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In November 2022, Siemens Medical issued an announcement that will invest millions of pounds to establish a medical center of excellence in Llanberis to manufacture IMMULITE blood analysis technology, to consolidate its global business.
It is reported that the investment in will transform the base into a research and development center for laboratory diagnosis, so as to develop products with higher diagnostic accuracy for optimizing patient care. is expected to be completed by the end of 2024, and this move will guarantee 400 jobs and create nearly 100 new jobs.
1
Set up a R&D center to consolidate global business
Siemens Healthineers Llanberis is a global brand in the diagnostic industry. It was founded in 1992 and covers an area of 36 acres. Since its establishment, Siemens Healthcare has been developing its business in Llanberis;
- 993, Siemens Healthineers Llanberishml1 launched the IMMULITE system ;
- 998, launched the IMMULITE 2000 system and won the Queen's Export Award;
- 002, IMMULITE 1000 system launched . In the same year, Prince Charles visited to celebrate its tenth anniversary;
- 010, the Llanberis factory became the IMMULITE transferred from Los Angeles The only manufacturer of reagent production, production increased by 130% ;
- 015, established a partnership with University of Wales to share the development vision of economic development in North Wales;
- 017, Siemens transferred IMMULITE research and development support activities to Llanberish, including early development;
At present, the Llanberis factory has produced more than 950 IMMULITE products for 100 disease states and 570 allergy tests, are shipped to distribution centers in Europe and the United States, and then distributed to laboratories and clinics in more than 50 countries around the world.
At this celebration, Minister of Economic Affairs Vaughan Gething said: "I am pleased to announce this significant investment with Siemens Healthcare - the establishment of a new R&D Centre of Excellence in Llanberis. Thanks to the Welsh Government's support, this will create hundreds of high-quality jobs for Gwenes."
" Siemens Healthineers Llanberis is a strategic employer across the North, and this investment is a huge vote of confidence in the Wales economy. The economic contract we signed with Siemens Healthcare Group ensures the future of the existing factory, establishes a new R&D organization that promises fair work and a healthy and inclusive working environment over the next few decades. ”
Fraser, Vice President and Managing Director, Siemens Healthcare Professor Logue added: “ Laboratories and clinics in more than 50 countries around the world rely on the IMMULITE reagents we produce in Llanberis. The investment from the Welsh government is a testament to the critical work done by our more than 400 colleagues and will enable us to advance our planned investment in the website.
“We will create nearly 100 highly skilled jobs to realize the shared ambition to transform Siemens Medical Llanberis into a global center of excellence in laboratory diagnostic manufacturing and R&D. ”
2
Strong layout of IVD, and three mergers and acquisitions in two years
Siemens Healthineers (Siemens Medical Group) is a health care company established by Siemens Group in 1896. As one of the earliest multinational medical device companies to take root in Pudong , in the past 30 years, Siemens Medical has gradually established three R&D and production bases in Shanghai, Shenzhen, and Wuxi . With the establishment of Siemens Medical Shanghai Innovation Center in Pudong last year, the addition of two production bases in Beijing and Hangzhou has formed a strong local layout that emphasizes both production and R&D. has also allowed Siemens Medical to further deepen its local area, consolidate its identity as a "Chinese enterprise", and grow together with the Chinese market.
At the same time, as the leading company in the global in vitro diagnostic business field, it has maintained a high share in the Chinese market. Global IVD market share shows that Siemens accounts for 7.8%, ranking fourth after Roche, Abbott , and Danaher . In 2022, Siemens Healthcare revenue was US$20.517 billion.
The rapid development of Siemens Medical's in vitro diagnostic product line began in 2006 and 2007. In the past two years, had a sensational three mergers and acquisitions in the entire IVD field. , that is, in July 2006, it acquired Depp Diagnostics (DPC) for 1.5 billion euros, in January 2007, it acquired Bayer Diagnostics for 4.2 billion euros, and in November 2007, it acquired Depp Diagnostics for 7 billion U.S. dollars, making it quickly form the most complete product line. Currently, Siemens has the most complete IVD product line, including immuno, biochemical, molecular, hematocytogenesis, POCT, etc. is the manufacturer with the most complete layout in the IVD field.
blood analyzer is called hemocytometer in clinical practice. It is a computerized and highly specialized machine. can calculate the number of different types of reds and the levels of white blood cells, platelets, , hemoglobin and hematocrit in blood samples.
They include programmable automatic alerting systems for indicating results beyond the reference range. Blood analyzers involve disease detection, monitoring, prognosis and follow-up screening. is widely used in various blood-related diseases, such as , such as hemophilia , blood cancer and thrombosis. Other diseases include leukemia , anemia , blood transfusion, malignant lymphoma , and other diseases diagnosed using hematology.
blood cell analyzer According to the ability to classify leukocytes, it can be divided into a leukocyte-free functional blood cell analyzer, a two-swarm blood cell analyzer, a three-swarm blood cell analyzer and a five-swarm blood cell analyzer. Currently, the three-group and five-category blood cell analyzers are mainly used in medical institutions at all levels.
Siemens immulite 2000
immulite2000 fully automatic immunoassay device has the advantages of good repeatability and high sensitivity of , and the detection speed of sample is 200/h. Since its use, the instrument has stable performance, convenient operation and high compliance with the clinical evaluation software evaluation results.
As an outstanding representative of fully automatic chemiluminescence immunoassays, has a unique enzyme amplification chemiluminescence technology, patented elution technology, and high sensitivity and specificity. is used more and more widely in various laboratories and has been well used in China and even the whole world.
Siemens immulite 1000
Immulite 1000 Chemiluminescence immunoassay device, after years of practical testing, the system equipment has excellent hardware quality and excellent detection performance. The computer, keyboard, monitor, built-in probe flushing device and water tank are integrated and packaged in the system to reduce the device volume . is a better choice for small and medium-sized experiments.
It has 's extensive menu functions , which can truly realize a single instrument, a single patient, and multiple tests, and complete it at the same time, saving expenses and improving laboratory efficiency. In addition, can perform single-item detection or multiple-item detection at any time. The sample turnover time is short and the samples can be processed continuously. Emergency samples can be added at any time as needed, greatly shortening the processing time. At the same time, can monitor the test reagent status, dilution status, and identify positive samples in real time, and support remote diagnosis.
Siemens immulite 2000XPi
New Immulite 2000 XPi fully automatic chemiluminescence immunoassay, simple and easy to use, high reliability, has a comprehensive immunoassay menu, suitable for large and medium-sized laboratories. Special detection and allergen detection can be added to routine detection to improve processing capacity and work efficiency.
In addition, Immulite 2000 XPi can automatically run fully automatic routine maintenance programs and quality control programs, automatic sampler, no shutdown is required, keeps the instrument in "ready" state. Not only that, the advanced technology adopted by the system not only improves detection and processing capabilities, but also shortens the downtime of . The system can also be set up. Once all the samples on the sample holder have been removed or the result is obtained, the sample holder will pop up automatically immediately, and the sample tube is topped with a sample cup. is suitable for small sample detection, simplifying the operation process without repeated labeling.
3
Hypercellular detection mechanism inventory
Early blood cell detection equipment can be traced back to 1590, the most primitive microscope designed and manufactured by the Dutchman Middleborg and Jansen. Later, this microscope developed and improved . In 1658, Italian Marpiki observed red blood cells for the first time under a microscope. thus guided people to gradually realize that the number of cells in the blood is related to the occurrence and development of diseases, and thus prompted scientists to begin to study cell counting methods.
After more than 100 years of application, evolution and development, by 1953, Wallace H. Kurt of the United States Beckman Coulter Company and his brother Joseph R. Kurt Jr., after nearly ten years of hard work, proposed the famous Kurt principle, , the electrical impedance principle, and obtained a US patent that year, and launched the first hemocytometer the following year. Therefore, the Kurt principle has become the most classic principle in hemocytometer and analysis.
Beckman Coulter came from Beckman in the United States in 1997 and renamed Beckman Coulter, which later Danaher Group acquired Beckman Coulter, which is now Danaher Beckman.
974, the first leukocyte analyzer with preliminary leukocyte classification function, was released. This product can initially divide white blood cells into five categories: lymphocytes , monocytes , eosinophils, basophils and neutrophils.
1980 This technology has further matured, and launched a product H6000 blood cell analyzer that can achieve the five-level classification of blood cells. Since then, various companies have been constantly innovating in the five-categorization technology of leukocytes. Representative products include Sysmex's multi-channel impedance , radio frequency and cellular chemistry joint detection technology, Abbott's multi-angle polarized light (MAP) technology, ABX's cellular chemistry lipid total staining technology combined with double sheath flow (DHSS) technology, etc.
my country began to develop blood analyzers as early as the 1960s. In Shanghai, China's first generation of hemocytometer was produced. From to the 1970s, the development, production and application of domestic blood analyzers were developed rapidly. In the 1970s, Beijing also produced blood cell counting instruments that simply imitated foreign brands, such as the early production of blood cell counting instruments from Shanghai XF503, the PC-703 produced by Dandong Liaoning Radio Factory No. 7, Beijing COULTERZF, Nanjing XF-1, Jinan DXJ-l, and other manufacturers.
These only instruments can count red blood cells and white blood cells. With the reform and opening up of , some domestic manufacturers cooperated with foreign countries to produce the second generation of blood cell analyzer . Among them, the most famous and widely used ones are ERMAPC-603 and PC-604. The instrument is easy to operate and has an open diluent. The main parameters of the instrument include three parameters: red blood cells, white blood cells and hemoglobin. PC-604 has added a special calculator above the host, so MCV, MCH, MCHC, HCT can be obtained and the results can be printed. In addition, there is a PC-601 platelet count dedicated to platelet counting .
From then on, due to various leukocyte-containing two-part and three-part groups abroad, a large number of hemocytometers with automatic dilution have entered the Chinese market, greatly impacting the status of domestic hemocytometers. At the same time, due to the lack of technology and funds, domestically produced hemocytometers have not been further developed. Among the domestic blood analyzer manufacturers, the largest market share is Mindray .
Minery Medical
Minery Company is China's leading high-tech medical equipment research and development manufacturer, and is also one of the innovative leaders in medical diagnostic equipment in the world. Since its establishment in 1991, Mindray has been committed to the research and development and manufacturing of clinical medical devices, and Mindray's sales have expanded to more than 140 countries and regions around the world.
In the field of in vitro diagnosis, Mindray has created many firsts. The first fully automatic blood cell analyzer in China was produced by Mindray. Mindray's blood cell products are very detailed, and there are many models of products that are very close to the price and parameter gaps.
There are 6 models in three categories: BC-20S, BC-30S, BC-2300, BC-2800, BC-3000plus, BC-3600.
categories 8 models: BC-5000, BC-5150, BC-5310, BC5390, BC5390CRP, BC-5800, BC-6800, BC-6900.
Batte Bio
Company was founded on March 8, 1993. After more than 20 years of development, the company has become a high-tech enterprise integrating science, industry and trade. It is one of the largest R&D and production bases in China. The company is located in , Changdong Industrial Zone, Nanchang, covering an area of 130 mu and a building design area of about 22,800 square meters. Now there are more than 200 employees, and technicians account for 40%. The business scope covers the whole country and is exported to dozens of countries including Germany, Iran, S.A., Iran, Vietnam and India.
independently developed and produced HL series blood analyzers and reagents. It has complete independent intellectual property rights and has won many national invention patents and Jiangxi Province, Nanchang City Science and Technology Progress Award. At the same time, the company continues to innovate and pioneered a new business model for the overall solution of intelligent clinical laboratory, truly realizing a one-stop solution for clinical laboratories from design to engineering, laboratory benches, instruments and equipment, LIS system, training, reagents and consumables, maintenance and certification.
Eulite Medical
Eulite Group is a first-class medical diagnostic product manufacturer, supplier and service provider in China, and national high-tech enterprise . After more than 30 years of development, it now has blood cell analysis system, urine analysis system, biochemical analysis system, real-time inspection (POCT) diagnostic products, etc.
Ulit has the genes of state-owned enterprises. In addition to the strong product urine analyzer , blood analyzer products have a small share in the high-end market, and their products are mainly used in secondary and primary hospitals .
classification: BH-5380CRP; URIT-5510 five-category fully automatic blood cell analyzer, classic MAPSS classification technology for cell morphology analysis, speed measurement up to 110T/H, suitable for large-scale specimen detection such as physical examination; URIT-5380; URIT-5250; URIT-- 5180; URIT-5190
Tekang Technology
Jiangxi Tekang Technology Co., Ltd. was established in 1992. It is a national high-tech enterprise specializing in the research, development, production and sales of medical equipment and in vitro diagnostic reagents . Tekang Technology Company successfully developed blood analyzers and supporting reagents with independent intellectual property rights, and quickly industrialized them. In 2007, it won one second prize in National Science and Technology Progress Award; two first prizes in Jiangxi Provincial Science and Technology Progress Award; participated in the drafting and formulation of national industry standards for blood analyzer reagents; the company has established an engineering technology research center and a national postdoctoral workstation with the state.
Category: TEK8550; TEK8510; TEK8520
Category: TEK5000P
Diri Medical
Changchun Dirui Medical Technology Co., Ltd. was established in 1992. It mainly engages in urine analysis, urine formation analysis, blood cell analysis and other series of products and related supporting test strip reagents. Its predecessor was Changchun Dirui Industrial Co., Ltd. . In 2010, it was changed to Co., Ltd. . Dirui Company has always been committed to the research, development, production and sales of high-quality medical inspection products. On September 10, 2014, Dirui Company was listed on the Shenzhen Stock Exchange GEM, with stock code :300396.
products include: BF-7200Plus fully automatic modular blood fluid analysis system; BF-6900CRP fully automatic five-class blood cell analyzer; BF-6900 fully automatic five-class blood cell analyzer BCC-3900 fully automatic blood cell analyzer; BCC-3600 fully automatic blood cell analyzer
Dimai Bio
Shenzhen Dimai Biotechnology Co., Ltd. is a high-tech enterprise specializing in the research, development, production, sales and services of medical devices. , Dimai Bio, established in 2013, was launched in the market in just one year after its establishment. In just five years since , Dimai Bio's R&D team has reached 130 people and has successfully launched 12 blood cell products.
Dimai Bio attaches great importance to R&D investment. 's annual R&D investment has accounted for more than 10% of its revenue. Among the products it develops, some of is an innovative product in the global blood analyzer field. At present, Dimai's products have achieved large-scale coverage in China, and have undertaken an average daily sample testing volume of more than 1,000 in many large medical institutions. Thousands of medical institutions across the country are using Dimai's products, and the company's products are also successfully sold to more than 90 countries around the world.
Category:
DH51;DH55;DH71;DF50CRP; DF56CRP; DF71CRP; DH75CRP, etc.
Category: DH36; DH36X; DH31; DH26
Jinrui Biologics
Shenzhen Jinrui Electronics Co., Ltd. was founded in August 2004. It is mainly engaged in the research, development, production, sales and services of clinical medical testing equipment and reagents. Currently, it has fully automatic blood cell analysis and supporting facilities, and a total of dozens of varieties of serialized products. March 2011 KT6280 blood cell analyzer was selected as a 2010 medical device evaluation selection product by China Medical Equipment Association .
Category:
KT8000;KT6500;KT6510;KT6600;KT6610
Category: KT6200;KT6300;KT6400
Ledu
Ledu is a professional provider of clinical testing equipment and supporting reagents, and is a national high-tech enterprise and a software enterprise in Shenzhen. Redu has always been committed to the research and development, design, manufacturing, sales and after-sales service of medical inspection equipment, and all products have completely independent intellectual property rights. is at an advanced level in the field of technology such as blood cell analysis, and has obtained several national, provincial and municipal key new product qualifications.
In January 2018, Leidu's impact on A shares was rejected, bringing certain tests to the company's operations and management. The reason for being rejected is that the CSRC believes that Redu adopts the sales model of "dealer sales as the main and direct sales as the auxiliary" will put the company at the risk of a sharp decline in sales revenue.
categories:
Hemaray 86; Hemaray 83; Hemaray 50CRP
categories: RT-7600; RT-7300; RT-7600Vet
