Qianjiang Evening News·Hour News Correspondent Wang Wenting Reporter He Lina
45-year-old Ms. Chen (pseudonym) is an absolute "slim stocking control". Except for the cold winter months, she often likes to travel in stockings, revealing her slender legs, which is quite eye-catching. But in the past few months, she has put away her stockings abnormally, put on her jeans silently, and wrapped them tightly.
It turned out that Ms. Chen accidentally found a small wound on her right calf. At first she didn't care, but she didn't expect that the wound would get bigger and bigger, until her entire calf was red and swollen, which was thicker than her left leg. Ms. Chen, who thought it was wrong, went to the pharmacy to buy medicine on her own, but the effect was very little.
A few days later, Ms. Chen was wet with another rain, and she had a fever. The local hospital provided anti-infection treatment for her. The symptoms of high fever lasted for more than half a month but still did not subside. In addition, the family also found that Ms. Chen began to have symptoms of drowsiness and could not wake up no matter how she shouted. "I always felt unbearable headaches, but later it became so difficult to communicate with people normally." After inquiring from many sources, Ms. Chen came to Hangzhou First People's Hospital for treatment.

Image source: Visual China
The doctor recalled that when he was admitted to the hospital, Ms. Chen's body temperature was as high as 40.7 degrees, and various inflammatory indicators were significantly increased. There were skin infection and scabs on the right lower limb and back. After asking about the medical history, I learned that Ms. Chen had systemic lupus erythematosus and needed to take medicine for a long time. At this time, the doctor had made a preliminary judgment. After giving empirical medication, doctors at the same time conducted pus culture of the wound, blood culture, cerebrospinal fluid culture and NGS (second-generation high-throughput sequencing technology) on Ms. Chen at the same time. After careful cultivation and observation, the rare surviving nukaci was finally found in the specimen. Through precise treatment of pathogenic bacteria, Ms. Chen was successfully discharged from the hospital a week later.
Cen Ke, the Laboratory Department of the First Hospital of the City, introduced that nukazin is a gram-positive aerobic bacteria , which is affiliated to the genus Actinomycetes, which is rare in China.

Noccacia is widely distributed in the natural environment, such as soil, water, rotten plants and animals, etc. It can invade through respiratory tract and skin wounds, and can easily spread through blood to the whole body, thus causing infectious diseases of multiple organs and can also cause rare brain abscess .
Noccacia does not belong to the normal bacterial flora of in human , but is a conditional pathogenic bacteria that mainly causes exogenous infections and is more common in patients with immune deficiencies. Relevant medical research data show that among the infections caused by nukacia, 64% of patients have impaired immune function.

Dr. Cen Ke analyzed that the reason why Ms. Chen was infected with this disease may be related to her low immune function. "Suffering from lupus erythematosus requires medication to control the condition, and is in an immunosuppressive state for a long time. She is a susceptible group of people who are disseminated in the cranium through trauma, causing infection, and then related neurological symptoms appear. However, for people with normal immune function, the probability of infection of Nokarcia is not very high, so there is no need to panic too much.
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