Background: Quality of life (QoL) and sleep in patients with psoriasis are critical to mental, physical and socioeconomic health. However, the exact role of psoriasis clinical subtypes in this regard remains poorly studied.
Objective: The purpose of this study was to investigate differences in impaired quality of life and sleep problems in patients with different clinical subtypes of psoriasis and to assess the impact of pruritus on quality of life.
Methods: This cross-sectional, multicenter study included 295 eligible subjects with a diagnosis of psoriasis, with each patient examined using the same questionnaire. Measures included major subtypes of psoriasis, disease severity, pruritus scores, patients' health-related QoL and incidence of sleep disturbances.
Results: QoL was reduced in most patients regardless of clinical psoriasis subtype, however, QoL was most impaired in patients with erythrodermic psoriasis . Most patients reported sleep disturbance caused by pruritus, although there were no relevant differences between the subgroups analyzed in this aspect of patient health. Pruritus is an important factor in determining quality of life and sleep problems in the study population.
Conclusion: Identifying the most disturbing areas of life and identifying the most bothersome subjective symptoms of psoriasis are critical to focusing on the most relevant treatment targets and achieving treatment success.
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