A study published by Li Jing et al. from Fuwai Hospital and Xie Hongwei et al. from Hengyang Medical College of the University of South China suggested that elevated concentrations of sulfur dioxide in the atmosphere are related to an increased risk of hospitalization for heart f

2025/10/0820:47:35 regimen 1718

Fuwai Hospital Li Jing et al. and Nanhua University Hengyang Medical College Xie Hongwei et al. published a study suggesting that the elevated concentration of sulfur dioxide in the atmosphere is related to the increased risk of heart failure hospitalization. Elderly patients in the warm season (April to October) and in southern areas are particularly susceptible.

The main source of sulfur dioxide is the combustion of sulfur-containing minerals (such as sulfur-containing coal, etc.).

This study is based on the China-PEACE study, which collected data on nearly 120,000 heart failure hospitalizations in 62 cities in my country in 2015, and obtained daily sulfur dioxide concentration and meteorological monitoring data to analyze the relationship between sulfur dioxide concentration and the risk of heart failure hospitalization.

results showed that for every 10 μg/m³ increase in sulfur dioxide concentration, the risk of heart failure hospitalization on the day of exposure and 1 day after exposure increased by 1.2% and 1.1%, respectively.

A study published by Li Jing et al. from Fuwai Hospital and Xie Hongwei et al. from Hengyang Medical College of the University of South China suggested that elevated concentrations of sulfur dioxide in the atmosphere are related to an increased risk of hospitalization for heart f - DayDayNews

Subgroup analysis showed that in people aged ≥65 years, elevated sulfur dioxide exposure concentrations increased the risk of heart failure hospitalization on the day of exposure and 1 day after exposure, but there was no significant association between the two in people aged 18 to 64 years.

In addition, elevated sulfur dioxide concentration was associated with the risk of hospitalization for heart failure on the day of exposure and one day after exposure among residents in the southern region, but there was no significant association between the two in the northern region .

In the warm season (April to October), elevated sulfur dioxide concentration has a significant impact on the risk of heart failure hospitalization on the day of exposure, but has no such effect in the cold season (November to March of the following year).

The author pointed out that the mechanism of the impact of elevated sulfur dioxide concentration on heart failure is still unclear. It may be that sulfur dioxide causes an increase in cardiac load and oxygen consumption , causing the body to produce inflammatory responses and oxidative stress responses, leading to vascular endothelial dysfunction, atherosclerosis and cardiac remodeling.

Subgroup analysis of different ages found that people aged ≥65 years are more sensitive to changes in sulfur dioxide concentration, suggesting that the elderly are the group that needs to be focused on.

Source

Fu Ziwei, Shi Yu, Li Yichong, et al. Effects of short-term exposure to sulfur dioxide on the risk of hospitalization in heart failure patients. Chinese Journal of Circulation , 2022, 37: 1042-1047. DOI: 10.3969/j.issn.1000-3614.2022.10.012

Reprint: Please mark "China Circulation Magazine"

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