A relationship between migraine and stroke has been proposed for many years, but no conclusive evidence has yet been reported. Several theories regarding hypercoagulability have been discussed in relation to ischemic stroke and migraine, especially migraine and aura. To study the relationship between hypercoagulability and migraine, Haidy EI-Shebawy et al. evaluated migraine by assessing protein C, protein S, and antithrombin III serum levels and correlating them with brain MRI findings, if present. Hypercoagulable state in individuals with headache. The research results were announced in the form of an electronic poster at the 2022 European Congress of Neurology (EAN 2022).
Author of this article: Yimaitong EAN reporting team
Yimaitong compiled and compiled, please do not reprint without authorization.
Study Introduction
This case-control study included 70 subjects (35 migraine patients and 35 healthy people). Subjects underwent the following examination:
A-Clinical Assessment: Comprehensive medical history, physical examination, and neurological examination. Migraine intensity was assessed using the Numeric Rating Scale (NRS) for pain.
B - Radiological evaluation: Brain magnetic resonance imaging (MRI) (T1, T2 and FLAIR) was performed at the Department of Diagnostic Radiology, Cairo University Hospital.
C - Laboratory tests: Measure protein C, protein S and antithrombin Ill levels.
Key Study Results:
1. Mean serum levels of the protein S and antithrombin III were significantly lower in migraineurs compared with controls.
2. Compared with controls, brain MRI of migraine patients shows white matter hyperintensity and ischemic lesions.
3. There is a significant negative correlation between serum protein C level and migraine intensity. Serum protein C deficiency is considered an independent predictor of migraine intensity.
Conclusion
There is an association between migraine and hypercoagulability, which may indicate an increased risk of cerebral ischemia in migraineurs.
Yimaitong Compiled from: The Relation between blood hypercoagulability and migraine. EAN 2022.
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