treats the recent new coronavirus infection. According to traditional Chinese medicine, it is necessary to distinguish the syndrome type. The simplest one is whether it belongs to wind-cold or wind-heat , in order to effectively treat it. In fact, from the perspective of myself and the people around me, it is basically due to exogenous wind, cold, and dampness. The most typical symptom is being afraid of cold, or even shivering when cold.
Wind-cold stagnation in the lungs: It is caused by the external attack of wind-cold evil and the loss of lung qi. Symptoms include severe aversion to cold, mild fever without sweating, headache and body aches, nasal congestion and runny nose, cough and thin white phlegm, no thirst or preference for hot drinks, and thin white fur. The treatment method should be mainly pungent and warm to relieve symptoms.
Wind-heat attacks the lungs: It is caused by the evil attack of wind-heat on the surface and the loss of harmony of lung qi. Symptoms include severe fever, slight nausea, head swelling and pain, sweating, sore throat, cough, sticky or yellow phlegm, nasal congestion and yellow discharge, thirsty drinkers, red tip of tongue, thin white and yellowish coating. The treatment method should be mainly pungent and cool to relieve symptoms.
For COVID-19 positive patients, if the syndrome is wind-cold and dampness stagnation in the lungs, Tongxuanlifei Pills , Ganmao Qingre Granules , Jingfang Granules, etc. can be used. Judging from clinical observation, better results can be obtained.
Tongxuan Lifei Pills
Tongxuan Lifei Pills, the main ingredients are Perilla leaves, Pediculus, platycodon, bitter almonds, ephedra, tangerine peel, pinellia system, Poria , Citrus aurantium stir-fried, skullcap, licorice . Relieves external symptoms, dispels cold, relieves lung inflammation and relieves cough. It is used for wind-cold cold, cough, difficulty in expectoration, fever, aversion to cold, , stuffy nose and runny nose, headache without sweating, and sore limbs.
In the prescription, perilla and ephedra are warm and pungent powders, which can dispel wind and cold, relieve sweating, relieve the lungs and relieve asthma, and together they are monarch drugs; Pediculus and bitter almonds reduce qi, resolve phlegm and relieve asthma, Platycodon expanses the lungs, resolves phlegm and relieves the throat. The combination of these three medicines can restore the lungs' ability to relieve inflammation, and tangerine peel and pinellia dryness. Dampness and phlegm , Poria cocos strengthens the spleen and exudes dampness, eliminates the source of phlegm, and is a ministerial drug together; Scutellaria baicalensis clears and purges lung heat, prevents external evils and internal depression from transforming heat, and prevents ephedra, pinellia and other excessive warming and dryness. Citrus aurantium regulates qi and makes the qi flow, phlegm transforms and body fluids are restored, and together they are adjuvant drugs; licorice reduces phlegm and relieves cough, and harmonizes various other drugs.
All the medicines are combined and have the effect of resolving superficial cold, dispersing cold, clearing the lungs and relieving cough. This medicine relieves the surface and dispels cold, clears the lungs and relieves coughs. It is a good medicine for treating wind-cold colds and coughs. It can effectively deal with symptoms such as poor expectoration, fever and chills, nasal congestion and runny nose, headache without sweating, and limb aches.
Modern pharmacological research shows that Tongxuanlifei Pills have the following effects: ① It has antitussive effect. It can prolong the incubation period of guinea pig cough caused by citrate and reduce the number of coughs. It can prolong the incubation period of cough in mice caused by ammonia water and reduce the number of coughs within 2 minutes. It has an inhibitory effect on guinea pig cough caused by electrical stimulation. ②It has the effect of eliminating phlegm. It can increase the amount of sputum produced in the trachea of rats. ③Has antiasthmatic effect. It can prolong the latency period of wheezing in guinea pigs caused by histamine phosphate and acetylcholine chloride.
④ has antipyretic effect. It has an antipyretic effect on the fever in rats caused by Escherichia coli endotoxin . ⑤Has anti-inflammatory effect. It can inhibit the swelling of rats' feet caused by egg white and inhibit the increase of abdominal capillary permeability in mice caused by acetic acid. ⑥ Has antibacterial and antiviral effects. It has a therapeutic effect on pneumonia caused by influenza virus infection in mice.
Ganmao Qingre Granules
Ganmao Qingre Granules are composed of Schizonepeta , mint, Fangfeng, Bupleurum , perilla leaves, kudzu root, platycodon, bitter almond, Angelica dahurica , Kudidin , Reed root . Disperses wind and cold, relieves surface heat and clears away heat. It is used for colds, headaches and fever, aversion to cold and body pain, runny nose, cough and dry throat.
Ganmao Qingre Granules are recorded in the " Pharmacopoeia of the People's Republic of China ". They have the effects of dispelling wind, dispersing cold, clearing away heat, relieving symptoms , and are often used for the prevention and treatment of influenza. In the prescription, Schizonepeta paniculata has a pungent aroma and is good at dispersing wind, so it is a monarch medicine; Fangfeng and Perilla leaves dispel wind and cold, Mint and Bupleurum dispel wind and heat, Pueraria lobata relieves muscle and reduce fever, produces body fluid and quenches thirst, and is a ministerial drug; Platycodon and bitter almond soothes lung qi, resolves phlegm and relieves cough, Angelica dahuricae relieves surface wind and relieves pain, clears heat and detoxifies, and reed root clears away heat, promotes body fluid and quenches thirst, and is used as an auxiliary medicine.All medicines are used together to dispel wind, clear away heat and relieve external symptoms.
A study published in " World Traditional Chinese Medicine ", "The mechanism of action of Ganmao Qingre Granules in preventing and treating new coronavirus pneumonia based on network pharmacology and molecular docking" shows that: through the Internet Pharmacology, the research found that there are 152 chemical components in Ganmao Qingre Granules. These components can target a total of 293 target proteins, of which there are 59 targets related to new coronavirus , indicating that Ganmao Qingre Granules can treat new coronavirus pneumonia in a multi-component and multi-target manner. The specific performance of
is as follows: by regulating the expression of cell proliferation, , apoptosis-related targets, and inflammation-related targets, it inhibits the release of virus , anti-inflammation, and antioxidant, and inhibits the inflammatory mediator storm and excessive immune response in patients with new coronavirus pneumonia.
Jingfang granules
Jingfang granules are composed of Schizonepeta , Fangfeng, Qianghuo, Duhuo, Bupleurum, Qianhu, Chuanxiong, Citrus aurantium, Poria, Platycodon, and Licorice. Sweating relieves the surface, dispersing wind and removing dampness. It is used for colds, headaches and body aches, aversion to cold without sweating, nasal congestion and clear discharge, and coughs with white phlegm.
Jingfang Granules, the formula is derived from the ancient prescription Jingfangbaidu Powder for treating colds in four seasons. Schizonepeta, Fangfeng, Qianghuo, and Duhuo can dispel cold and dispel wind, remove dampness and relieve pain, and remove external evils; Bupleurum, Citrus aurantium, Platycodon, and Chuanxiong can regulate the flow of Qi, remove stagnation in the middle, and promote blood circulation; Poria can reduce phlegm and dampness; Licorice can nourish the spleen, replenish Qi, and harmonize the medicinal properties. The purpose of the whole prescription is to relieve the symptoms, remove evils, dredge and regulate qi, blood and body fluids, so that external evils can be eliminated and healthy qi can be restored.
Modern pharmacology research shows that Jingfang Granules can resist the increase in body temperature of rabbits caused by skim milk, and has an obvious antipyretic effect; it can significantly reduce the increase in pneumonia index caused by influenza viruses, and has an obvious antiviral effect; acute toxicity test and long-term toxicity test, no obvious toxic side effects.
Clinically, Jingfang Granules are widely used in the prevention and treatment of acute/ viral upper respiratory tract infections, H1N1 influenza, acute bronchitis, and other diseases. It can significantly improve patients' symptoms such as fever, headache, sore throat, sputum and other symptoms. The results of multiple clinical trials of new coronavirus pneumonia have shown that compared with patients with new coronavirus infection who receive Western medicine treatment, TCM syndrome differentiation treatment including Jingfang Granules (Jingfang Baidu Powder) combined with Western medicine treatment can significantly improve the patient's symptoms and shorten the time for viral nucleic acid to turn negative.
Currently, Jingfang Baidu Powder and Jingfang Granules have been included in the new coronavirus prevention and treatment plans in Shandong, Yunnan, Xinjiang and other provinces. Other studies have shown that Jingfang Baidu Powder has a good anti-inflammatory effect on inflammatory mouse models. Its prescription medicine Qianhu and the active ingredients glycyrrhizic acid and naringin all have antitussive effects.
