The team of Li Wenxiong, a distinguished researcher at the Biodiversity Research Center of Academia Sinica, discovered that six mutation points in the human ACE2 receptor have particularly poor binding ability when encountering the S protein of the new coronavirus. That is, peopl

Li Wenxiong’s team, a distinguished researcher at the Biodiversity Research Center of Academia Sinica, discovered that six mutation points in the human ACE2 receptor have particularly poor binding ability when encountering the S protein of the new coronavirus. That is, people with these gene mutations , it is not easy to contract COVID-19, and the other three mutation points make the human body particularly susceptible to infection. The research results related to

have been accepted by international journals and have not yet been published. According to the United Daily News, Li Wenxiong, an academician of the Academia Sinica, mentioned the above message when he was invited to give a speech at Tainan No. 1 Middle School. The team pointed out that ACE2 has functions such as stabilizing blood pressure and endocrine function in the human body. The team used luciferase labeling to find out 9 mutation points on ACE2, which will affect the binding with the virus S protein. Three of them will cause the human body to The affinity between the cells and the virus increases by 1.4-1.8 times, which means they are susceptible to virus infection. The other 6 have the affinity dropped to only half or even close to zero, making it difficult or impossible to be infected. Can humans be completely immune to infection by modifying genes? Li Wenxiong said that based on the current situation, there may not be many people with these mutated genes. At the same time, these mutations have nothing to do with the height of human blood pressure, or the recently mentioned vaccine side effects such as blood clots. He said that the latest vaccines developed, including the Pfizer and Moderna vaccines, are all mRNA vaccines, which are relatively easy to manufacture and can quickly respond to virus mutations to create new vaccines. Even if the vaccine is old, it can still have an effect on the human body. If infected, the disease will be milder and less contagious. As for the side effects of vaccines that everyone is currently concerned about, Li Wenxiong believes that "side effects only mean that the vaccine is effective" and there is no need to worry too much.