Wuhan University Hospital Management Institute undertakes the UNICEF commissioned project:
curbing children's antimicrobial resistance project
microbial resistance is a major challenge in the global public health field. The Chinese government attaches great importance to strengthening the management of antimicrobial drugs to curb microbial resistance. Under the working mechanism of joint prevention and control of bacterial resistance, all relevant departments have thoroughly implemented the relevant requirements of the "National Action Plan for Containing Antimicrobial Resistance (2016-2020)". A series of actions have been taken, and important progress has been made in antimicrobial drug development, production, distribution, use, environmental protection, publicity and education, and international cooperation. The basic mechanism for antimicrobial drug management has been established.
In recent years, with the rapid increase in neonatal wards and neonatal intensive care units in my country, the prevention and control of infections in neonatal medical care institutions and wards, especially multidrug-resistant bacterial infections, has become an urgent problem to be solved. In particular, the detection rate of third-generation cephalosporin-resistant Escherichia coli, Klebsiella pneumoniae, and carbapenem-resistant Klebsiella pneumonia is gradually increasing. According to the latest data from the National Nosocomial Infection Surveillance Network, the prevalence rate of neonatal hospital infection in 2018 was 3.5%, which was higher than the overall level of inpatients (2.0%); in 2019, the hand hygiene compliance rate of medical staff in 1479 hospitals was less than 80%. The correct rate is 82.8%. Hand hygiene is one of the basic measures for infection prevention and control, but the implementation is not ideal. The accessibility and rational use of antibacterial drugs in neonatal patients also need to be further improved. The types of antibacterial drugs available to neonatal patients are limited, and the use of broad-spectrum antibacterial drugs is increasing.
Antimicrobial resistance is a natural phenomenon, affected by a variety of biological and environmental factors. No single measure alone can solve the problem of antimicrobial resistance. Both the World Health Organization's Global Action Plan and China's National Action Plan emphasize social participation and the concept of "One Health". Regarding the control of drug resistance, the key measures implemented in the health care system are mainly launched from two aspects: prevention, control and treatment: First, the prevention and control of infections in communities and health care institutions, which reduce the incidence of infections and thereby reduce antimicrobial drugs The demand for treatment is to curb microbial resistance; in addition, because the abuse and overuse of antimicrobial drugs will exacerbate antimicrobial resistance, another important measure is to optimize the use of antimicrobial drugs.
The National Health Commission has issued a number of work notices and technical specifications for infection prevention and control in medical institutions and the rational use of antibacterial drugs, and promoted the implementation of relevant requirements by medical institutions through inspection, monitoring and feedback. For example, the National Health Commission issued "Infection Prevention and Control Measures in Critical Neonatal Care Centers" and "Basic System of Infection Prevention and Control in Medical Institutions" as national guidelines for infection prevention and control in 2018 and 2019 respectively. Guidelines for Clinical Application (2015 Edition)" and "National Guidelines for Antimicrobial Therapy" serve as national guidelines for clinical application of antimicrobial drugs.
Currently, there is limited research on the implementation of the above guidelines and the obstacles and problems encountered. This topic aims to understand the level of awareness, implementation status and problems of standard measures for infection prevention and control and clinical application guidelines for antimicrobial drugs in the process of neonatal medical practice in my country, and clarify the obstacles to their implementation, in order to explore how to establish appropriate medical practices for neonates Feasible infection control measures and antibacterial drug use specifications provide reference information. It is hoped that through this study, relevant departments and medical institutions can better optimize the implementation of infection control measures and provide decision-making reference for the use of antibacterial drugs, thereby reducing the occurrence of neonatal drug-resistant infections and irrational use of antibacterial drugs.
2020 Antimicrobial Awareness Week
Microbial resistance has become a major challenge in the global public health field. The Chinese government attaches great importance to strengthening antimicrobial drug management to curb microbial resistance. The "Report" is mainly divided into 4 parts, namely the status quo and effectiveness, relevant progress of the National Action Plan, safeguard measures, problems, strategies, etc., which comprehensively and objectively demonstrate the current status and thinking of antimicrobial drug management and drug resistance in China.
