warfarin can prevent and treat deep vein thrombosis and pulmonary embolism. It can also prevent myocardial infarction post-thromboembolic complications, prevent atrial fibrillation, heart valve disease or artificial heart valve disease_span2 Thromboembolism caused by valve replacement surgery is commonly used. It is also necessary to be very careful in the application process of patients. If the dosage is too large, there will be a risk of bleeding, while the dosage is too small to achieve the purpose of treating thrombosis, which will cause embolism . Therefore, when using warfarin, doctors often require patients to measure the INR value regularly, and adjust the dosage of warfarin in time according to the INR value.
For warfarin, not only the dosage affects the treatment effect, but drugs and food will also have a certain effect on the treatment effect of warfarin. Here is a brief summary for everyone What drugs and foods will affect the effect of warfarin treatment?
Many drugs may enhance the anticoagulant effect of warfarin as common ones: aspirin, phenylbutazone, azithromycin, cephalexin, cefuroxime, levofloxacin_ oxofloxacin Star, moxifloxacin, tetracycline, clarithromycin, erythromycin, fluconazole, ketoconazole, itraconazole, omeprazole, simvastatin; drugs that reduce the anticoagulant effect of warfarin : Phenobarbital, carbamazepine, rifampicin, isoniazid, sodium valproate, spironolactone, vitamin C, etc.
Herbs may also increase the anticoagulant effect of warfarin: ginkgo, garlic, angelica, papaya, danxin.
Herbal medicine reduces the anticoagulant effect of warfarin: ginseng, Hypericum perforatum.
Foods can also affect the therapeutic effect of warfarin. Foods that affect the therapeutic effect of warfarin are mainly vitamin K-rich foods such as pork liver, green tea, red leaves of common vegetables, broccoli , sprouts, cabbage, rapeseed oil, cucumber skin (not peeled cucumber), parsley, beans, pistachios, spinach leaves, soybeans, soybean oil, water cress, etc. Note that the diet should be relatively stable during the period of taking warfarin. Don't suddenly eat a large amount of green leafy vegetables and leaves containing vitamin K a day. The diet should be reasonable. Secondly, remember not to drink alcohol while taking warfarin.
At the same time, you should always pay attention to whether there is bleeding tendency while taking warfarin, such as bleeding gums, subcutaneous occult blood, red spots on the body, fecal occult blood , etc., should be paid attention to. , See a doctor in the hospital in time, take the medicine strictly according to the doctor's advice, do not increase or decrease the dose or stop the medicine without authorization, and monitor the INR value regularly according to the doctor's advice.
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