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On June 23, 2022, Ansuman T. Satpathy's team from Stanford University published an article titled Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence in Cancer Cell.
Genome-wide CRISPR screen reveals chromosomal remodeling critical for maintenance of exhausted T cells
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Dahe Daily·Yu Video Reporter Liu Ruichao Kang Yafei There is a famous story in "Liezi·Tang Wen", which is "Two Children Debating the Sun" in the textbook, "Confucius traveled eastward and saw two children arguing and asked why." Two children analyze from different angles when the
The "smallest sun of the year" appeared on Monday, and the "dog days" are gradually approaching
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Satellite images from NASA and the European Space Agency have captured the appearance of the first sunspot of the new solar cycle. Sunspots are areas of intense magnetic activity, dark spots visible on the surface of the sun. Sunspot activity rises and falls with an approximately
"Space Observation" The beginning of a new solar activity cycle
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Humans can be said to be the most advanced animals on the earth. There is almost nothing that humans dare not eat. In times of famine, people who are too hungry will eat tree bark, leather belts, grass roots, soil, etc. Nowadays, people's living conditions are better and they eat
There is a plant that is full of treasures, but is often "peeled". Have you ever seen it?
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In cartoons, the "omnipotent" Doraemon often takes out various magical props from the future world from his four-dimensional pocket in order to help Nobita. They are full of creativity and science fiction imagination, just like Doraemon's pocket. It's an inexhaustible treasure ch
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On July 1, the official website of the New Cornerstone Researcher Program released the latest application guidelines. The "New Cornerstone Researcher Project" is a new basic research funding project led by scientists and funded by Tencent. It is a public welfare and independently
The big project is coming! 60 people will receive five-year funding, RMB 3-5 million per year
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According to reports, experts from the Japan Marine Research and Development Agency discovered an extremely rare giant fish in the deep sea. Its body is more than 2.5 meters long, its skin is dark blue-purple, and its mouth is split, making it look very strange. It is large, with
2,000 meters under the sea, a brand new species was discovered in Japan. It is huge. Has it mutated?
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A few days ago, the famous American documentary producer Jeremy Corbell mentioned an incredible thing: Dozens of US sailors confirmed that during a training exercise in 2019, the warship was surrounded by a UFO group. In terms of number, at least There are more than 100 UFOs, and
Performance exceeds human technology! Dozens of U.S. sailors confirmed that they were surrounded by hundreds of UFOs during training
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But dinosaurs luckily escaped this disaster and dominated the Jurassic and Cretaceous worlds. So, what was the cause of the mass extinction of terrestrial life at the end of the Triassic?
How to become a land overlord for 130 million years? Dinosaur: Put on a "down jacket"
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The rarest and most bizarre aquatic creatures in the world, many people have seen them for the first time. Which ones have you seen? Type 4: Dumbo Octopus, don’t you think it’s cute when you hear this name? It was discovered by marine biologists at 1,600 meters on the bottom of t
Continuing with what we mentioned in the last issue, weird and weird creatures, let’s take a look at the different ones today.
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Batteries for electric cars make lithium a coveted raw material The lack of raw materials has put pressure on supply chains. A latest survey concluded that Germany is currently experiencing the most severe shortages of nine minerals, seven of which mainly come from China. 9 raw m
Latest research: 7 of the 9 raw materials that Germany is seriously lacking mainly come from China
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Plants are another perspective for us humans to understand and explore the world. In their own world, their growth, blooming, fruiting, withering and prosperity, and their life processes are all very clearly visible. However, some of the characteristics they have developed in ord
In order to survive, plants have evolved these 6 unique abilities. Netizens: Plants are also "crazy"
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For ocean areas, there are countless large and small islands. However, since islands are concentrated in the ocean, resources are indispensable if you want to survive on an island. Among them, there is a very unique island located in the South China Sea of my country, which is
More precious than oil! Satellite view of Yongshu Island: surrounded by sea water, how can there be fresh water?
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Air turbine expander. Can you imagine that the air that is everywhere around us can both store energy and generate electricity? In Changzhou, Jiangsu, there is such a power station that uses air to store energy and generate electricity - the Jintan Salt Cave Compressed Air Energy
The world's first "non-supplementary combustion" compressed air energy storage power station is put into operation and the "air power bank" hidden underground
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For the first time in the world, high-quality whole-genome data of E. ovodovi, an extinct Equus, was successfully obtained, and the evolutionary history of Equus was reconstructed. It was found that Ovodovi belongs to three subgenus of Equus, excluding horses, zebras and donkeys.
Ancient DNA research by a team from Jilin University and Northwest A&F University provides important evidence for the evolutionary history of Equus
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Earth farthest from the sun: orange sunset over water, with a ship in the foreground. On July 4, 2022, Earth will reach aphelion—our farthest point from the sun—at 7:00 UTC. But the Northern Hemisphere is experiencing its hottest summer, so you understand that our distance from t
Today, the Earth is farthest from the Sun
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Hi guys! I am the kitten of "Kitten Loves the Kitchen", and I meet you again today to share life, food, and happiness! Today, Mao Mao brings you a cold dish made from lotus root. The lotus root slices made in this way have a crisp texture, spicy and sweet taste, and are particula
Mixing lotus root with soy sauce like this will give you a crispy texture, sweet and sour taste, and is especially enjoyable in summer.
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"Those Years in the Grand Temple of Childhood" (Serial No. 115)
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Written by: Ning'er [Original content, personal collection and forwarding are welcome] Many people born in the 80s and 90s are only children, and now there are also many young people who only have one child. The pressure of raising a child is less for an only-child family, but it
Parents who think like "Let your son look for an only child will save you ten years of struggle in the future" are slapped in the face.
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The most effective changes come from feeling good. This is the 31st article of intensive reading and sharing in the book "Fogg Behavior Model". Why are people unwilling to change themselves? Because change is painful, people seek advantages and avoid disadvantages, and of course
Does change have to be painful? Dr. Stanford says the most effective changes come from feeling good
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On her wedding day, a 30-year-old bride was regretted by her husband. Her family came to ask for an explanation. The groom said, "The bride had a private meeting with her ex-boyfriend on the eve of her wedding." Faced with the groom's remarks, the bride's father said, "My daughte
The bride met her ex-boyfriend on the eve of her wedding. The groom wanted to regret the marriage after seeing it, but the bride’s parents did not agree.
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The S28 season has been going on for some time, and the winning rates of each position have basically stabilized, and the overall game situation will not make too big a difference. Generally speaking, the pattern of this season has changed a bit. Many heroes that were very strong
In the S28 season, the five positions are divided into codes. The middle and jungle have risen due to the rise of stupid shots. The shooters will choose him.
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