The point-of-care test (POCT) method is a point-of-care testing method. Compared with traditional testing methods, it eliminates the need for complicated processing procedures for specimens to be tested in the laboratory. It has the advantages of rapidity, simple use, wide applic

2024/05/0106:09:33 science 1959

The

point-of-care test (POCT) method is a point-of-care testing method. Compared with traditional testing methods, it eliminates the need for complex processing procedures when specimens are tested in the laboratory. It has the advantages of speed, simplicity of use, wide application range, and overall cost savings. .

Fuwai HospitalZhang Jian and others found that the detection of soluble growth-stimulating gene 2 protein (sST2) by POCT method is an independent predictor of all-cause death or heart transplant in patients with heart failure. Based on baseline NT-proBNP, The combined baseline sST2 may provide additional predictive value.

sST2 is a marker of cardiac hypertrophy , fibrosis and myocardial remodeling. It has high application value in the auxiliary diagnosis, prognosis assessment and guidance of the treatment of heart failure. The

study included 747 patients with heart failure. At a median follow-up of 949 days, 231 (30.9%) patients had experienced all-cause death or heart transplantation. Baseline sST2 levels in the overall population were 22.14 (15.04, 34.67) ng/ml.

Patients were divided into case group (n=231) and control group (n=516) according to whether the main clinical endpoint event occurred during hospitalization or follow-up period. The primary clinical endpoint was death from any cause or heart transplantation.

Baseline sST2 levels were higher in the case group compared with the control group.

Multivariate Cox regression analysis results showed that baseline sST2 was an independent predictor of all-cause death or heart transplantation in heart failure patients.

ROC curve analysis results showed that baseline sST2 has a good predictive value for all-cause death or heart transplantation in patients with heart failure at 3 months, 1 year and 3 years.

In 2015, the sST2 international expert consensus recommended 35 ng/ml as the cutoff value for acute heart failure poor prognosis. The optimal cutoff value obtained in this study was 25 ng/ml. Perhaps for the Chinese population, the actual optimal cutoff value of sST2 for heart failure prognostic evaluation is smaller than the current internationally recommended cutoff value.

Multi-factor Cox regression model risk prediction test results show that the predictive value of baseline sST2 for all-cause death or heart transplantation in patients with heart failure is slightly lower than that of baseline NT-proBNP. The combined use of baseline sST2 on the basis of baseline NT-proBNP can predict heart failure. Failure prognosis assessment provides additional predictive value.

The point-of-care test (POCT) method is a point-of-care testing method. Compared with traditional testing methods, it eliminates the need for complicated processing procedures for specimens to be tested in the laboratory. It has the advantages of rapidity, simple use, wide applic - DayDayNews

Reprint: Please mark "Chinese Journal of Circulation"

There are many difficult and complicated cases, and a doctor can only see once in his lifetime

science

Text and photos/Yangcheng Evening News all-media reporter Ouyang Zhiqiang Correspondent Huo Erman Sponsored by China Electronics Society, Intelligent Human-Computer Interaction Expert Committee of China Electronics Society, Aerospace Medical Engineering and Space Biology Professi - DayDayNews

Text and photos/Yangcheng Evening News all-media reporter Ouyang Zhiqiang Correspondent Huo Erman Sponsored by China Electronics Society, Intelligent Human-Computer Interaction Expert Committee of China Electronics Society, Aerospace Medical Engineering and Space Biology Professi

The Second Annual Conference on Intelligent Human-Computer Interaction Technology will open in Foshan on July 8

05/17 1830

"What are humans doing? They discharge so much sewage! The fish are all affected." "Why do humans pursue progress and development? Human beings are very selfish when they only think about themselves." "Why don't humans let other animals manage the earth?" Early in the morning, th - DayDayNews

"What are humans doing? They discharge so much sewage! The fish are all affected." "Why do humans pursue progress and development? Human beings are very selfish when they only think about themselves." "Why don't humans let other animals manage the earth?" Early in the morning, th

Cognition｜What are humans doing?

05/17 1200

pixabay.com State-owned enterprises have stepped out of the "high wall" to promote the scientific and technological achievements they have developed to the society. - DayDayNews

pixabay.com State-owned enterprises have stepped out of the "high wall" to promote the scientific and technological achievements they have developed to the society.

China National Nuclear Corporation joins hands with the national technology market to promote the latest scientific and technological achievements to the society

05/17 1402

Recently, China Forestry Press held a symposium on the theory and technology of grassland ecological restoration and a new book launch of "Main Technical Models of Ecological Restoration of Degraded Grassland". - DayDayNews

Recently, China Forestry Press held a symposium on the theory and technology of grassland ecological restoration and a new book launch of "Main Technical Models of Ecological Restoration of Degraded Grassland".

Commissioned by the National Bureau of Investigation, this major achievement was officially released! It is the first time in the country for an academician to write a preface!

05/17 1924

1. When did cats start to look like this? 2. “This is what an artichoke would look like if you let it bloom.” 3. “A large group of turtles sunbathing on a floating tree trunk” 4. “The passion vine bloomed this morning!” 5. “These two strawberries grew With a pair of happy feet.” - DayDayNews

1. When did cats start to look like this? 2. “This is what an artichoke would look like if you let it bloom.” 3. “A large group of turtles sunbathing on a floating tree trunk” 4. “The passion vine bloomed this morning!” 5. “These two strawberries grew With a pair of happy feet.”

19 photos of natural beauty that will completely mesmerize you

05/17 1539

Text | Science Wormhole animals reproduce through mating, but their pairing forms are diverse and can be divided into relatively rare monogamy (monogamy) and mixed mating. The mixed system also includes polygamy, polyandry, and polyandry. As we all know, animals mate in order to - DayDayNews

Text | Science Wormhole animals reproduce through mating, but their pairing forms are diverse and can be divided into relatively rare monogamy (monogamy) and mixed mating. The mixed system also includes polygamy, polyandry, and polyandry. As we all know, animals mate in order to

"Monogamous" animals, if one partner dies, can they withstand the temptation of mating?

05/17 1119

On July 3, Typhoon Siam made landfall in South China and is pouring rain in many places in the south. Typhoon Airi is moving in the Western Pacific. Today, its center has moved into the East China Sea, bringing refreshing blue sky and white clouds to many places in the Yangtze Ri - DayDayNews

On July 3, Typhoon Siam made landfall in South China and is pouring rain in many places in the south. Typhoon Airi is moving in the Western Pacific. Today, its center has moved into the East China Sea, bringing refreshing blue sky and white clouds to many places in the Yangtze Ri

rare! As hot and high pressure climbs up the Tibetan Plateau, will there be problems with the glaciers? Analysis: Northwest or extreme heat

05/17 1033

As we all know, there are two space stations in Earth orbit today. One is the International Space Station, which has been operating for more than 20 years, and the other is the Chinese Space Station, which has only been operating for one year. The International Space Station is i - DayDayNews

As we all know, there are two space stations in Earth orbit today. One is the International Space Station, which has been operating for more than 20 years, and the other is the Chinese Space Station, which has only been operating for one year. The International Space Station is i

Among the Chinese, Russian and American space station cabins, whose sleeping area is the best? The Tianhe cabin sleeping area is simply a luxury version

05/17 1011

Controlled ion transport within nanochannels is crucial for biological membranes and artificial membrane systems. Covalent organic frameworks (COFs) are emerging crystalline polymer materials with regular and adjustable nanochannels, and have become an ideal material platform for - DayDayNews

Controlled ion transport within nanochannels is crucial for biological membranes and artificial membrane systems. Covalent organic frameworks (COFs) are emerging crystalline polymer materials with regular and adjustable nanochannels, and have become an ideal material platform for

"ACS Nano" from Tianjin University's Wu Hong/Jiang Zhongyi team: charged nanochannels in covalent organic framework membranes achieve efficient ion interception

05/17 1899

NASA Administrator Nielsen has made "wild remarks" in the media again. In a recent interview with Germany's "Bild", he said, "Beware of China occupying the moon." - DayDayNews

NASA Administrator Nielsen has made "wild remarks" in the media again. In a recent interview with Germany's "Bild", he said, "Beware of China occupying the moon."

Afraid? NASA Administrator: Watch out for China occupying the moon! Who wants to bypass the Outer Space Treaty?

05/17 1920