Recently, Xiaojiu received a private message from a netizen. She asked:
"I am only 35 years old this year, but my face has started to grow chloasma! Xiaojiu, I heard that vitamin E can remove freckles , I would like to ask if it is useful to go to the pharmacy to buy vitamin E tablets? Will eating too much vitamin E have any effect on the body? "
In fact, fans often ask Xiaojiu about taking vitamin E related questions, and many people I think vitamin E can resist aging, so what are the effects of vitamin E? What should I pay attention to when taking vitamin E? This time Xiaojiu will tell you in detail.
1. Research found that supplementing vitamin E may enhance the effect of immunotherapy
In April this year, a study published in the top oncology journal Cancer Discovery found that vitamin E can enhance the immunotherapy response of cancer patients .
researchers combined clinically recorded regression analysis with in-depth laboratory research and found that vitamin E can directly target DC intrinsic checkpoint SHP1, thereby revitalizing DC antigen presentation and initiating T cells for anti-tumor immune response.
That is to say, vitamin E can improve the immune checkpoint treatment effect in cancer patients.
In addition, there is also a saying that vitamin E helps prevent cancer. Is it true or false?
A study in the Journal of the National Cancer Institute found that vitamin E supplementation may reduce the risk of cancer, but is limited to specific alleles carrying catechol-O-methyltransferase (COMT) gene individual.
researchers found that after taking vitamin E, the total cancer incidence in met/met individuals was significantly reduced, and the total cancer incidence in val/val individuals, including lung cancer, breast cancer, uterine cancer and lymphoma Leukemia, etc., significantly increased, but had no effect in val-met individuals.
In addition, another study published in the Journal of the American Medical Association pointed out that taking excessive vitamin E (400 international units per day) will increase the chance of men suffering from prostate cancer .
Therefore, vitamin E cannot be supplemented casually or excessively, and random supplementation may increase the risk of disease.
It should be noted that the following three types of people are not suitable for vitamin E supplementation:
cancer radiotherapy patients : Because supplementation of vitamin E may lead to weakening of the efficacy of radiotherapy.
Breast cancer patients : Because vitamin E is mostly found in some cooking oils, eggs, meat and nuts, excessive fat intake will increase the risk of breast cancer recurrence.
General healthy people : It is not recommended to supplement vitamin E in order to prevent diseases.
2. Vitamin E is taken orally to prevent aging, can it be used externally to lighten the spots?
Vitamin E has always been known as a beauty ingredient. Many people believe that oral vitamin E supplements can delay aging, and applying vitamin E to the face can lighten spots and improve skin quality. Can vitamin E really resist aging and fade spots?
In daily life, air pollution, water pollution, ultraviolet ray exposure and excessive pressure may accelerate aging and lead to illness, and people's skin will also become worse, such as wrinkles, sagging faces, and loose skin.
, and vitamin E can inhibit and eliminate free radicals , protecting cell tissue from the damage of free radicals . Therefore, vitamin E has antioxidant and anti-aging effects.
However, people who are not lacking in vitamin E do not need additional supplements. Generally, you can get enough vitamin E as long as you eat a healthy diet.
As for the effect of "external use can lighten spots", vitamin E does not have it.
Topical vitamin E can effectively prevent skin photoaging caused by ultraviolet rays, and can also reduce acute inflammatory reactions such as erythema and edema caused by sun exposure.
However, the effect of vitamin E on freckle removal and whitening is not accurate at present. plus vitamin E has extremely low stability, and it is easy to oxidize , which often need to be used with other reducing substances such as vitamin C.
It should be noted that Do not use oral vitamin E to apply to the face in daily life, because in order to facilitate the use and facilitate the absorption of the gastrointestinal tract, more than 90% of the ingredients are auxiliary materials, these oily substances in the skin It is inabsorbable.
Applying vitamin E externally to oily skin and acne skin will actually make the skin oily, and clog pores, thereby inducing more acne.
If you can take vitamin E correctly, you may gain the following benefits:
, anti-aging
Vitamin E can protect the fatty acids on the cell membrane from oxidation, thereby keeping the cell membrane active and metabolism normal, and slowing down the cell aging rate , human aging will naturally be delayed.
, enhance immunity
Vitamin E can regulate and enhance immune function. For example, patients with rheumatoid arthritis regularly supplement vitamin E, which can effectively improve the discomfort symptoms of joint stiffness and pain in .
. It helps hormone secretion
Before going to bed at night, taking appropriate amounts of vitamin E can promote the secretion of sex hormones in the body. For men, it can increase the number of sperm and its survival rate, and for women, it can increase the concentration of estrogen, and thus increase the concentration of estrogen, thereby increasing the concentration of estrogen, thereby increasing the concentration of Ability to give birth.
3. Don’t abuse vitamin E, it’s a big harm
Although vitamin E has many benefits, if it is not used reasonably, it may also bring many harm to the body.
If you take 400-800 mg/day of vitamin E a day for a long time, it may cause symptoms such as headache, dizziness, blurred vision, nausea, abdominal pain, diarrhea and breast enlargement;
If you take 400 mg/day of vitamin E a day for a long time, it will be correct. Patients who lack vitamin K may cause bleeding tendencies, and may also change endocrine metabolism and immune mechanisms, and may also increase the risk of diseases such as thrombophlebitis, thromboembolic and heart failure .
may really need additional vitamin E supplements, are those who have severe partial eating habits, eat disorders, or suffer from certain vitamin deficiency diseases.
In addition to oral supplements, vitamin E can also be supplemented through diet.
Vitamin E is found in vegetable oils, nuts, seeds, fruits and vegetables, such as wheat germ oil, soybean oil, sesame oil , sunflower seeds, almonds, peanuts, beet , kale , spinach, pumpkin, lamb liver , bean curd, mulberry, walnut, cereal products, etc.
Vitamin E is not only an essential vitamin for the human body, but also the most important antioxidant. It is important for vision, reproduction, blood, brain and skin health.
When there is a lack or excessive vitamin E in the body, it will have a series of adverse effects on the body. However, before supplementing vitamin E, you should consult a professional doctor and take it at the dosage under the guidance of the doctor.
Reference materials:
[1]Yuan X, Duan Y, Xiao Y, Sun K, Qi Y, Zhang Y et al. Vitamin E Enhances Cancer Immunotherapy by Reinvigorating Dendritic Cells via Targeting Checkpoint SHP1. Cancer Discovery. 2022;12(7 ): 1742-1759.
[2] Hall K, Buring J, Mukamal K, Vinayaga Moorthy M, Wayne P, Kaptchuk T et al. COMT and Alpha-Tocopherol Effects in Cancer Prevention: Gene-Supplement Interactions in Two Randomized Clinical Trials. JNCI: Journal of the National Cancer Institute. 2019;111(7): 684-694.
[3]《 Vitamins cannot be supplemented with vitamin E and supplement excessive amounts or cancer. Life Times. 2019-08-11
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