people with this blood type may have higher risk of early stroke: study.

A new study found that people's blood type may be a factor in their early stroke risk.

researchers studied the genetic profiles of people who may have strokes before the age of 60 and their likelihood of risk for early onset stroke (EOS). The study was published in the journal Neurology.

https://n.neurology.org/content/early/2022/08/31/WNL.0000000000201006

The human blood types are divided into four types: A, B, AB, and O. Is it related to health? After examining 48 studies on genes and ischemic strokes, the researchers found that some blood types do have relatively high chances of stroke.

A research team led by Dr. Kitner from the University of Maryland Medical Center (UMMC) in the United States analyzed 48 different studies on EOS in people aged 18-59. A genetic difference between 17,000 stroke patients and 600,000 healthy people was found to be associated with a high risk of early onset stroke in a specific genetic variant, which in turn determines the human blood type.

The so-called blood type refers to antigen on the surface of red blood cells, which are divided into type A antigen and type B antigen. A antigen is type A blood, and B antigen is B blood ; some people's red blood cells also have AB antigen, which is type AB blood, and some people's blood cells have no antigen on the surface of O blood .

After searching for genetic variations across the genome and the study group, researchers found that there were significant genetic differences between patients who experienced stroke and those who did not. Disparities were particularly observed in genes of ABO blood type.

Red blood cell surface antigen is type A blood, B antigen is type B blood, two antigens AB are type AB blood, and non-antigens are type O blood.

results show that there is a "significant association" between EOS and the chromosomal portion of the gene that determines the blood type.

Specifically, researchers found that people with type A blood were 16% more likely to have a stroke before the age of 60 compared to people with other blood types, while people with type O blood were least likely to have an early stroke, with an average stroke rate of about 12% lower than other blood types (B, AB). However, after the age of 60, the difference in stroke risk between different blood types "disappeared".

Although this conclusion sounds unfavorable to blood type A, the risk is relative. People with type O blood type who are not prone to premature stroke are also more likely to experience severe bleeding events. "We still don't know why type A blood poses a higher risk, but it may be related to platelet and blood vessel lining cells and other circulating proteins. More follow-up studies are clearly needed to elucidate the mechanism of increased stroke risk."

Meanwhile, the study also increases the risk factors scientists have already understood for heart disease uncontrollable, such as the genetic factors that lead to a human blood type. From a medical point of view, understanding the genetic basis behind stroke can “provoke discussions about drugs or other intervention strategies that reduce arterial or venous thrombosis.

also reminds those who may be genetic characteristics of higher strokes to make healthier lifestyle changes.

According to Centers for Disease Control and Prevention (CDC), stroke is one of the leading causes of death in the United States, with one stroke every 40 seconds and one death every 3.5 minutes. Nearly 90% The stroke is ischemic stroke, where the blood clots prevent blood from reaching the brain.

The highest stroke mortality rate in the southeastern United States

https://www.cdc.gov/stroke/facts.html

Apart from heredity and blood type, age is another factor that increases the risk of stroke. CDC warns that the risk of stroke doubles every 10 years after the age of 55. While strokes occur most often in people aged 65 and older, one in seven strokes occur in people aged 15-49.

In addition, gender can also affect stroke. A 2022 review report states that women are more likely to suffer from stroke than men and then bear disproportionate burden of disability and death.

Another study showed that young women aged 35-45 had a 44% higher risk of ischemic stroke than men of the same age. The CDC explains that women have a higher risk of stroke due to pregnancy and use of contraceptives.

Although this new study shows that there is a strong genetic factor between blood type and stroke, Dr. Kitner said, "Don't worry too much about blood type. Overall, it's a relatively smaller risk factor." This may be surprising, but it does, about 80% of strokes are preventable.

Currently, people can reduce the risk of stroke by studying factors that are different from blood types but can actually be controlled.

They include building better living habits such as exercise, reducing salt intake, adding more fruits and vegetables to your diet and quitting smoking, and sticking to a healthy diet of whole grains, fish and nuts.

study shows that exercising at least 2.5 hours a week within 3 months after stroke can improve a person's health and overall quality of life. Even walking around for 10 minutes a day is a bigger difference than doing nothing.

consensus is the key to maintaining healthy ways and early intervention.

People With This Blood Type May Have Higher Risk Of Early Stroke: Study

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