On August 13, 2020, Harvard University School of Public Health team published an analysis showing that:
new diabetes , history of diabetes or weight loss are all related to pancreatic cancer Related to the increased risk of disease.
Among them, newly diagnosed diabetic patients with a history of diabetes within 4 years, accompanied by weight loss, have a risk of pancreatic cancer that is 3.6 – 6.8 times that of normal people!
Harvard’s team’s analysis is based on two large studies of the Nurses’ Health Study (NHS) and health professionals, the follow-up study (HPFS), more than 150,000 participants’ follow-up data for nearly 30 years .
As a result, a part of the high-risk population of pancreatic cancer was discovered.
Sudden weight loss of more than 3 kg for no reason, the risk of pancreatic cancer soared by 6 times!
research team divided two groups based on the weight loss of newly-onset diabetic patients:
If the patient’s weight suddenly drops to 1 – 8 pounds without interference from external forces, it is related to the risk of pancreatic cancer , Which is 3.61 times that of a normal person.
If you lose more than 8 pounds (3.6 kg), the associated risk will soar 6.75 times!
data also show that even for long-term diabetic patients, a weight loss of more than 8 pounds (3.6 kg) is related to a significant increase in the risk of pancreatic cancer.
The research team also analyzed the medical history of diabetic patients and the weight change during their lifetime.
found that pancreatic cancer patients among long-term diabetic patients are generally relatively obese at the beginning and lose weight before and after cancer.
The initial weight of pancreatic cancer patients with new diabetes is relatively thin, showing a lean-fat-lean change.
"Cancer King" pancreatic cancer is difficult to detect early, and a new high-risk group has been studied
Although early detection and early treatment are the principle of prevention and treatment of cancer, diseases like pancreatic cancer are not easy to find and develop. The cancer rate is not high, and it is definitely not appropriate to screen everyone.
The authoritative recommendation of the US Preventive Services Task Force (USPSTF) clearly opposes routine screening for pancreatic cancer among asymptomatic people.
Screening of the whole population is not feasible, so what about high-risk groups?
There are currently relatively clear high-risk groups for pancreatic cancer, including those with a clear family history, related gene abnormalities, and pancreatic cysts.
performs regular CT, MRI and other examinations on them, which can detect most pancreatic cancers at an early stage, which brings very obvious benefits.
However, among the known high-risk groups, only 15-20% of all patients with pancreatic cancer have been detected, so we have to continue to look for potentially dangerous groups of pancreatic cancer.
has many research findings,Pancreatic cancer and type 2 diabetes may be related. Many patients with pancreatic cancer will experience short-term or persistent symptoms of diabetes.
However, it is not realistic to screen every patient with diabetes.
Because there are more and more people with diabetes, one more condition is needed.
In short, the newly discovered diabetes and recent weight loss population is likely to be a large number and high risk of pancreatic cancer high-risk group, which also contributes to the future designated screening standards.
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