Since the outbreak of the new coronavirus pneumonia, some new special symptoms and complications have appeared in children. In addition, the superimposed epidemic of influenza viruses and new coronaviruses, which are both transmitted through respiratory droplets and contact, has

Since the outbreak of the new coronavirus pneumonia, some new special symptoms and complications have appeared in pediatric patients. In addition, the superimposed epidemic of influenza virus and the new coronavirus, which are both transmitted through respiratory droplets and contact, has given rise to Epidemic prevention, control and treatment in children pose more complex challenges.

Since the development of children's organs and systems is immature, especially the liver and kidney's decomposition, metabolism, and excretion functions of drugs are not yet perfect, their tolerance to drugs is far less than that of adults. Therefore, early intervention for influenza virus and novel coronavirus infection in children, especially the combination of traditional Chinese and Western medicine in the mild stage, is of great significance to the prognosis of the disease.

Chinese Medical Association Magazine " Chinese Medical Information Herald " and Sunflower Pharmaceutical Group held the "Integrated Traditional Chinese and Western Medicine·Worry-Free Child Care" Children's Influenza Integrated Traditional Chinese and Western Medicine from 9:00 to 11:00 on June 19 Diagnosis and treatment interpretation and children new coronavirus pneumonia treatment case sharing public welfare science lecture, exploring the clinical disease characteristics and treatment experience of children's influenza and children's new coronavirus infection cases. The

conference was broadcast live simultaneously on 7 major platforms (Chinese Medical Information Herald, Physician's News, Quanxueyuan, Toutiao, , Zhihu, , Weibo, and Kangxun.com), with more than 150,000 online viewers.

The conference was hosted by Professor Ma Rong, Honorary Chairman of the Pediatric Branch of the Chinese Society of Chinese Medicine. The first guest speaker was Professor Wang Xuefeng from the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine. Professor Wang discussed influenza recent development trends and the mutual reference between Chinese and Western medicine. Regarding the treatment of influenza, we will provide you with the "Expert Consensus Interpretation of Integrated Traditional Chinese and Western Medicine Prevention and Treatment of Influenza in Children", which reminds us that influenza is a major disease that threatens human health, and hospitalized patients are the population with a heavier burden of influenza. At the same time, existing anti-influenza drugs have problems such as short treatment time window, inaccurate efficacy in hospitalized patients with influenza, inability to effectively anti-inflammatory reduce the occurrence of hospitalization and complications, and increased drug resistance. However, Chinese patent medicine pediatric lung cancer Rekechuan Oral Liquid can shorten the time to reduce fever, relieve symptoms such as cough, and improve the efficiency of treatment. It can be used as a treatment drug for influenza, especially for hospitalized patients with influenza.

Children's Feire Kechuan Oral Liquid is also the country's first government reserve drug for the treatment and prevention of children H1N1 influenza . It has been included in multiple guidelines/consensus recommended influenza treatment drugs, and is included in the "Expert Consensus on the Prevention and Treatment of Influenza in Children with Integrated Traditional Chinese and Western Medicine" The main symptoms of TCM treatment of "heat poison attacking the lungs" are high fever, cough, sticky phlegm, difficulty in spitting up phlegm, thirst, sore throat, and red eyes. Children's Lung Heat Cough and Chuan Oral Liquid is also recommended. Professor Wang pointed out that for Early intervention for influenza, especially the combination of traditional Chinese and Western medicine in the mild stage, is also of great significance to the prognosis of the disease.

Professor Yu Jian, Director of the Department of Traditional Chinese Medicine, Children's Hospital of Fudan University, Shanghai, shared "Clinical Characteristics of Children's New Coronavirus Infection and Discussion on Shanghai's Experience in Collaborative Diagnosis and Treatment of Traditional Chinese and Western Medicine". The lecture provided a detailed analysis of the current situation and characteristics of children's new coronavirus infection. Yu Jian The professor said that the infection rate of children in the early stage of the COVID-19 epidemic was 2% ~ 9.0%. With the spread of the Omicron strain, the infection rate in children increased significantly compared with the early stage of the COVID-19 epidemic. A small number of severe or even critical cases of COVID-19 with underlying diseases and low immunity appeared in local outbreaks in Shanghai. Severe and critical illnesses include accidental injuries, complex congenital heart disease, organ transplantation, tumor radiotherapy and chemotherapy, etc., and those with low immune function (liver and kidney transplantation, etc.) have a significantly longer nucleic acid negative turn-around time.

The TCM syndrome characteristics and core pathogenesis of pediatric COVID-19 patients are basically the same as those of adults. The treatment refers to the TCM treatment plan for adults, combined with the clinical symptoms of pediatric patients and the physiological characteristics of children, and is used appropriately based on syndrome differentiation. Children can choose to use Chinese patent medicines for syndrome differentiation. Prescriptions such as Maxing Shigan Decoction and other Chinese patent medicines have played a good role in the treatment of the new coronavirus epidemic. At the same time, based on the actual treatment experience in Shanghai, we summarized the traditional Chinese and Western medicine and prevention methods for treating asymptomatic , mild and ordinary infections, and combined with external treatment of traditional Chinese medicine: massage techniques and dosage form dual treatment for children with new coronavirus infection.

Professor Yu Jian also shared two actual cases of children with new coronavirus in Shanghai. A detailed analysis of the effects of treating Shanghai children with new coronavirus with TCM heat toxin pulmonary syndrome after using Maxing Shigan Decoction and other traditional Chinese medicine prescriptions. The majority of doctors provided valuable experience.

Deputy Dean of the Guangzhou Institute of Respiratory Health of Guangzhou Medical UniversityProfessor Yang ZifengAs an important member of the academician Zhong Nanshan team, he told everyone about the prevalence and treatment of respiratory virus infections in the post-COVID-19 era. The lecture not only talked about the continuous mutation of the new coronavirus The reason also shows that the new coronavirus mutation is easy to occur in cold and cold areas, and the southern flu appears frequently, so traditional Chinese medicine treatment can be more involved. It was mentioned in the

meeting that a large number of clinical trials have been conducted on some drugs for the treatment of COVID-19 and influenza, including Children's Feire Cough and Cough Oral Liquid, Children's Feire Oral Liquid. The prescription of this medicine is derived from "Typhoid Miscellaneous" written by the medical saint Zhang Zhongjing The classic famous prescription in "Disease Treatise" - Maxing Shigan Decoction + Baihu Decoction, was later combined with Yinqiao Powder by Professor Zhao Xinbo, one of the four famous pediatric doctors in modern my country. It is mainly targeted at wind-heat attacking the lungs and heat poison attacking the lungs. The clinical manifestations are fever, dry throat and pain, cough, etc.

In the mechanism study, Children's Feire Kechuan Oral Liquid has dual anti-viral and anti-inflammatory effects. It has a strong inhibitory effect on the influenza virus ERK pathway and IFN pathway. It also inhibits excessive immune inflammation induced by influenza and improves Influenza virus infection causes inflammatory response . It has an inhibitory effect on the proliferation of new coronavirus in vitro. At the same time, Children's Feire Kechuan Oral Liquid can achieve the effect of inhibiting the virus through the dual effects of inhibiting virus proliferation and inhibiting the overexpression of inflammatory factors.

As the COVID-19 epidemic becomes complex and ever-changing, how to prevent and control the epidemic has increasingly become a problem that we need to explore. In March 2022, The World Health Organization released the "Report of the World Health Organization Expert Evaluation Meeting of Traditional Chinese Medicine for the Treatment of COVID-19", encouraging Member states are considering China’s integrated traditional Chinese and Western medicine model for the treatment of COVID-19. Children’s organs and systems are immature, and the influenza virus and novel coronavirus are both spread through respiratory droplets and contact. Therefore, children with mild symptoms are unlikely to be treated well. Interventions combining traditional Chinese and Western medicine at different stages have increasingly highlighted their important value.