After the beginning of autumn, ordinary people began to enjoy these days of cool autumn, but it was a painful beginning for patients with allergic asthma. According to clinical medical statistics, 80% of allergic asthma patients develop diseases or have repeated asthma in late autumn. On August 25, a family member consulted Gileadkang: The child was fifteen years old, but asthma had been on repeated attacks for three years, and it always had an attack every autumn. What should I do? Clinically, the number of children who are "complained with each other" with this patient is increasing year by year. How to treat allergic asthma?
Asthma
Asthma is a relatively stubborn disease. If treatment is ignored, it can accompany you for life. Most asthma patients have allergic symptoms or have allergic rhinitis . Asthma patients with allergic rhinitis will have symptoms such as sneezing, runny nose, itchy nose, itchy eyes, and tears. Allergic asthma is likely to occur in children with allergic constitutions. Allergic constitution refers to the innate defects in the body's immune function. After foreign-related antigenic substances (pollen, mites, fungi, etc.) enter such a human body, they will combine with specific antibodies in the body to produce a series of harmful reactions. Repeated attacks of allergic asthma in autumn are difficult to cure, especially for children and the elderly, they have poor physical fitness and are more likely to cause other lesions.
This disease is partially related to genetics. One of the parents has asthma, and the child has asthma chance of 50%. Both parents have asthma, which can be as high as 70%. On the other hand, most children have acquired allergic constitution. The better the living conditions of a family, the higher the proportion of allergic diseases in children. Electromagnetic radiation from various household appliances, computers and mobile phones is a major factor in causing allergic constitution. Because children aged 3 to 6 years old are lively and active, and like curious new things, when they often sing with a microphone, watch TV at close range or get close to the computer, electromagnetic waves are very easy to enter their bodies. Children's own resistance is lower than that of adults, and their body's ability to regulate after radiation is relatively poor. Therefore, parents should usually reduce the time for their children to get close to radiation as much as possible.
Treatment of allergic asthma
In the treatment of asthma, I only use some drugs simply. Many friends in life have not undergone regular treatment. But a considerable number of patients are not aware of or unwilling to receive such temporary treatment until asthma recurs. In addition, many patients also mistakenly believe that they only take medication when there are symptoms, spray more when there are symptoms, and reduce or stop taking the medication when there are symptoms. Many people do not take medication on time because they are afraid of troubles in operation; do not insist on using the side effects of hormones; and even are unwilling to persist in long-term use of medications, which are all reasons that affect the efficacy of inhalation treatment.
What should I do if I still cannot control my asthma after treatment?
Currently, the treatment (management) of asthma depends on inhaled glucocorticoid treatment, but some patients are intolerant of inhaled corticoids alone or long-acting bronchodilators combined with leukotriene inhibitors. There has been a huge development in the field of biotherapeutics over the past two decades, with three molecules currently available, and there are two different and highly selective methods to interfere with allergic and eosinophilic airway inflammation in most asthma.
Goal for asthma patients —the world's first asthma targeted therapy drug Omalizumab (Zhuo), officially obtained approval from the China Food and Drug Administration (CFDA) to treat adults and adolescents (12 years old and above). After ICS/LABA treatment, moderate to severe persistent allergic asthma still cannot effectively control symptoms.
new drug for asthma—Omalizumab
Omalizumab is the first FDA-approved biological agent for the treatment of severe asthma. It is a humanized anti-IgE antibody that specifically binds to the Fc portion of free IgE and the omamab:IgE complex. This can reduce free IgE levels and prevent IgE from binding to FCεRI. When IgE does not bind to FCεRI, there is no mast cell degranulation and the release of inflammatory mediators is inhibited. IgE is also responsible for regulating its own receptors, and by reducing free IgE levels, omalizumab can also reduce FCεRI expression.
Omalizumab (Omalizumab ) is mainly used in patients with moderate and severe asthma with allergic characteristics after the combined treatment of ICS and LABA. It can relieve asthma symptoms, reduce the application of relief drugs, and reduce the worsening of asthma. omalizumab is usually well tolerated, and the incidence of overall adverse events of omalizumab is similar to that of the control group. No obvious toxic side effects of anti-IgE treatment have been found, but because the drug has been used in clinical practice for a short time, its long-term efficacy and safety need to be further observed.
Allergens that cause allergic asthma:
Inhalation allergens: The most important allergens that cause this disease are dust mites inhaled from the respiratory tract. About 80% of asthma attacks are associated with this mites attached to the dust. They often fly in the air, float for a long time, and are constantly sucked in by children. This kind of mite is hard to see with the naked eye. Only under a microscope can it see its "true face" clearly, so it increases the difficulty of prevention.
Intake of allergen : Enter the mouth with food. Foods that are prone to cause include milk, eggs, fish and shrimp, potatoes, bamboo shoots, strawberries, pineapples, foods containing spices, wheat foods, etc. Most of them belong to the opposite sex protein category.
Contact allergens: includes cosmetics, sulfonamide ointment, camphor, sprinkle, iodine wine, red mercury, rubber glue, plastic toys, etc.
Infectious allergens: common ones include pneumoniae , Haemophilus influenzae , pneumoniae Creole , Staphylococcus aureus, hemolytic streptococci , adenovirus , respiratory fusion virus, parainfluenza, etc. They are the main "culprits" that cause asthma attacks in children under 5 years old.
In addition, children with allergic constitutions are often allergic to "cold". This is one of the reasons for repeated attacks of allergic asthma in autumn and winter. Once they encounter cold air and cold wind, they will cause allergic attacks. Parents often lack understanding of this type of inducing factors. It has been proved that cold air is an important cause of asthma attacks. Every autumn, when cold air travels south, the number of children with asthma attacks has increased significantly. Pay more attention to the weather in the autumn season. When the cold air arrives, keep warm to prevent colds. In short, you should add or reduce clothes according to the temperature and body comfort.
Prevent asthma, it is urgent to
1 First of all, you should develop the good habit of not picky about food and eating a balanced diet in normal times. In addition, the climate in autumn is dry, and children often have dry and hot symptoms such as dry mouth, dry skin and dry stool. Traditional Chinese medicine believes that the lungs like moisturize and hate dryness, so you should eat more moisturize and moisturize foods, such as raw pears, water chestnuts, pomelo, sugarcane, etc., which have a preventive effect on allergic asthma. In addition, be careful not to eat too much high-protein foods such as hairy crabs.
2 Secondly, exercise more, strengthening children's physical exercise, and enhancing their physical fitness are powerful measures to prepare for allergic asthma attacks for a long time, especially for children with weak and allergic constitutions.
3 Finally, improving the living environment is also important for preventing allergic asthma. Studies have shown that the positive rate of mite IgE in children is mainly related to the floor and bedding of the living room, especially in the residential buildings with good sealing properties. The positive rate of mite IgE in children has increased significantly, so parents should try to keep indoor ventilation as much as possible. It is best not to use wool fabrics for bedding, try to get enough sun. It is best to use boiling water to blanch the underwear of a sick child after washing it to reduce the presence of mites.
Gileadkang warmly reminds: Allic asthma can cause serious complications, such as: sudden death, because it often has no obvious precursor symptoms, and once it occurs suddenly, it often dies without time to rescue; there are also lower respiratory tract and lung infections, water electrolytes and acid-base imbalance, pneumothorax and mediastinal emphysema , respiratory arrest and respiratory failure, multi-organ insufficiency and multi-organ failure, etc. I hope everyone has a correct understanding of the harm caused by asthma. At the same time, it is necessary to detect and treat asthma early, so that it can be helpful for the treatment and control of asthma.
comprehensive drug (omalizumab) is considered in various factors such as the quality, safety, price and distance. It is recommended that patients leave messages or send private messages to consult Gileadon experts. Do not search for some unreliable drug information or folk remedies online to avoid delaying the condition. In addition, we have collected and sorted out the questions asked by patients/ and published the relevant solutions on Gilead Kang. Patients and their families are welcome to pay attention to/ to read.
