This is a phase I clinical drug study for cancer patients with positive CLDN18.2. Registration number CTR20221587. Director Xu Jianming of the General Hospital of the People's Liberation Army of China was the main investigator of the project. After enrollment, the drug was BC008 antibody injection.
Indications: colon cancer , rectal cancer, gastric cancer , pancreatic cancer , ovarian cancer, biliary cancer , etc., not listed here.

BC008 antibody injection is an anti-CLDN18.2 antibody fusion protein independently developed in China. It can specifically target CLDN18.2 molecules on the cell surface, specifically kill CLDN18.2 positive tumor cells, and exert anti-tumor effects.
Also working together to carry out this clinical drug research are Director Zhang Jingdong of Liaoning Provincial Cancer Hospital, Director Yuan Yuan of of Xuzhou Central Hospital, Director Chen Hao of of Lanzhou University Second Hospital, and Director Yao Jun of First Affiliated Hospital of Henan University of Science and Technology. Patients in need can pay attention to :

Drug clinical trial registration and information disclosure platform
exclusion criteria:
- Patients have received any targeted CLDN18 before. 2 Treatment;
- patients with gastric pyloric obstruction or continuous repeated vomiting (vomiting ≥3 times in 24 hours);
- patients with organ transplant history, bone marrow transplant history or stem cell transplant history;
- hepatitis B, hepatitis C , HIV virus infection;
- pregnant or breastfeeding women
patients who need it can pay attention. Please forward it to patients in need if you don’t need it. If you have any questions, please leave a message to ask me anytime.