Jimu News Reporter Song Qingying
On October 5th local time, the 2022 Nobel Prize in Chemistry , known as the "Comprehensive Science Award" was released. American scientists Caroline Bertozi, Carl Barry Shapleis and Danish scientist Morten Meldar shared it. Jimu News found that Bertozi is a "cross-border academic master", and Shapleis won the Nobel Prize for , but he also made great sacrifices for science.
After 21 years, Shapley, two-time Nobel Prize winner, was born on April 28, 1941 in Philadelphia, Pennsylvania, USA. In 1968, he received his Ph.D. from Stanford University.
Shapris won the Nobel Prize in 2001 (Picture source: Nobel Prize official website)
Shapris won the Nobel Prize in Chemistry in 2001. This makes him the second person in history to win two Nobel Prize in Chemistry after Frederick Sanger .
Shapris is well known for its research on asymmetric synthesis, and named three chemical reactions after Shapris: catalytic asymmetric epoxidation reaction, dihydroxylation reaction and ammonia hydroxylation reaction.
In 2001, Shapley won the Nobel Prize in Chemistry of the year with her outstanding contribution in chiral catalytic oxidation reactions. Knowles shared half of the Nobel Prize in Chemistry with Nobel Prize, and Shapleis won his other half.
In recent years, he has introduced new concepts of click chemistry, becoming one of the most useful and attractive synthesis concepts in many fields of drug development and molecular biology . Based on his outstanding contribution to click chemistry, an analysis company predicted that he would win the Nobel Prize in Chemistry for the second time, and this prediction really came true in 2022.
Discovered from blindness in the experiment, and wrote an article to warn researchers
However, Shaplers, a chemistry master, unfortunately lost one eye.
In 1970, Shapley won an assistant professor position in MIT , this misfortune occurred in an experiment.
At the early morning of the day, when he was about to go home from the lab, he wanted to go to the compartment to see what his colleagues were doing. A first-year graduate student was flame sealing the MRI tube. Shapleis picked up the MRI tube and observed it at the lamp. Unexpectedly, the test tube was foggy. After Shapleis wiped the test tube, he noticed that the solvent content was very high. Suddenly, the solvent level dropped by a few inches.
"Although I immediately realized that the concentrated oxygen had been sealed in the MRI tube, I really couldn't move it before the explosion."
nuclear magnet exploded, and glass fragments shambled the cornea of one of Shaplers' eyes, penetrated the retina, and caused the eyeball to be partially pierced.
His eyes were completely unable to move for the first two weeks, and the pain was abnormal. His injured eyes lost functional vision, but fortunately his other eye still maintained full vision.
Short essay written by Shapley
Shapley later wrote this experience into a short essay. Now this article called "The Warning Stories of the Past" is still on the official website of the MIT, reminding researchers to wear safety glasses at all times.
Female chemistry genius is also rock "Day Queen"
Nobel Prize official website commented on the chemistry prize: "Sometimes the simple answer is the best. Shaplers and Meldar brought chemistry into the era of functionalism and laid the foundation for click chemistry. Bertozi brought click chemistry to a new dimension and began to use it to draw cell maps. Her bioorthogonal reactions now help more targeted cancer treatments, as well as many other applications."
Bertozi (Photo source: Stanford University official website)
Caroline Bertozi is the only woman among the three winners. In addition to being a chemist, she is also a rock enthusiast.
Bertozzi won the MacArthur Genius Award at the age of 33. In 2010, she became the first woman to win the Lemaelson-MIT Award.
According to the magazine " World Science ", Bertozzi was born in October 1966. Her father was a professor of physics at MIT, but after she entered Harvard University, she once wanted to major in music. "My parents didn't want me to choose this. A relative of mine was engaged in a music career, but ended up paying the rent by working in a bank. I didn't dare to disobey them."
So, Bertozzi chose a pre-medical course including mathematics and science courses, and decided to major in biology at the end of his freshman year.
But her music career did not give up halfway. While many classmates were working as waiters in restaurants to pay for college, she played electronic piano in a heavy metal rock band and sang back. It was the 1980s, and her band often played her own metal rock or pop songs at events like college parties.
(Source: Jimu News)
For more exciting information, please download the "Jimu News" client in the application market. Please do not reprint without authorization. You are welcome to provide news clues and you will be paid once adopted. 24-hour information reporting hotline 027-86777777.
