According to "Quick Technology" report on October 12, 2022, on October 12, the well-known singer Li Yuchun revealed that she was suddenly told by a doctor last year that she had ankylosing spondylitis. She also said that this disease often recurs. Once, when she was having a concert, the disease recurred due to excessive rehearsals, and it was very serious. She finally had to get into a wheelchair. In fact, many people in the entertainment industry suffer from similar diseases. Public reports include well-known singers and actors such as Jay Chou , Ada Choi , and Zhang Jiayi .
For this kind of mandatory spondylitis, I interviewed Director Li for this purpose. He reminded office workers that mandatory spondylitis should be prevented in this way.
Microresonance images of ankylosing spondylitis
1. Understand the knowledge of ankylosing spondylitis
Understand the knowledge of ankylosing spondylitis. It is a common clinical disease and is relatively difficult to treat. It is extremely harmful to people. The prognosis is not ideal. Most of them can only be controlled and cannot be completely cured. Some may even cause limb disability and even life-threatening.
Ankylosing spondylitis is mainly a disease of rheumatism and immunity, and it also intersects with orthopedics. It is mainly symptom of inflammation of the sacroiliac joint and spinal attachment point. It has a strong association with HLA-B27. Certain microorganisms (such as Klebroliformis) share common antigens with the susceptible tissues, which can trigger abnormal immune responses. It is a chronic inflammatory disease characterized by the large joints of the limbs, the annulus of the intervertebral disc and its nearby connective tissues, as well as the antonymosis of the joints of and .
At present, the research on this disease is gradually deepening, and the specific cause of the disease is not very clear and needs further research. Its characteristic is that it is a chronic disease with the spine as the main lesion site, which involves the sacroiliac joint, causing spinal ankylosing and fibrosis , causing eye, lung, muscle and bone lesions to varying degrees. It is an autoimmune disease .
Understanding the occurrence of ankylosing spondylitis has a positive effect on our prevention and treatment of ankylosing spondylitis. We should understand all the relevant knowledge about ankylosing spondylitis and provide support for preventing mandatory spondylitis.
2. Beware of trauma-induced ankylosing spondylitis
Strictly speaking, trauma will not cause ankylosing spondylitis, but among the existing ankylosing spondylitis patients, ankylosing spondylitis induced by accidental injuries account for a large proportion, such as car accident injuries, construction injuries, trauma caused by physical exercise, accidental falls, and trauma caused by fighting, etc., the original ankylosing spondylitis can be further aggravated or the already stable ankylosing spondylitis recurs. Therefore, beware of trauma-induced ankylosing spondylitis.
Train in car accident
3. Prevent ankylosing spondylitis caused by infection
In ankylosing spondylitis, it is closely related to bacterial infection. Some patients are induced by bacterial infection, such as the common Klebacterium, and related reports show that it is related to intestinal infection. The stool bacteria cultured in patients with ankylosing spondylitis showed that the positive rate of Klebsiella pneumoniae was 79%, while that was 30% in normal populations, indicating that the frequency of Klebsiella pneumoniae infection was significantly higher than that of normal people.
The role of the intestinal tract in the onset of sero-negative spinal arthritis (SPAS) has been highly valued in recent years. The abnormal local immune defense mechanism of the intestinal tract and the increase in the incidence of asymptomatic intestinal inflammation provide a basis for clarifying the pathogenesis of SPAS. We conducted fibroccoloscopy and biopsy on 20 patients with ankylosing spondylitis (AS), and cultured Klebsiella stool pneumoniae in 70 patients with AS to explore the relationship between intestinal inflammation, bacterial infection and the occurrence and development of spinal arthritis [1].
It can be seen that avoiding Klebsiella intestinal infection in daily life, work and study has an important role in preventing ankylosing spondylitis.
Klebsiella that causes ankylosing spondylitis
4. Pay attention to ankylosing spondylitis caused by decreased immunity
In the causes of ankylosing spondylitis, it is mainly closely related to the decrease in immunity. The decrease in immunity and the decrease in the body's resistance, resulting in abnormal immune response in the human body, invading the sacroiliac joint, spinal bone process, paraspinal soft tissue and peripheral joints, thereby inducing ankylosing spondylitis. Therefore, improving the body's immunity and strengthening exercise can reduce the occurrence of ankylosing spondylitis.
5. Pay attention to prevent ankylosing spondylitis caused by genetic factors
In the population of ankylosing spondylitis, genetic factors are an important cause of ankylosing spondylitis. Generally, most ankylosing has a family genetic tendency. If ankylosing spondylitis is contained in the previous generation of ankylosing spondylitis, the incidence rate of the next generation is increasing. Therefore, it should be noted that once there are genetic factors in the family, in the next generation, you should pay attention to strengthening prevention, avoid the inducing factors of ankylosing spondylitis, conduct relevant examinations regularly, and pay attention to prevention.
Ankylosing spondylitis (AS) is a complex disease involving multiple risk factors, mainly genetic and environmental factors. Among them, human leukocyte antigen (HLA)-B27 is the main susceptible gene for AS. Non-major histocompatible complexes are susceptible to genolos, such as endoplasmic reticulum aminopeptidase (ERAP) 1 and interleukin 23 receptor (IL-23R), which may be involved in the development of arthritis [2].
5. Develop a good lifestyle and habits
In ankylosing spondylitis, some patients induce ankylosing spondylitis due to a bad lifestyle, which may cause ankylosing spondylitis. Therefore, you should pay attention to developing a good lifestyle, such as not sitting down for a long time without moving, doing 50 minutes of action, and standing up and moving for 10-15 minutes. Avoid placing pillows when sleeping and not sleeping in a soft bed. It is best to lie flat and keep your back upright when sleeping. Don’t watch mobile phones and play games for a long time. When cold weather comes, pay attention to keeping warm, etc., to develop a good lifestyle, which can prevent or reduce the occurrence of ankylosing spondylitis.
Ankylosing spondylitis is an extremely harmful immunologic disease. In severe cases, it can cause disability and even life-threatening. As office workers, you can take corresponding measures to prevent, prevent or reduce the occurrence and development of ankylosing spondylitis, and reduce the harm caused by ankylosing spondylitis.
Reference
1. Liu Yi, Cai Xinghua, The role of intestinal inflammation and bacterial infection in the onset of ankylosing spondylitis, Chinese Journal of Internal Medicine, 1995 (5)
2. Yu Wenwen, Zhao Dongbao, Research progress of genetic factors in the pathogenesis of ankylosing spondylitis, "Medical Review", 2016 (20)
