The investigation and handling results of medical research integrity cases in some institutions. The paper "Caprin1 targeted by circularcirc_0000885 in the tumor progression of osteosarcoma" was published by Feng Qing, the corresponding author of Cangzhou People's Hospital of Heb

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The investigation and handling results of medical research integrity cases in some institutions. The paper

China Cosmetic and Medical News Center

This article is reproduced from National Health Commission Science and Technology Education Department

Some institutions' medical research integrity case investigation and handling results (November 12, 2021)

The investigation and handling results of medical research integrity cases in some institutions. The paper

Now the investigation and handling results of medical research integrity cases recently reported by some medical institutions affiliated to health administrative departments are reproduced as follows:

1, Tianjin People's Hospital Zhang Mancui is Corresponding author , Wang Fengzhi is the first author's paper "Long non-coding RNA ROR1-AS1 enhances colorectal cancer metastasis by targeting miR-375” After investigation, it was found that there was academic misconduct of writing and submitting agents. Zhang Mancui and Wang Fengzhi were dealt with as follows:

1. Criticize the whole hospital, and ordered to make a profound review and give sincere talks.

2. Cancel the promotion qualification for professional and technical positions for 4 years; cancel the application qualification for any level of projects for 5 years, and stop the subjects they undertake.

3. Return the layout fee and the scientific research reward for the paper involved.

(Notice link: http://www.umc.net.cn/NewsTopicDetail.aspx?PkId=22dede92-6738-417c-8d82-fe2ffd2df0cb)

2, Paper published by Dou Yan, the corresponding author of Xingtai People's Hospital of Hebei Province, is the corresponding author and Qiu Peng is the first author. "Long non-coding RNA TTN-AS1promotes themetastasis in breast cancer by epigenetically activate? DGCR8”, after investigation, it was found that there was an academic misconduct of third-party writing and submission. The relevant responsible persons will be dealt with as follows:

1. All authors will be given a warning and criticism and education on scientific research, and criticism will be reported.

2. The first author Qiu Peng's scientific research project application, project establishment, award evaluation, professional title promotion and other activities have been suspended for 5 years, and will be recorded in the scientific research integrity credit information system.

3. The first author Qiu Peng was disqualified as a nominee or recommender, nominee or referee, and review expert.

4. The corresponding author Dou Yan's scientific research project application, project establishment, award evaluation, professional title promotion and other activities have been suspended for 3 years, and will be recorded in the scientific research integrity credit information system.

5. Activities such as application, project establishment, award evaluation, and professional title promotion for one year are suspended.

(Notice link:

https://www.xtrmyy.cn/index/search/show/model/document/id/3365)

3, The paper "Circular RNA circ_0017247 promotes melanoma migration and invasion via targeting After investigation, miR-145" was found to be an academic misconduct of third-party institutions buying, selling, writing and submitting papers on behalf of others. The relevant responsible persons will be dealt with as follows:

1. For the corresponding author Chen Zhao: Scientific Research Integrity Warning and Criticism Education, the unit will report criticism, cancel the qualification to select master's supervisor and doctoral supervisor within 5 years, cancel the qualification to advance professional and technical positions within 5 years, cancel the qualification to apply for financial fund support projects within 5 years, cancel the qualification to obtain science and technology awards, apply for scientific and technological talents titles, etc. within 5 years, and cancel any qualification to evaluate excellence or pre-evaluation within 5 years.

2. For the first author Chen Zheng: Scientific research integrity warnings and criticism education, the unit reports criticism, cancels the qualification to promote professional and technical positions within 5 years, cancels the qualification to apply for financial fund support projects within 5 years, cancels the qualification to obtain science and technology awards, apply for scientific and technological talents titles, etc. within 5 years, and cancels any qualification to evaluate excellence or pre-evaluation within 5 years. 3. For other authors Kang Kang, Chen Si, Wang Sheng, Zhang Jing, Zhang Xiaoyun: Scientific Research Integrity Warning and Criticism Education, the unit will report criticism and cancel any qualifications for evaluation or evaluation within 5 years.

(Notice link: http://test.120.org.cn/newsdetail/13)

4. The paper "Caprin1 targeted by circularcirc_0000885 in the tumor progression of osteosarcoma" was published by Cangzhou People's Hospital of Hebei Province, Feng Qing, the corresponding author, Liu Xuanyi, the first author, and the co-first author, was published by the paper "Caprin1 targeted by circularcirc_0000885 in the tumor progression of osteosarcoma". After investigation, it was found that it was an academic misconduct of buying, selling, writing and submitting papers on behalf of others. Deal with relevant responsible persons:

1. For the first author Liu Xuanyi: Scientific research integrity warnings, unit criticism, cancellation of qualifications to undertake financial fund support projects within 5 years, and cancellation of 5 years of postgraduate enrollment qualifications.

2. For the co-first author Li Mian : Scientific research integrity warnings, unit criticism, cancellation of qualifications to undertake financial fund support projects within 3 years, and cancellation of 3 years of postgraduate enrollment qualifications.

3. For the corresponding author Feng Qing: A warning and admonishment talk about scientific research integrity, the unit reported criticism, and the qualification to undertake financial fund support projects within one year was cancelled, and the qualification to enroll in one year was cancelled.

4. For the second author Dong Bin: A warning and admonishment conversation about scientific research integrity, the unit reported criticism, and the qualification to undertake financial fund support projects within one year was cancelled, and the qualification to enroll in one year was cancelled.

(Notice link:

http://www.czrmyy.com/Html/News/Articles/2079.html)

5. Wei Ruojing, the first and corresponding author of Baoding City, Hebei Province, was the first and corresponding author. "Mir-155 affects renal carcinoma cell proliferation, invasion and apoptosis through regulatory GSK-3β/β-catenin signaling pathway”, after investigation, the paper submission did not use the original picture, which was an academic misconduct of image tampering.

1. Baoding First Central Hospital made the following treatments to the first and corresponding author Wei Ruojing: Scientific Research Integrity Warning and Administrative Warning and ; the papers involved are withdrawn; the relevant academic awards obtained by using scientific research breach of trust are revoked and the bonus is recovered; his postgraduate enrollment qualification is suspended within 3 years; personal application or application for science and technology plan projects (special projects, funds, etc.), science and technology awards, scientific and technological talent titles and professional and technical position promotions are suspended within 5 years.

2. Baoding First Hospital made the following treatment to the second author Zhang Chaohua: a warning and admonishment conversation on scientific research, a criticism, and suspended the qualifications for individual applications or application for science and technology plan projects (special projects, funds, etc.) within 3 years, and suspended the qualifications for assistant general practitioners to teach teachers for 2 years.

(Notice link:

http://www.bddhospital.com.cn/keyan/info903.html)

6, Jilin Provincial Cancer Hospital Gao Hong is the first author and Liu Chunzhi is the corresponding author "Long noncoding RNA UCA1 promotes proliferation and metastasis of thyroid cancer cells by sponging miR-497-3p”, after investigation, it was found that there were academic misconduct of third-party writing and submission. The relevant responsible persons will be dealt with as follows:

1. For the first author Gao Hong: The qualification to apply for financial funding support projects, science and technology awards, apply for scientific and technological talents titles and hospital scientific research awards will be cancelled, and the qualification to be an evaluation expert and recruit graduate students will be cancelled for 5 years, and the qualification to advance to the hospital's professional and technical titles and hospital evaluation and assessment will be cancelled for 2 years. The entire hospital will be criticized.

2. For the corresponding author Liu Chunzhi: The qualification to apply for financial fund support projects for five years, the qualification to apply for science and technology awards, the qualification to apply for science and technology talent titles and hospital research awards will be cancelled, the qualification to be an evaluation expert and the qualification to recruit graduate students will be cancelled, the qualification to be promoted for 1 year of hospital professional and technical titles and the qualification to evaluate the hospital for 2 years will be cancelled, and the entire hospital will be criticized. 3. Criticism of other authors Yang Jingyuan, Tong Lingxia, and Jin Hui: The whole hospital reported.

(Notice link:

https://www.jlszlyy.com/index/news/id/9634.html)

7, Fujian Cancer Hospital Zhang Jing is the corresponding author and Lin Dong is the first author's paper "Long non-coding RNA MIAT promotes non-small cell lung cancer progression by sponging miR-1246". After investigation, it was found that there was academic misconduct that tampered with research charts. The relevant responsible persons will be dealt with as follows:

1. The paper involved will be withdrawn and the reimbursed layout fee for the author of the paper will be recovered.

2. Corresponding author Zhang Jing: Criticize the hospital; revoke the host of Fujian Provincial Natural Science Foundation of China's project ( project number : 2017J01263), and refund the project surplus funds according to the original channel; suspend the qualification for professional title/position promotion and teaching professional title application within 1 year from the date of decision; suspend the application qualification for financially funded scientific research projects within 4 years; cancel the qualification for applying for or applying for provincial science and technology plan projects, science and technology awards, scientific and technological talent titles and review experts within 4 years; record it in the database of serious breach of trust in scientific research integrity.

3. For the first author Lin Dong: The hospital reported criticism, canceled the 2019 annual assessment excellent grade, suspended the qualification for professional title/vote promotion and teaching professional title application within 1 year from the date of decision, and suspended the application for financially funded scientific research projects within 4 years.

(Notice link:

http://www.fjzl.com.cn/ybkj/kyjx/202111/t20211110_13439.html)

8, Fujian Provincial Hospital Cui Tongjian is the corresponding author and Zheng Jianping is the first author's paper "Circular RNA circ-ABCB10 promotes non-small cell lung cancer proliferation and inhibits cell apoptosis through repressing KISS1”, after investigation, it was found that there were academic misconduct of fabricating research processes and subsidizing agents. The relevant responsible persons will be dealt with as follows:

1. For the first author Zheng Jianping: The application for professional title promotion is suspended once, and the application for science and technology plan projects will be restricted within 4 years.

2. For the corresponding author Cui Tongjian: The application for professional title promotion is suspended once, the application for science and technology plan projects is restricted within 4 years, and the recruitment of graduate students is suspended within 4 years.

(Notice link: http://www.fjsl.com.cn/info/22851.jspx)

9, First People's Hospital of Jining City, Shandong Province Zhang Yali is the corresponding author and Wang Xiuchun is the first author, "Resveratrol alleviates LPS-induced injury in human keratinocyte cell line HaCaT by up-regulation of miR-17". After investigation, it was found that there was an academic misconduct of tampering with data and fabricating research processes. The relevant responsible persons shall be dealt with as follows:

1. For the corresponding author Zhang Yali: the application qualification for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans within 5 years will be cancelled, the qualification for five years will be cancelled as a nominee, nominee, referee, review expert, etc., and the membership or membership of academic work institutions such as societies, associations, etc., and the instructed to contact the magazine as soon as possible to withdraw the article, and the administrative warning will be given.

2. For the first author Wang Xiuchun: Cancellation of application qualifications for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans within 5 years, cancellation of qualifications as nominees, nominees, referees, review experts, etc. for 5 years, recover the author's personal paper research awards and honorary titles, cancellation of membership or membership of academic work institutions such as societies, associations, etc., and delay promotion of one year higher-level professional and technical positions, and a party warning.

(Notice link:

http://www.jnrmyy.com/keyan/kxyj/gonggao/2021/1109/6411.html)

10, Li Yu, Shandong Jining First People's Hospital, Zhu Aidong is the first author, Chu Lifen and Ma Qiuju are the first authors, and "Re-published Long non-coding RNA H19 down-regulates miR-181a to facilitate endothelial angiogenic function”, after investigation, it was found that there was an academic misconduct of tampering with data and fabricating research processes. The relevant responsible persons will be dealt with as follows:

1. For the corresponding author Li Yu: The application qualification for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans within 5 years will be cancelled, the qualification for five years will be cancelled as a nominee, nominee or recommender, review expert, etc., the qualification for members or members of academic work institutions such as societies, associations, etc. will be cancelled, and the appointment of one year's senior professional and technical positions will be postponed. It is instructed to contact the magazine as soon as possible to withdraw the article, and the party warns.

2. For the first author Zhu Aidong: Cancellation of application qualifications for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans within 6 years, cancellation of qualifications as nominees, nominees, referees, review experts, etc., cancellation of membership or membership of academic work institutions such as societies, associations, etc., and delay promotion of 2 years of high school professional and technical positions; administrative warning.

3. A warning and admonishment to the first authors Chu Lifen and Ma Qiuju: a warning and admonishment to scientific research integrity, and the hospital reported criticism.

(Notice link:

http://www.jnrmyy.com/keyan/kxyj/gonggao/2021/1109/6411.html)

11, Qi Yuefeng, First People's Hospital of Jining City, Shandong Province, is the corresponding author, Zhang Lijuan is the first author, Wang Li, Guo Enyu is the paper "Silence of lncRNA CHRF protects H9c2 cells against lipopolysaccharide-induced injury via up-regulating microRNA-221”, after investigation, it was found that there was an academic misconduct of tampering with data and fabricating research processes. The relevant responsible persons shall be dealt with as follows:

1. For the corresponding author Qi Yuefeng: The application qualification for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans within 5 years will be cancelled, and the qualification for five years will be cancelled as a nominee, nominee or referee, and the evaluation expert will be cancelled. The qualification for members or members of academic work institutions such as societies, associations, etc. will be cancelled. The qualification for promotion to one year of high school will be suspended. It is instructed to contact the magazine as soon as possible to withdraw the article and be warned.

2. For the first author Zhang Lijuan: The application qualification for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans within 6 years will be cancelled, and the qualification for 6 years will be cancelled as a nominee, nominee, referee, review expert, etc. will be cancelled, and the membership or membership of academic work institutions such as societies, associations, etc. will be cancelled, and the promotion to a higher level professional and technical position for 2 years will be suspended. Administrative warning.

3. A warning and admonishment to the first authors of Wang Li and Guo Enyu: Scientific research integrity and admonishment, and the hospital reported criticism.

(Notice link:

http://www.jnrmyy.com/keyan/kxyj/gonggao/2021/1109/6411.html)

twelve, The paper published by Jining First People's Hospital of Shandong Province Wu Lian is the corresponding author, Sheng Cunjian is the first author, and Hu Fang is the first author, "Geniposide alleviates hypoxia-induced injury by down-regulation of lncRNA THRIL in rat cardiomyocytes derived H9c2 cells”, after investigation, it was found that there was an academic misconduct of tampering with data and fabricating research processes. The relevant responsible persons will be dealt with as follows:

1. Corresponding author Wu Lian: Cancellation of application qualifications for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans, etc. within 5 years, cancellation of qualifications as nominees or recommenders, nominees or referees, review experts, etc., cancellation of membership or membership of academic work institutions such as societies, associations, etc., and postponement of one year of senior professional and technical positions, and instructed to contact the magazine as soon as possible to withdraw the article, and an administrative warning.

2. For the first author Sheng Cunjian: Cancellation of application qualifications for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans within 6 years, cancellation of qualifications as nominees, nominees, referees, review experts, etc. for 6 years, recover the author's personal paper research awards and honorary titles, cancellation of membership or membership of academic work institutions such as societies, associations, etc., and delay promotion to the first-level professional and technical positions of 2 years, and administrative warning. 3. A warning and admonishment to the first author Hu Fang: a warning and admonishment to scientific research integrity, and a criticism was reported in the hospital.

(Notice link:

http://www.jnrmyy.com/keyan/kxyj/gonggao/2021/1109/6411.html)

13, The paper "MicroRNA-625-3p promotes the proliferation, migration and invasion of thyroid cancer cells by up-regulating astrocyte elevated gene 1”, after investigation, it was found that there was an academic misconduct of tampering with data. The relevant responsible persons shall be dealt with as follows:

1. For the corresponding author Xu Wei: The application qualification for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans within 5 years will be cancelled, the qualification for five years will be cancelled as a nominee, nominee or recommender, review expert, etc., the qualification for members or members of academic work institutions such as societies, associations, etc. will be cancelled, and the appointment of one year's senior professional and technical positions will be postponed. It is instructed to contact the magazine as soon as possible to withdraw the article, and the administrative warning will be given.

2. For the first author Fang Lei: The application qualification for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans within 6 years will be cancelled, and the qualification for 6 years will be cancelled as a nominee, nominee or referee, and the evaluation expert will be cancelled. He has obtained membership or membership of academic work institutions such as societies, associations, and has been promoted to a higher level professional and technical position for 2 years. A party warning will be issued.

3. For the author Kong Dedi, he canceled the application qualification for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans within 5 years, canceled the qualification for five years as a nominee, nominee, referee, review expert, etc., canceled the qualification for members or members of academic work institutions such as societies, associations, etc., and suspended the employment of one year higher-level professional and technical positions, and administrative warning.

(Notice link:

http://www.jnrmyy.com/keyan/kxyj/gonggao/2021/1109/6411.html)

14, Zheng Hongjian, the First People's Hospital of Jining City, Shandong Province, is the corresponding author, Shao Yuanxia is the first author, and Zhong Peng and Sheng Li are the first authors, and "Circular RNA circDENND2A protects H9c2 cells from oxygen glucose Deprivation-induced apoptosis through sponging microRNA-34a”, after investigation, it was found that there was an academic misconduct of tampering with data and fabricating research processes. The relevant responsible persons will be dealt with as follows:

1. For the corresponding author Zheng Hongjian: The application qualification for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans within 5 years will be cancelled, the qualification for five years will be cancelled as a nominee, nominee or referee, and the evaluation expert will be cancelled, and the membership or membership of academic work institutions such as societies, associations, etc. will be cancelled, and the appointment of one year's senior professional and technical positions will be postponed. It is instructed to contact the magazine as soon as possible to withdraw the article, and the administrative warning will be given.

2. For the first author Shao Yuanxia: the application qualification for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans within 5 years will be cancelled, the qualification for five years will be cancelled as a nominee, nominee or referee, and the evaluation expert will be cancelled, and the membership or membership of academic work institutions such as societies, associations, etc. will be cancelled, and the appointment of one year higher-level professional and technical positions will be postponed. Administrative warning.

3. The first authors Zhong Peng and Sheng Li: Scientific Research Integrity Warning, and the hospital reported criticism.

(Notice link:

http://www.jnrmyy.com/keyan/kxyj/gonggao/2021/1109/6411.html)

15, Li Hai, the first person in Jining City, Shandong Province, was the corresponding author, Hang Shiying was the first person, and Wang Xianghong was the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person in the first person miR-193b-3p”, after investigation, it was found that there was an academic misconduct of tampering with data and fabricating research processes. The relevant responsible persons shall be dealt with as follows:

1. For the corresponding author Li Hai: the application qualification for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans within 5 years will be cancelled, the qualification for five years will be cancelled as a nominee, nominee or referee, and the evaluation expert will be cancelled, and the membership or membership of academic work institutions such as societies, associations, etc. will be cancelled, and the promotion to one year of high school professional and technical positions will be delayed. It is instructed to contact the magazine as soon as possible to withdraw the article, and the administrative warning will be given.

2. For the first author, Hang Shiying: Cancellation of application qualifications for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans, etc. within 5 years, cancellation of qualifications as nominees or recommenders, nominees or referees, review experts, etc., cancellation of membership or membership of academic work institutions such as societies, associations, etc., and delay promotion of one year higher-level professional and technical positions, and administrative warning.

3. A warning and admonishment to the first author Wang Xianghong: a warning and admonishment to scientific research integrity, and the hospital reported criticism.

(Notice link:

http://www.jnrmyy.com/keyan/kxyj/gonggao/2021/1109/6411.html)

16, The paper "JMJD6-STAT3 Y705ph axis promotes autophagy in osteosarcoma cancer cells by regulating ATG”, after investigation, it was found that there was an academic misconduct of tampering with data. The relevant responsible persons shall be dealt with as follows:

1. For the corresponding author Lu Xin: The application qualification for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans within 5 years will be cancelled, the qualification for five years will be cancelled as a nominee, nominee or referee, and the evaluation expert will be cancelled, and the membership or membership of academic work institutions such as societies, associations, etc. will be cancelled, and the promotion to one year of high school professional and technical positions will be delayed. It is instructed to contact the magazine as soon as possible to withdraw the article, and the administrative warning will be given.

2. For the first author Wang Kun: The application qualification for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans within 5 years will be cancelled, and the qualification for five years will be cancelled as a nominee, nominee or referee, and the evaluation expert will be cancelled. The membership or membership of academic work institutions such as societies, associations, etc. will be cancelled, and the appointment of one year higher-level professional and technical positions will be postponed. The party warns.

3. For the first author Du Baoyin, the application qualification for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans within 5 years will be cancelled, the qualification for five years will be cancelled as a nominee, nominee, referee, review expert, etc., the membership or membership of academic work institutions such as societies, associations, etc., and the promotion to one year higher-level professional and technical positions will be suspended. Administrative warning.

4. The author Xu Bin: Scientific Research Integrity Warning, and the hospital reported criticism.

(Notice link:

http://www.jnrmyy.com/keyan/kxyj/gonggao/2021/1109/6411.html)

17, The paper "Negative feedback of NF-κB signaling by long noncoding RNA MALAT1 controls? lipopoly saccharide-induced Inflammation injury in human lung fibro -blasts WI-38". After investigation, it was found that there was an academic misconduct of tampering with the paper data.The relevant responsible persons will be dealt with as follows:

1. The corresponding author Men Xuelin: Scientific Research Integrity Warning, Criticism; Cancellation of the qualification to apply for or apply for science and technology plan projects, science and technology rewards, and scientific and technological talent titles within 5 years; cancellation of the qualification to be nominated or recommended, nominated or recommended, review expert within 5 years; suspend application for graduate instructor qualification for five years; order to withdraw the article immediately; and be warned.

2. For the first author Zhu Wei: Conduct a warning and admonishment conversation on scientific research, and report criticism; cancel the qualification to apply for or apply for science and technology plan projects, science and technology rewards, and scientific and technological talent titles within 5 years; cancel the qualification to be nominated or recommended, nominated or recommended, review expert within 5 years; order to withdraw the article immediately; be warned.

(Notice link:

http://jndsyy.cn/Front/Public/Article/NewsContent?id=7222)

18, Li Yongmei, an employee of the Yantai Traditional Chinese Medicine Hospital of Shandong Province, is the corresponding author, Mou Zhongyan is the first author, and Wang Yan is the first author, and Wang Yan is the first author, "Brazilein induces apoptosis and G1/G0 phase cell cycle arrest by up-regulation of miR-133a in human vestibular schwannoma cells”. After investigation, it was found that there was an academic misconduct of writing and submitting on behalf of others. The following treatments were made to the corresponding author Li Yongmei, the first author Mou Zhongyan, and the first author Wang Yan: the application for scientific research projects and scientific research award qualifications at all levels within 5 years will be suspended, and the qualifications such as promotion to positions will be cancelled for 5 years will be recorded in the scientific research integrity information system, and the entire hospital will report criticism.

(Notice link: http://www.ytzyy.cn/news/1050.html)

19, Zhang Huanyi, Tai'an Central Hospital of Shandong Province, is the corresponding author, and Guo Zhongxiu and Zhou Dao are the first authors. "Suppression of microRNA-101 attends hypoxia-induced myocardial H9c2 cell injury by targeting DIMT1-Sp1/survivin pathway", after investigation, it was found that there were academic misconducts of tampering with pictures and data and writing papers. The relevant responsible persons will be dealt with as follows:

1. For the corresponding author Zhang Huanyi: the application qualification for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans within 5 years will be cancelled; the qualification for promotion of professional and technical positions will be cancelled within 5 years will be cancelled; the qualification for being nominated or recommended, nominated or recommended, review expert will be cancelled within 5 years; the document will be recorded in the scientific research integrity and breach of trust; the scientific research admonition and admonition will be given, and the entire hospital will be criticized.

2. For the first author Guo Zhongxiu: the science and technology plan projects and professional titles obtained by using scientific research breach of trust will be revoked, the reimbursement of the layout expenses will be recovered, and the paper rewards will be doubled; the application qualification for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans will be cancelled within 5 years; the qualification for promotion of professional and technical positions will be cancelled within 5 years; the qualification for being nominated or recommended, nominated or recommended, review expert will be cancelled within 5 years; the qualification will be recorded in the scientific research integrity and breach of trust; the scientific research integrity and integrity will be admonished and criticized by the whole hospital.

3. For the first author Zhou Development: the title of scientific and technological talents obtained by using scientific research breach of trust; the application qualification for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans within 5 years was cancelled; the qualification for promotion of professional and technical positions within 5 years was cancelled; the qualification for being nominated or recommended, nominated or recommended, review expert within 5 years was cancelled; the qualification for scientific research integrity was warned and criticized by the whole hospital.

(Notice link: https://www.taishanyy.com/kygl/info_393.aspx?itemid=12189)

20, Wu Xingguo, the corresponding author of Tai'an Central Hospital of Shandong Province, Laiwu Maternal and Child Health Hospital (now Jinan Second Maternal and Child Health Hospital), Zou Aixia, and Liu Rui, Zoucheng People's Hospital, are the first authors. "Long non-coding RNA MALAT1 is up-regulated in ovarian cancer tissue and promotes SK-OV-3 cell proliferation and Invasion”, after investigation, it was found that there were academic misconducts such as fabricating data, tampering with pictures and data, and writing papers.

1. Tai'an Central Hospital made the following treatment to the corresponding author Wu Xingguo: revoke the title obtained by using scientific research breach of trust; cancel the application qualification for scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans within 5 years; cancel the promotion and appointment qualification for professional and technical positions within 5 years; cancel the qualification for being nominated or recommended, nominated or recommended, review expert within 5 years; record it into the scientific research integrity breach of trust; scientific research admonition talk, and the entire hospital reported criticism.

2. Laiwu Maternal and Child Health Hospital (now Jinan Second Maternal and Child Health Hospital) made the following treatment to the first author Zou Aixia: revoke the relevant academic evaluations, honorary titles, etc. obtained by using scientific research breach of trust, and collect the reimbursed layout fees and bonuses; cancel the application qualification for scientific research projects, scientific research awards, scientific talent plans, etc. within 5 years; cancel the promotion and appointment qualification for professional and technical positions within 5 years; cancel the qualification for being nominated or recommended, nominated or recommended, review expert within 5 years; record it into the scientific research integrity breach of trust; scientific research admonition and admonition talk, and the entire hospital reported criticism.

3. Zoucheng People's Hospital made the following handling against Liu Rui, the tied first author: administrative demerit, and the annual qualification for evaluation of the first place and professional title promotion was cancelled.

(Notice link: https://www.taishanyy.com/kygl/info_393.aspx?itemid=12189)

21, paper "MiR-101 reduces cell proliferation and invasion and enhances apoptosis in endometrial cancer via regulatory PI3K/Akt/mTOR" was published by Jinan Maternal and Child Health Hospital, Shandong Province, as the corresponding author and Zhang Suxia, as the first author. After investigation, it was found that there was an academic misconduct of tampering with data. The relevant responsible persons shall be dealt with as follows:

1. For the corresponding author Zhu Ping: order the author of the article to withdraw the article; cancel the qualification for promotion and appointment of professional and technical positions within 5 years; cancel the qualification for being nominated or recommended, nominated or recommended, review expert within 5 years; cancel the qualification for applying for or applying for science and technology plan projects (special projects, funds, etc.), science and technology awards, and scientific and technological talent titles within 5 years; record it into the scientific research integrity and dishonest file; conduct a warning and admonishment conversation on scientific research integrity, and the entire hospital shall report and criticize it.

2. For the first author Zhang Suxia: order the author of the article to withdraw the article; collect the hospital bonus; cancel the qualification for promotion and appointment of professional and technical positions within 5 years; cancel the qualification for being nominated or recommended, nominated or recommended, review expert within 5 years; cancel the qualification for applying for or applying for science and technology plan projects (special projects, funds, etc.), science and technology awards, and scientific and technological talent titles within 5 years; record it into the scientific research integrity and dishonest file; conduct a warning and admonishment conversation on scientific research integrity, and the entire hospital reported criticism.

3. For the second author Wang Min: the qualification to promote and hire professional and technical positions within 5 years was cancelled; the qualification to be a nominee, nominee, referee, and review expert within 5 years was cancelled; the qualification to apply for or apply for science and technology plan projects (special projects, funds, etc.), science and technology awards, and scientific and technological talent titles were cancelled within 5 years; it was recorded in the scientific research integrity and breach of trust; conduct a warning and admonishment conversation on scientific research integrity, and the entire hospital reported criticism.

4. For the third author Li Qirong: the qualification to be a nominee, nominee, referee, review expert within 5 years; the qualification to apply for or apply for science and technology plan projects (special projects, funds, etc.), science and technology awards, and scientific and technological talent titles within 5 years; it is recorded in the scientific research integrity and breach of trust; conduct a warning and admonishment conversation on scientific research integrity, and the entire hospital reported criticism.

(Notice link: http://www.fybjy.com.cn/about/2480.html)

22, The paper "MiR-410 affects the proliferation and apoptosis of lung cancer A549 cells through regulation of SOCS3/JAK-STAT signaling pathway" was published by Yantai Yeda Hospital of Shandong Province. After investigation, it was found that there was an academic misconduct of writing and submitting on behalf of others. Yuan Fenglong, Li Ming and Zheng Rui were dealt with as follows: contact the magazine independently within 30 days to withdraw the papers involved; a warning and admonishment talk on scientific research integrity; public criticism within the hospital, and the application qualification for professional title promotion, scientific and technological talents, scientific and technological projects and scientific and technological awards was cancelled for 5 years.

(Notice link:

https://www.yedayy.com/content/595/1572/1.html)

23, paper "Mir-218 promotes apoptosis of U20S osteosarcoma cells through targeting BIRC5" published by Zhangqiu District People's Hospital, Jinan City, Shandong Province, "Mir-218 promotes apoptosis of U20S osteosarcoma cells through targeting BIRC5". After investigation, it was found that there was an academic misconduct of fraud in the paper. The relevant responsible persons shall be dealt with as follows:

1. For the corresponding author Gao Jianfen: the qualification to apply for professional title promotion, scientific and technological talents, scientific and technological projects and scientific and technological awards for 5 years will be cancelled; the scientific research integrity warnings will be given and criticized by the hospital; the qualification of members or members of academic groups such as societies, associations or research associations will be cancelled; the information system for credit is recorded in the scientific research integrity information system.

2. For the first author Wang Dezhang: cancel the application qualification for professional title promotion, scientific and technological talents, scientific and technological projects and scientific and technological awards for 5 years; recover the paper bonus; give warnings and exhortations to scientific research integrity, and criticize the institute; cancel the membership or membership of academic groups such as associations, associations or research associations; record it in the scientific research integrity credit information system.

3. For the second author Jing Shenfeng: recovering the paper bonus, giving a warning to scientific research integrity, and criticism from the hospital.

(Notice link:

http://www.zqrmyy.net/a/tupianxinwen/20211104/2904.html)

24, Ge Hanming, the Third Hospital of Xi'an, Shaanxi Province, is the first corresponding author, Jia Fubao, the first author of Shanxian Central Hospital of Shandong Province, and Mou Lei, the co-first author (second place). "Protective effects of ginsenoside Rb1 on H2O2-induced oxidative Injury in human endothelial cell line (EA.hy926) via miR-210” After investigation, it was an academic misconduct of a third-party writing and submission agency.

1. Xi'an Third Hospital made the following treatments to the responsible person Ge Hanming: warning; conduct a speech on scientific research integrity warning; personal written inspection and criticism; delay application for professional and technical position promotion qualification for 5 years; stop applying for all categories of scientific research projects for 5 years; revoke scientific and technological rewards and recover bonuses; deduct personal performance for 1 month; order to withdraw the manuscript.

2. Shandong Shan County Central Hospital made the following treatment to the responsible person Jia Fubao: ordering the revocation, a warning and admonishing conversation on scientific research integrity, and criticizing the entire hospital, canceling the qualification for promotion and appointment of professional and technical positions within 5 years, canceling the qualification for applying for or applying for science and technology plan projects (special projects, funds, etc.), science and technology awards, and scientific and technological talent titles within 5 years; canceling the qualification for being nominee, nominee, nominee, review expert, etc. within 5 years, and recording it in the scientific research integrity and dishonest file.

3. Rizhao Traditional Chinese Medicine Hospital in Shandong Province made the following treatment to the responsible person Mou Lei: a warning and admonishment talk on scientific research integrity, the entire hospital reported criticism, fined 50,000 yuan, cancelled the qualification to promote professional and technical positions within one year, cancelled the qualification to apply for or apply for science and technology plan projects (special projects, funds, etc.), science and technology awards, and scientific and technological talent titles within five years, cancelled the qualification to be nominated or recommended, nominated or recommended, review expert, etc. within five years, and recorded it in the scientific research integrity and dishonest file.

(Notice link:

http://www.xa3yuan.com/detaile/21110815kGP1W)

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