*Reference: Myeongjin Goh et al. Identification of the Underlying Genetic Factors of Skin Aging in a Korean Population. Journal of Cosmetic Science.2021;

2024/04/2717:35:33 science 1806

is a high-tech genetic skin care product that is popular in Europe and America. Is

worth a try?

First of all, we need to understand what "genetic testing" is.

When it comes to genetic testing,

is everyone's thinking like this?

Genetic testing is done for paternity testing , right?

is so complicated that only scientists can understand it...

What exactly is genetic testing?

What is a gene? The

gene is also called the genetic factor . It is a DNA fragment with genetic information and is the structural and functional unit of genetic material in cells. Genes support the basic structure and performance of life, and store all information about life’s race, blood type, pregnancy, growth, apoptosis and other processes.

*Reference: Myeongjin Goh et al. Identification of the Underlying Genetic Factors of Skin Aging in a Korean Population. Journal of Cosmetic Science.2021; - DayDayNews

For example, genes are like the "design drawings" of the human body. They can tell cells to produce different proteins, give instructions to your body, and tell your body how to work.

What is genetic testing?

Genetic testing is a technology that detects DNA through blood, other body fluids or cells. Genetic testing technology can detect mutated genes that cause hereditary diseases.

*Reference: Myeongjin Goh et al. Identification of the Underlying Genetic Factors of Skin Aging in a Korean Population. Journal of Cosmetic Science.2021; - DayDayNews

To put it simply, if the genetic "blueprint" changes, the way of producing proteins will change, which will increase the risk of illness. Genetic testing is to see if you have abnormal genes or disease risks.

*Reference: Myeongjin Goh et al. Identification of the Underlying Genetic Factors of Skin Aging in a Korean Population. Journal of Cosmetic Science.2021; - DayDayNews

Use a cup as an example:

"Wait for the cup to fall, then repair it!"

- This is the hospital;

"Wait for the cup to fall and see how much you can lose!"

- This is insurance;

"Put the cup on Push it in so it doesn't fall off!"

- This is a genetic test.

In real life,

not only can health risks be checked through genetic testing,

can also get a lot of help through genetic testing.

When it comes to beauty and skin care

Why do skin care products recommended by others sting and break out pimples when I use them on my face? I feel like I have dry skin, but why is my face so oily and mottled with the new foundation I bought? Looking at the dazzling array of cosmetics, which one is right for you?

At this time, genetic testing can be used to understand the skin condition more clearly and accurately, so as to take more precise skin care.

When exercising to lose weight

Why is it that while eating the same meal as others, only my own weight keeps increasing? Some people get fat even if they drink water, but some people don't get fat even if they eat too much?

This is also because of genes. There is a gene called "FTO" in the human body, also called obesity gene . People with mutations in the FTO gene have a significantly increased risk of obesity. They prefer to eat high-calorie foods and have higher hunger than ordinary people.

When socializing and drinking

Some people blush when they drink, which is related to the gene " acetaldehyde dehydrogenase ". Some people also call it the "Dukang gene".

Acetaldehyde dehydrogenase is commonly found in Westerners, but some Easterners lack this enzyme. After drinking alcohol, alcohol will cause and acetaldehyde to accumulate in the body. The accumulation of acetaldehyde will cause blood vessels to expand and cause blushing.

Genetic skin care, which is popular in Europe and the United States,

first conducts genetic testing, and then

provides privately customized genetic skin care plans.

Is this high-tech genetic skin care method worth a try?

Scientific experiment

In 2021, Myeongjin Goh, the head of R&D at Amorepacific R&D Center, published in the "Journal of Beauty Science" the relationship between skin aging and other characteristics of Korean women and genes.

*Reference: Myeongjin Goh et al. Identification of the Underlying Genetic Factors of Skin Aging in a Korean Population. Journal of Cosmetic Science.2021; - DayDayNews

Myeongjin Goh's team selected 1,079 Korean women (without skin diseases, average age 40.81) as study subjects, using various tests to measure skin characteristics at P&K Skin Clinical Research Center (Seoul) from January 2019 to November 2019. The device measured five skin characteristics of each person, namely "wrinkles, moisture content, pigmentation, oil content and sensitivity."

*Reference: Myeongjin Goh et al. Identification of the Underlying Genetic Factors of Skin Aging in a Korean Population. Journal of Cosmetic Science.2021; - DayDayNews

uses full gene chip technology to conduct genetic testing of research subjects. The detection sites cover 820,000 genetic sites related to the five major populations of "Europe, America, South Asia, East Asia and Africa". And the genome-wide association analysis (GWAS) was used to determine the chromosomal locations and gene loci of the strongly associated genes of these five skin characteristics (traits). The results are shown in the figure below:

*Reference: Myeongjin Goh et al. Identification of the Underlying Genetic Factors of Skin Aging in a Korean Population. Journal of Cosmetic Science.2021; - DayDayNews

*Reference: Myeongjin Goh et al. Identification of the Underlying Genetic Factors of Skin Aging in a Korean Population. Journal of Cosmetic Science.2021; - DayDayNews

In order to analyze the strongly associated genes analyzed by GWAS and Further precise positioning and identification of sites requires further analysis of associated genes, which are presented as follows using a Manhattan diagram. The gene corresponding to the highest p value in each skin characteristic is the gene site with the highest correlation strength.

*Reference: Myeongjin Goh et al. Identification of the Underlying Genetic Factors of Skin Aging in a Korean Population. Journal of Cosmetic Science.2021; - DayDayNews

Based on the GWAS analysis of skin traits, a total of 32 loci showed significant P values: (shown in the chart above)

Gene loci associated with wrinkles

  • rs117381658 (FCRL5)
  • rs1961184 (REEP3) 9
  • rs1929013 (ADSS)
  • rs7042102 (SPTLC1)

Gene loci associated with moisture content

  • rs9873353
  • rs34567709
  • rs1362404
  • rs7853290
  • rs143938096
  • rs12955989

Gene loci associated with pigmentation

  • rs74653330(OCA2)
  • rs34466224(NCLN)
  • rs11685354(TNS1)
  • rs4653497(CDC42BBPA)
  • rs59784607(HS3ST4)
  • rs76548385(UNCX)

with grease The content of the gene loci associated with

  • rs308971(SYN2)
  • rs9577919(CNDP1)
  • rs8107564(GAS6)
  • rs6490805(INSR)
  • rs151209785(TNFRSF 19)

Gene loci associated with sensitivity

rs7334780rs41308

*Reference: Myeongjin Goh et al. Identification of the Underlying Genetic Factors of Skin Aging in a Korean Population. Journal of Cosmetic Science.2021; - DayDayNews

*Reference:

Myeongjin Goh et al. Identification of the Underlying Genetic Factors of Skin Aging in a Korean Population. Journal of Cosmetic Science.2021;72:63-80.

It can be seen that the

gene is closely related to skin. The

gene determines a person's skin color, texture, sensitivity, etc.,

regulates the synthesis of all functional proteins,

and presents human genetic information to the surface of the skin.

*Reference: Myeongjin Goh et al. Identification of the Underlying Genetic Factors of Skin Aging in a Korean Population. Journal of Cosmetic Science.2021; - DayDayNews

Through skin beauty gene testing,

finds the root cause of skin problems,

analyzes the problems faced by the skin and the aging tendency of the human body,

then chooses products that are more suitable for you,

combines scientific lifestyle and beauty and skin care methods,

defends the skin. question.

Are you excited about this highly efficient and precise genetic skin care method?

?

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