“Human life is limited. Everyone will experience birth, old age, sickness and death, but who can tell you why you can’t avoid birth, old age, sickness and death?”
“We all know that the unit of life is a cell. It starts from a small fertilized egg. "
" "Theoretically, human cells can divide up to 56 times during their survival, and by calculating the cell division cycle, the limit life span of human should be around 120 years old ( The brain is around 150), and this theory is called the Hayflick limit"
. So we hear a lot of anti-aging principles, some of which are based on cell activity, but if He told you that it can increase the number of cell divisions, which is basically fake, otherwise Nobel is not good?
"Cells will continue to divide and die over a long period of time, just like our proactive cry: 1 2 1. Repeated aging and apoptosis, and dividing new cells constantly replace old cells. This is the secret of our continuous growth. "Z1z
" It’s just a pity that this splitting process is not an endless refill of Coke. When the time comes, it will end."
" In 1965, Professor Hayflick of Stanford University discovered that human cells cannot replicate themselves more than 57 times. The cell will die after 56 copies. "
" The cell is like a printer. It prints a document every once in a while. When the print reaches the 56th time, the ink is used up, and no additional ink can be found. The way" this ink is called telomerase.
"At both ends of DNA, there is a kind of'telomere', which plays a vital role in cell division."
"It is responsible for keeping the chromosomes intact. Every time a cell divides, it will let the end The grains become shorter. When the telomeres are too short to protect the gene structure, the cells will inhibit growth, stop replicating, and enter aging."
"This is the Hayflick limit."
Since the birth of mankind, it has gone to heaven and earth. The technology of China has no way to solve this problem. This problem is also a stumbling block that hinders human eternal life (although eternal life is not a good thing).
Is there any way to solve this problem?
"The answer is yes!"
The answer is " HeLa cell line", the name HeLa is taken from the first two letters of the original patient Herita Lax’s name.
HeLa cells are a cell line of cervical cancer cells from a black American woman, Henrietta Lacks. A surgeon took a tissue sample from her tumor and cultured it in the laboratory, where it is still being cultured continuously.
is different from other normal human cells, this cell line will not age or die, and can divide indefinitely. Compared with other cancer cell lines, this cell line proliferates very rapidly. It has been 68 years since the birth of
to 2019. In the medical field, HeLa cells are widely used in tumor research, biological experiments or cell culture, and have become a very important tool in medical research.
"So, there is a common sense that everyone knows for later generations-cancer cell lines are'immortal', as long as there is a suitable culture environment, it can divide indefinitely."
"But we cannot try this way. To gain immortality, after all, once the cell division cycle in our body is disrupted and cannot age on time, it will turn into a malignant tumor, snatch nutrition from normal cells, and threaten our lives!"
"The average life span of human beings is constantly improving. With the blessing of science and technology, it has been increasing year by year. The average life expectancy of the top 28 in the world is above 80. The first is 83.7 (life expectancy) in Japan!"
Note: China [53] is 76.1 years old.
"But are we satisfied like this? No!"
"And even if human science advances, we pay special attention to maintenance and health, and we can live to 120 years old, then will we be satisfied? No, human desires are unlimited. We will also pursue 150 years old, 200 years old, so thisFar from reaching the level of immortality, what should we do? "The
Hayflick limit tells us that human cells can only divide 56 times, but if human cells can divide forever, can we live forever?
just find the opportunity to prevent the cell from dividing.
"So in 2002, this "opportunity" was finally found. 2002 Nobel: Sydney Brenner, Robert Horvitz and John Sulston used nematodes as biological research objects and found that cell death is There are genes to control, and there are fixed and regular program behaviors. "Z1z
" This discovery shocked the entire medical community, because it believed that cell death is a physiological and proactive ‘suicide’, like a programmed program in the dark! "Z1z
"In other words, we think that aging is a natural process, but in fact it may be a genetic defect! If we can repair this defect, we can hope to overcome aging and gain immortality! "Z1z
Of course, although there is a goal, but how many years can be achieved, or even whether it can be achieved, no one has a bottom line, scientific research is sometimes a bet on B, maybe tomorrow, maybe forever.
