On June 24, according to Taiwan’s Zhongshi News Network, Taiwan’s Department of Disease Control and Prevention announced the first confirmed case of imported monkeypox in Taiwan. The patient was a man in his 20s.

Introduction: The first confirmed case of monkeypox appeared in Taiwan; the first case of monkeypox in children was discovered in France; the United States canceled abortion rights; Pfizer/BioNTech announced the preliminary results of the trial of Omicron vaccine and bivalent vaccine...BioExploration Follow the "medicine" news with you and explore the value of biotechnology!

01 Taiwan’s first confirmed case of monkeypox

html On June 24, according to Taiwan’s Zhongshi News Network, Taiwan’s Department of Disease Control and Prevention announced the first confirmed case of monkeypox imported from abroad. The patient was a man in his 20s. The man developed symptoms such as fever, sore throat, muscle aches, rash, and swollen lymph nodes in his groins on the 20th. He sought medical treatment on the 21st and 22nd, and was confirmed to be infected with the monkeypox virus on the 24th. Monkeypox is a self-limiting disease that can be cured by the body in most cases, but it can also be fatal. Monkeypox virus is roughly divided into the West African clade and the Congo Basin clade. The case fatality rate of the West African clade is about 3%, while the case fatality rate of the Congo Basin clade is about 10%.

02 The first case of monkeypox in a child was discovered in France

On June 26, local time, according to French media reports, on the evening of the 25th, the Île-de-France regional health agency announced that a child was infected with the monkeypox virus. This is the first case of monkeypox in a child discovered in France. pox cases. The patient is a primary school student and his condition is currently under control with no risk of worsening. According to relevant statistics, more than 300 cases of monkeypox have been confirmed in France so far.

03 The United States cancels the right to abortion

On June 24, local time, The U.S. Supreme Court ruled to cancel the constitutional right to abortion and overturned the "Roe v. Wade" case. The 1973 ruling in this case legalized abortion in the United States. The ruling means that U.S. states can enact their own laws on abortion, upending a landmark precedent from nearly 50 years ago and challenging reproductive autonomy in modern America.

04 Pfizer/BioNTech announced the trial results of Omicron

vaccine and bivalent vaccine

On June 25, Pfizer/BioNTech announced the preliminary results of the trial of Omicron vaccine and bivalent vaccine. Similar to Moderna's results, targeting Omicron as a second booster shot produced more -neutralizing antibodies . Pfizer/BioNTech has made both the single price of Omicron and the original version of Omicron plus the second price, and also made the existing dose of 30 micrograms and the increased dose of 60 micrograms respectively. Judging from the test results, Omicron produces more neutralizing antibodies against Omicron at a single price, and increasing the dose also corresponds to more neutralizing antibodies.

05 Gilead Hepcludex Phase 3 clinical success

On June 23, Gilead announced the latest data from the Phase 3 MYR301 trial. The results showed that its first viral entry inhibitor, Hepcludex (bulevirtide), was highly effective and significantly reduced the viral load after 48 weeks of treatment. At the same time, Hepcludex treatment had a positive impact on patient-reported outcomes (PROs), with significant improvements in "nearly all health-related quality of life domains assessed" on the Hepatitis Quality of Life Questionnaire. Additionally, a significantly higher proportion of patients who received Hepcludex at the 2 mg and 10 mg doses achieved a combined virologic and biochemical response compared with patients who did not receive antiviral therapy during the study period (2%), 45% and 10%, respectively. 48%.

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