gene editing technology in the agricultural field can accelerate the genetic improvement of crops and is expected to become an important method to solve food problems.
"Journal of Bioengineering": Do you think gene-edited animals/plants are safe as food (meat) or food? If it is safe, why is it safe?
高彩霞: Gene-editing plants and animals uses targeted knockout or modification of their own genomes to change the original undesirable traits and achieve precise breeding. does not require the integration of foreign genes , so I It is believed that gene-editing animals and plants is safe.
"Journal of Bioengineering": Recently, the Japanese and US FDA have approved the sales application of gene-edited tomatoes and gene-edited pigs for food and medical treatment. What impact does this have on related fields?
Gao Caixia: Japan has the same definition of gene-edited animals and plants as the European Union and China. The EU still treats genetically-edited plants and animals in accordance with GMOs, while Japan has adopted a more advanced and scientific approach to the regulation of gene-edited plants and animals. This time Japan’s approval of gene-edited tomatoes on the market shows that Japan will combine gene-edited plants with genetically modified plants. The differential treatment of genetically modified organisms will also provide a good inspiration for the introduction of relevant policies in my country. Scientists in this field hope that my country will also introduce as soon as possible a regulatory policy that is different from genetically modified organisms, but for gene-edited animals and plants, which can increase public trust and promote the sound development of my country's gene editing field.
Well-known scientist and researcher Gao Caixia
"Journal of Bioengineering": Is the current development and application of gene editing technology in my country and abroad at a starting line? If there is a gap, what are the main manifestations?
Gao Caixia: Compared with foreign countries, gene editing technology in my country is basically on the starting line. In a sense, we may still be the leader, such as gene editing technology in my country's two main food crops (rice and wheat). Research is in a leading position in the world. However, if the supervision of gene editing products is not well done in the future,It may cause gene-edited products not to go to the market smoothly and not to be used by consumers, which will inevitably weaken the motivation for scientific research. Existing regulatory policies may become a bottleneck in the application of gene editing technology in my country.
"Journal of Bioengineering": Focusing on the four aspects, what role might gene editing play in my country's agriculture and medicine? What kind of support do scientific researchers need when advancing technology transformation, and what suggestions do you have?
Gao Caixia: The four aspects mainly refer to facing the frontiers of world science and technology, facing the main economic battlefield, facing major national needs, and facing people's lives and health. Gene editing technology itself is a new technology facing the frontiers of world science and technology; the application of gene editing technology in the agricultural field can accelerate the genetic improvement of crops, and is expected to become an important method to solve food problems. The main battlefield is closely related; the application of gene editing technology in the medical field is for people's lives and health. From a scientific point of view, we call on the country to introduce forward-looking gene-edited animal and plant regulatory policies as soon as possible to avoid missing development opportunities. At the same time, it is recommended that researchers in universities and scientific research institutions in my country should strengthen exchanges and cooperation with enterprises when carrying out technology transformation.
"Journal of Bioengineering": There are many stuck neck problems in the field of science and technology in my country that need to be solved urgently. Is there any stuck neck problem in the field of gene editing? If so, what suggestions do you have?
Gao Caixia: In the current environment of Sino-US trade friction, it is recommended that my country should increase its investment in basic research and development and technological advancement of gene editing. On the one hand, we strive to develop new gene editing systems or tools, but the current international competition is fierce and difficult. On the other hand, from the 2020 Nobel Prize in Chemistry awarded to two female scientists who developed genome editing methods, it can be seen that advances in technology and methods play a very important role in the development of science.
Brief introduction of interviewed experts
Gao Caixia, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences researcher, doctoral supervisor, director of the Genome Editing Branch of the Chinese Society of Genetics, member of the 5th Agricultural GMO Safety Committee. He was selected as "Outstanding Technical Talent" and "National Hundreds, Thousands of Talents Project" by Chinese Academy of Sciences .In 2017, he won the National Innovation Award and Tan Jiazhen Life Science Innovation Award. The main research directions are: R&D and application of crop genome editing technology system and molecular biology research on important functional genes of important crops such as wheat. Published many articles in journals such as Science, Nature Biotechnology, Nature Communications, Nature Plants, Nature Protocols, etc.
Original link:
http://news.sciencenet.cn/htmlnews/2021/2/452835.shtm
Extended reading:
Our outstanding alumni and well-known scientist researcher Gao Caixia came to our school for academic studies Exchange
Link:
https://news.gsau.edu.cn/info/1037/36801.htm
On November 12, the Academy of Grass Industry invited Gao Caixia from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Researchers came to our school to hold an academic report on “Genome Editing with Progarammable Nucleases in Crop Plants” for teachers and students. Co-hosted by the college.
listen to the academic report of researcher Gao Caixia
researcher Gao Caixia shared the development history of gene editing technology and gene editing technology in plant breeding with the topic of "Genome Editing with Progarammable Nucleases in Crop Plants",And introduced in detail the related scientific research work done by her research group on plant gene editing in recent years. Nearly a hundred teachers and students from related colleges participated in the report meeting and actively discussed with researcher Gao Caixia on the issues they were interested in. The scene was very lively. Afterwards, some teachers and students of the school took a group photo with researcher Gao Caixia.
Researcher Gao Caixia, graduated from Gansu Agricultural University in 1994, obtained China Agricultural University Ph.D in 1997, from 1997 to 1998, Denmark DLF-Trifolium company engaged in post-doctoral research, 1998-2009 In September, he served as R&D scientist in the scientific research department of DLF-Trifolium, Denmark. He returned to China in September 2009 and worked as a researcher and group leader at the State Key Laboratory of Plant Cell and Chromosome Engineering at the Institute of Genetics and Development of the Chinese Academy of Sciences. He is currently the director of the Institute's Genome Editing Center. In 2010, he was selected as "Outstanding Technical Talent" by Chinese Academy of Sciences . On June 21, 2016, the famous British academic journal " nature " was selected as one of the ten "science stars" in China. In 2017, he won the National Innovation Award and Tan Jiazhen Life Science Innovation Award. In the same year, he was selected into the National Hundreds and Thousands of Talents Project.
Xinhuanet — Lanzhou Evening News: "Nature" magazine selected ten Chinese science stars Gannong University alumni Gao Caixia listed
link:
au https://news.g edu.cn/info/1006/31509.htm
In the early morning of June 21, "Nature" magazine published a news feature article "Sciencestars of China", introducing ten Chinese scientists and their scientific achievements Among them, Gao Caixia, an alumnus of Gansu Agricultural University and a researcher from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences,It was selected for its contribution to the improvement of important crops using gene editing technology.
Gao Caixia, who was the first to use CRISPR-Cas9 gene editing technology on wheat and rice and other crops, is a botanist, researcher, and doctoral supervisor. He received a bachelor's degree from Gansu Agricultural University in 1991. Received a master's degree from Gansu Agricultural University in 1994. Received a Ph.D. from China Agricultural University in 1997. From 1997 to 1998, he was a postdoctoral fellow in the scientific research department of DLF-Trifolium, Denmark. 1998-2009, ResearchScientist, research department of DLF-Trifolium Company, Denmark, project leader. In September 2009, he returned to China and worked as a researcher at the State Key Laboratory of Plant Cell and Chromosome Engineering at the Institute of Genetics and Development of the Chinese Academy of Sciences and the group leader. In 2010, he was selected as the "Outstanding Technical Talent" of the Chinese Academy of Sciences. Its main research fields are the research and application of the crop genome targeted editing technology system, the establishment and application of the crop genetic transformation technology system, and the molecular biology research of important functional genes in wheat.
Wonderful gene editing technology
"A gene editing expert tries to achieve self-worth by improving important crops" as the topic, "Nature" magazine introduced Gao Caixia like this: In the beginning, plants Biologist Gao Caixia is hesitant to use CRISPR–Cas9 technology for gene editing. This technology is sweeping biology laboratories all over the world. Her laboratory has used the old technology to achieve 82 gene mutations, and the idea of switching to the new technology is daunting. (Reporter Ma Wenyan)
news link:
http://www.gs.xinhuanet.com/news/2016-06/22/c_1119088486.htm
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