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According to the UK Sky News (February 5, 2020), Professor Robin Shattock, a scientist at Imperial University of Technology in London, has made a major breakthrough in the development of the novel coronavirus vaccine.
Professor Shatok told Sky news that his team has made "significant breakthroughs" and can shorten the normal development time of a vaccine at one stage from the usual two or three years to just 14 days. "The research team will start testing vaccines on animals as early as next week, and human trials will be conducted as early as this summer," said Shattock. "
The scientist leading the UK's research into a coronavirus vaccine says his team have made a significant breakthrough by reducing a part of the normal development time from "two to three years to just 14 days".
Professor Robin Shattock said he is now at the stage to start testing the vaccine on animals as early as next week with human studies in the summer if enough foundation is secured.
Imperial University of Technology's Mucosal Infection and Immigration Department Professor Robin Shattock
Shattock is accepting Sky "Using traditional methods usually takes at least 2 to 3 years to get the vaccine in clinical trials, but we have found a candidate vaccine protocol from this sequence in the lab within 14 days."
"Earlier next week, we will try this vaccine in animal models. We have shortened the development time for this part, and the next phase will move from early animal trials to the first human study.
"We think that if there is enough funding, we can do the trials in humans in a few months. ”
He told Sky News:
"Conventional approaches usually take at least two to three years before you even get to the clinic. And we've gone from that sequence to generating a candidate in the laboratory in 14 days.
"And we will have it in animal models by the beginning of next week. We've short-tracked that part. The next phase will be to move that from early animal testing into the first human studies.
"And we think with adequate foundation we could do that in a period of a few months."
In response to the spread of the epidemic, Professor Shatok added: "The novel coronavirus has become an epidemic, and it is not too late to stop it from spreading around the world. We still don’t know much about the pandemic itself, so it may weaken like the flu, during the summer months. "
. Regarding the question that the vaccine development time may be too long, Shatok said:
"We may see a second wave of epidemics around the world. If it occurs, this vaccine will be very important and there will be a way to deal with it. "
For the major breakthrough claimed by British scientists, Professor of Infectious Diseases, Department of Microbiology, Li Ka-shing School of Medicine, University of Hong Kong, Yuan Guoyong commented:
"Vaccine will take months to test in animals, while clinical trials in humans will take at least one year. This breakthrough in the UK is of great significance because it greatly shortens development time. ”Handl4
After the news came out, the stock market quickly responded to
According to the latest report from Reuters (February 5), the positive news of the coronavirus vaccine research in the UK has driven market sentiment.
was boosted by this news, and global stock markets rose rapidly after the opening, especially in stock markets in European countries.
As of press time, the UK's FTSE 100 index rose 0.73% to 7493.93 points; the French CAC40 index rose 0.86% to 5986.10 points; the German DAX index rose 1.16% to 13435.47 points.
Stock Europe 600 Index reversed its initial decline, rising by as much as 0.8% intraday. U.S. stock index futures also turned above the flat market, up 0.5%.
Reuters quoted several traders in London as saying that the stock market has risen sharply due to reports on the breakthrough of vaccines, and traders believe that these news has caused market volatility.
According to Reuters analysis, the positive for the stock market is more about the emotional level, and the "breakthrough progress" itself focuses on the speed at which vaccine research enters animal experiments.
As Professor Shatok of Imperial Engineering said, it will take several months to implement clinical experiments. It will not help much for the current epidemic. It is highly likely that it can only be prepared for future epidemic prevention.
The British government allocated another £20 million, with a total of £40 million in funding to support the development of the new crown vaccine.
This Monday (February 3) the British government promised to provide £20 million to CEPI (Global Epidemic Prevention Innovation Alliance) , which has a research institute in London, to support its research on the novel coronavirus vaccine.
Today (February 5), British Health Secretary Matt Hancock announced an allocation of another £20 million, funding a total of £140 million (about 360 million yuan) to support the development of new pneumonia vaccines.
With the support of the British government, there are also new progress in British women's science
In addition, according to subsequent in-depth reports from the BBC, the latest funding from the UK will be mainly used to fund the research project of CEPI member-British female scientist Kate Broderick (Kate Broderick) .
The UK's money will help fund the efforts of Dr Kate Broderick, a 42-year-old Scot, who is working to create a coronavirus vaccine.
It is reported that after receiving $9 million funded by Bill Gates , a team led by British scientist Kate had already started developing vaccines on the day of the outbreak (that is, December 31, 2019).
. After , the Chinese Center for Disease Control and Prevention recently released the strain information of the novel coronavirus (2019-nCoV), Dr. Kate led the team to quickly design the vaccine, currently named "INO-4800", and is racing against time to conduct preclinical testing.
During this vaccine development, her team used a new type of DNA technology to speed up development and test it on animals, and plans to enter the human clinical trial stage of the "INO-4800" vaccine by early summer this year.
If the initial human clinical trial is successful, larger-scale trials and improvements will be carried out. The whole process takes about 6 months and then mass production.
Kate said in an interview with the British Times: "The virus has no borders, and such a long incubation period will lead to the accelerated spread of the new coronavirus worldwide."
Kate, who is stepping up testing, said: "I hope this vaccine can be conducted faster in human clinical trials to confirm safety to save those in pain. ”
British investors wrote at the end
Although scientists are accelerating the work, many processes are still inevitable. Strict clinical trials and various manufacturing challenges mean that it is likely that the vaccine will take at least nearly a year to be put into use worldwide.
virus has no borders, which not only means that the epidemic spreads so quickly, but also shows that all human beings should join this battle.
This week, the British government has allocated two consecutive funds to fund 140 million pounds . In addition, the efforts of CEPI scientists and professors of Imperial College, I sincerely hope that we can win this battle against the epidemic as soon as possible.
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