Ms. Li is 35 years old this year. She has never been infected during the three years of the epidemic. Recently, after the epidemic was relaxed, Ms. Li was also infected. After she was first infected, Ms. Li was particularly scared. She thought the symptoms would be severe, but the fact was not what she thought.

In the next two days, in addition to fever, Ms. Li also suffered from muscle aches. Although Ms. Li took antipyretics, her body temperature remained at 39°C, and her muscle soreness was unbearable. Ms. Li's pain was worse than any flu she had ever had. For eight hours a night, Ms. Li tossed and turned and woke up several times.

On the third day, Ms. Li no longer had a fever, but began to have symptoms of runny nose, nasal congestion, and sore throat. The symptoms of runny nose and nasal congestion are bearable, but the sore throat makes Ms. Li suffer even more. Although she also took medicine to relieve sore throat, Ms. Li's knife-like pain was not significantly relieved. Apart from being patient, Ms. Li seems to have nothing to do.
Recently, the number of people infected with new crown has increased significantly, and there are many people who have the same experience as Ms. Li. So why is it so painful after getting COVID-19? How can we alleviate this pain? In order to let everyone have more knowledge and understanding of the new crown epidemic, today I will talk to you about the relevant knowledge.
1. How did we get infected with COVID-19?
Currently, the transmission route of COVID-19 is respiratory tract, contact or aerosol . This process sounds simple, but in fact it is much more complicated. In order to facilitate everyone's understanding, here is a brief introduction.
Although our immune system can kill the new coronavirus, it cannot kill it in the first place.

This is because our immune system does not recognize the new coronavirus. Relatively speaking, the new coronavirus is relatively small, and the number that has just entered the human body is not large, so the human body cannot recognize it in time.

The new coronavirus will not be merciful just because the immune system cannot temporarily recognize it. Instead, it takes the opportunity to make massive copies. When the number of new coronaviruses reaches a certain level, the immune system will realize that something is wrong, and then take corresponding measures to deal with it, such as sending immune cells and releasing inflammatory factors.
Since the strength of each person’s immune system is different, and the types of new coronavirus infections are different, the recovery time after infection is not exactly the same for everyone.
Some people have stronger immunity . They can quickly identify the virus and kill it, so these people will recover faster. Some people's immunity can kill most new coronaviruses, so these people's symptoms will be milder. Some people whose immunity is not very good may become seriously infected or even die from it.
2. Why do most people feel uncomfortable after being infected with the new coronavirus?
As for the people infected with the new coronavirus that I have met these days, most of them have muscle pain, and some people have symptoms of headache, low back pain, and sore throat. Many friends develop severe sore throat a few days after being infected with COVID-19. Many people call this sore throat a knife-like pain.

The main reasons why people feel uncomfortable after being infected with COVID-19 can be divided into three points, namely, damage from the virus, inflammatory factors released by the human body, and lactic acid deposition caused by fever.
The new coronavirus is somewhat similar to other viruses in that they cannot live independently without cells. When viruses live in cells, they will cause more or less damage. If the human body's tissues or organs are damaged, it will definitely cause discomfort.
Secondly, when the new coronavirus replicates in large numbers in the human body, the human body will secrete a lot of inflammatory factors in response. Inflammatory factors can kill virus-infected cells, and they can also cause damage to human tissue.
When we have a fever, the body's metabolism will accelerate, and oxygen consumption will also increase relatively.However, lactic acid may be produced during this process due to the enhanced anaerobic metabolism of and . The presence of lactic acid itself can cause muscle soreness.

Among the above three mechanisms that make COVID-19 uncomfortable, inflammatory factors are the most important. There are many kinds of viral infections, such as influenza virus, rhinovirus, respiratory syncytial virus, new coronavirus, etc. After they infect the human body, the symptoms are many similar, such as fever, sore throat, runny nose, muscle pain, etc. The root cause is the inflammatory factors secreted by the human body.
Wherever the inflammatory factors appear, they will cause damage. If it appears in the muscles, it can cause muscle soreness; if it appears in the nasal mucosa, it can cause runny nose and nasal congestion.
3. After being infected with COVID-19, how can you make your symptoms less severe? The reason why
has introduced so much above is mainly to pave the way for this last section. After being infected with COVID-19, in order to make your symptoms less severe, you can take oral non-steroidal anti-inflammatory drugs, which are the antipyretics we usually take.

In addition to reducing fever, antipyretics also have analgesic effects. This is because NSAIDs can inhibit the activity of cyclooxygenase , which mainly catalyzes the conversion of arachidonic acid into prostaglandins. Prostaglandin is an inflammatory factor, and its presence can cause fever, pain, local swelling, etc. NSAIDs can indirectly reduce the synthesis of prostaglandins, thereby relieving symptoms. 
Some friends still feel uncomfortable after taking NSAIDs, and their body temperature is even still higher than 39°C. In this case, you can try oral glucocorticoid . Glucocorticoids have a very powerful anti-inflammatory effect. They can inhibit the damage caused by inflammatory factors to the human body and help non-steroidal anti-inflammatory drugs reduce high temperature. The reason why people feel uncomfortable after being infected with COVID-19 is essentially due to inflammatory factors, which can be considered a state of poisoning. In this case, you can take some glucocorticoids under the guidance of a doctor or professional pharmacist. #True Knowledge New Coordinates#
Many friends are afraid when they hear about glucocorticoids, but in fact there is no need. Short-term use of glucocorticoids can help the human body tide over difficulties and will not cause any harm to the human body. In fact, under normal circumstances, the human body also produces a small amount of glucocorticoids. After being infected with the new coronavirus, there is nothing wrong with using some glucocorticoids appropriately, but it must be done under the guidance of professionals. #Health2022#