2-3 times. It is basically the same as ordinary tablets. Unlike ordinary tablets, you can take them before and after meals or with meals, enteric-coated preparations need to be taken on an empty stomach at least half an hour before meals. Empty can ensure that the enteric-coated preparations are disintegrated and dissolved in the intestines, and avoid the tablets that are taken with food and stay in the stomach for too long and release in advance.
sustained-release dosage form
metformin has a sustained-release tablet and a sustained-release capsule. The sustained-release preparation has a long time to maintain the sugar-lowering effect and can usually be taken once a day. It is recommended to take it at dinner, both before and after meals. If you use a large dose, such as 2,000 mg a day, you can also take it in two doses. The most prominent advantage of the sustained-release dosage form is that compared with the other two preparations, the gastrointestinal adverse reactions of the sustained-release dosage form are mild
How much metformin takes every day to lower the sugar effect?
metformin lowers blood sugar. The recommended minimum dose is 500mg/day and the maximum dose is 2550mg/day. Between 500mg-2000mg, the dose of metformin is proportional to the efficacy. The larger the dose, the better the effect of lowering the glycemic. On the premise that the patient can tolerate it, the target dose of metformin should reach 2000mg/day. Generally speaking, if metformin increases the dose, its gastrointestinal adverse reactions do not increase accordingly. Avoid the gastrointestinal adverse reactions of metformin. It is also recommended to start from a small dose and gradually increase the dosage to the target dose.
