Recently, the Air Force Medical University announced that the multi-organ and multi-tissue joint transplantation was successful.
In order to better solve the problem of multi-organ failure and the need for multi-organ multi-tissue transplantation, recently, led by Dou Kefeng, an academician of Chinese Academy of Sciences, in conjunction with 16 disciplines including cardiovascular surgery and urology, successfully carried out the world's first gene-edited pig-monkey joint transplantation at the same time, achieving a zero breakthrough in xenogeneic multi-organ multi-tissue transplantation. The
transplant surgery was carried out on October 16 and ended in 14 hours. The research team obtained three organs of liver, heart, and kidney of pigs, as well as three tissues of corneal, skin and bones, and four recipient monkeys performed liver and kidney combined transplantation, heart transplantation, , corneal and skin transplantation, and bone transplantation at the same time. As of press time, the four recipient monkeys, transplanted organs and tissues have survived well.
At present, the research on xenogeneic tissue organ transplantation with gene-edited pigs as donors has progressed rapidly internationally. Some preclinical trials have been carried out, but most of them are single tissues or organ transplants. This is the first time in the world that a variety of different tissues and organs are obtained from the same donor pig , and a joint transplantation of xenogeneic multi-organ multiple tissues at the same time. In order to explore and solve the problem of multi-organ failure and at the same time maximize the role of donor pigs, Xijing Hospital of the Air Force Medical University conducted such research.
After searching, this operation was the first international gene-edited pig-monkey multi-organ and multi-tissue joint transplantation, which further expanded and confirmed the possible scope of application of xenograft in the future, and provided scientific data and technical reserves for first aid for patients with donor shortage and organ failure.
Source: CCTV News
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