This article is original to the Translational Medicine Network. Please indicate the source when reprinting. Author: Jevin Introduction: The peaks of the COVID-19 epidemic are rising one after another in various regions. People use many methods to fight against the COVID-19 infect

2025/10/1423:50:35 regimen 1698

This article is an original work of the Translational Medicine Network. Please indicate the source when reprinting.

Author: Jevin

Introduction: The peak of the new crown epidemic is one after another in various regions. People use many methods to fight against the new coronavirus infection, such as salt-steamed oranges, brown sugar, green onion and ginger water, electrolyzed water and canned yellow peach , etc. These empirical methods can alleviate the condition to a certain extent. But there are also situations where drinking a lot of water can lead to water poisoning . Therefore, when facing COVID-19 infection, we must first understand the working principle of non-drug substances to avoid blind actions causing secondary damage to the body.

Clinical trials have shown that vitamin C can improve oxidative imbalance and vascular remodeling caused by different stressors , and weaken endothelial barrier permeability. Therefore, the antioxidant effect of vitamin C and its protective effect on endothelial permeability may play a role during COVID-19 infection, especially during post-infection recovery. Zinc is the second most abundant trace metal in the human body after iron. It has a regulatory effect on the growth and activity of T cells and cytokine storm .

Oral administration of zinc and vitamin C can stimulate the production of antibodies

In 2022, the National University of Singapore research team conducted a randomized clinical trial to observe the impact of zinc and vitamin C on the production of neutralizing antibodies after COVID-19 infection. The study cohort consisted of 422 men, 68 of whom took zinc + vitamin C, 81 took vitamin C, 67 took hydroxychloroquine, 99 took ivermectin, and 107 took povidone-iodine throat spray.

results showed that COVID-19 antibody (IgG) levels were comparable at baseline but increased significantly by day 42. Among them, the zinc + vitamin C group had the highest neutralizing antibody positive conversion rate (46.7%), which was higher than the vitamin C group (19.6%), hydroxychloroquine group (30.8%), ivermectin group (20%) and povidone-iodine group (9.8%). This study is the first to demonstrate the efficacy of oral zinc + vitamin C in stimulating antibody production after COVID-19 infection.

Oral administration of L-arginine and vitamin C can reduce the sequelae of COVID-19

In 2022, Italian and American research teams conducted a national survey in Italy to determine the impact of L-arginine and vitamin C on COVID-19 sequelae. 1,390 COVID-19 patients were evenly divided into two groups and received 30 days of treatment. The first group (n=869) received 1.66g of L-arginine and 500mg of liposomal vitamin C every day, and the second group (n=521) received a multivitamin combination treatment. The study used a modified 0-10 Borg classification ratio scale to score the perceived sequelae of COVID-19 (where 10 means intolerable). The

survey found that patients in the L-arginine + vitamin C treatment group had significantly lower scores than those receiving the multivitamin combination, with no other significant differences between the two groups. This suggests that the combination of L-arginine and vitamin C alleviates the sequelae of COVID-19. The researchers pointed out that endothelial inflammation may be a key mechanism for the impairment of systemic vascular microcirculatory function in long-term COVID-19 patients. This investigation shows for the first time the beneficial effects of the combination of L-arginine and vitamin C in long-term COVID-19.

Research significance

In short, multiple studies have shown that oral zinc + vitamin C is effective in stimulating antibody production after COVID-19 infection. In addition, oral administration of L-arginine + vitamin C can alleviate the sequelae of COVID-19.

Reference:

https://onlinelibrary.wiley.com/doi/10.1002/ctm2.731

Note: This article is intended to introduce the progress of medical research and cannot be used as a reference for treatment plans. If you need health guidance, please go to a regular hospital.

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