Author: Wang Kangwei
Singapore study points out that the immunity of elderly people who receive two doses of vaccine is weaker than that of young people, but this difference can be reduced after receiving the additives. (Archives)
Duke—A joint study conducted by the National University of Singapore School of Medicine and the National Center for Infectious Diseases of Singapore found that compared with other coronavirus strains and other coronaviruses, Omickron strain can better avoid the human immune barrier and cause more people to get infected. But this also gives more vaccinated people a mixed resistance and better coexist with the coronavirus.
Singapore research points out that compared with other coronaviruses, the Omickron variant strain can better avoid antibodies, and the waves of peaks caused by the vaccination population can better coexist with the coronavirus.
Another study pointed out that the immunity produced by elderly people after receiving two doses of basic coronavirus vaccine is weaker than that of younger people, but this difference can be reduced after receiving the additives.
Duke — Research jointly conducted by the National University of Singapore School of Medicine and the National Center for Infectious Diseases of Singapore found that compared with other coronavirus strains and other coronaviruses, the Omickron strain can better avoid the human immune barrier.
Research points out that the Omickron strain will cause more people to get infected, but it will also allow more vaccinated people to better coexist with the coronavirus. (Duke - Official website of National University Medical College)
Professor Wang Linfa explained that the variant strain of the coronavirus "stand out" under the pressure of natural selection and has a different evolutionary path from other coronaviruses that are circulating among animals and are less "hard" in competition.
Professor Lai Jianwen, director of the Ministry of Infectious Disease Research Training and Education of the National Infectious Disease Center of Singapore, believes that the high infectivity of Omickron allows more people to have hybrid immunity, that is, people obtain antibodies through infection and vaccination, and obtain better protection when they encounter re-infection, and obtain immunity through the mucosa of the nose and throat to block the invasion of the virus. Previous studies have shown that after inoculation, antibody cells that survived for a long time - T cells were found in the mucosa of people who were infected with the disease.
study also pointed out that people who have been vaccinated and have an additional supplement have a milder condition after the epidemic, and the probability of 's lung infection and oxygen supply is lower.
It is worth noting that studies have also shown that people who have been vaccinated with the Pfizer vaccine and are infected with the virus have an immune response throughout their bodies than those who have been vaccinated but have not been infected.
study also pointed out that people who have been vaccinated and have a milder condition after the epidemic, and the probability of lung infection and oxygen supply is lower. (Photo by He Jiajun) Wang Linfa, who leads the National Epidemic Prevention and Response Research Program (PREPARE), said: "This research result is very important and will guide the future anti-epidemic response, including the development of better and more extensive protection vaccines."
elderly people who are vaccinated with additives can alleviate the lack of immunity
Another survey conducted by researchers at the Infectious Disease Laboratory of Singapore Institute of Science and Technology (A*STAR) found that the elderly people have poor immune response after receiving two doses of basic vaccines, and the immunity gap after receiving additives can help make up for the situation of immunity gap.
study tracked 312 medical personnel and elderly people who received two doses of the Pfizer vaccine and found that most people after vaccination can produce strong B cell and T cell immune responses to the original virus.
However, the subjects' response to delta and Omickron strains was weak, indicating that it is still possible to get infected after inoculation. Another 30% of the subjects' immune response began to weaken six months after receiving the second dose of the vaccine.
researchers also observed that those over 60 years old have an immune response after vaccination of less than those under 60 years old, they will also develop an immune response more slowly. However, after vaccination with the additives, they can strongly improve the immune and T cell response.
researchers analyzed that poor immune responses in elderly people may be related to immune aging, which causes them to still get infected after vaccination. "This shows that for vaccinated people, especially the elderly, it is still crucial to get the additives to obtain protection against the coronavirus strains that are spread in the population."
In addition to the New Research Infectious Disease Laboratory, the Singapore Immunology Network, Duke-National University Medical School and the National Center for Infectious Diseases also participated in the study.
