According to the news published by Southern Metropolis Daily on 2022-12-14 00:07:
On December 13, news about the new crown oral medicines was intensively spread: multiple Internet platforms have or are about to release the sale of two new crown oral medicines, namely Pfizer 's Paxlovid and Henan real creatures' Azfuding .
On December 13, the COVID-19 consultation clinic of the Internet hospital under 1 Pharmaceutical Network began to pre-sale the COVID-19 oral antiviral drug Paxlovid (Nematevir/ritonavir tablets), and the reporter failed to successfully purchase it after repeated attempts. However, a whistleblower told Nandu reporters that he had successfully placed an order at JD Health Internet Hospital at 7 pm on the 13th.
htmlOn 13, the COVID-19 consultation clinic of the Internet hospital under 1 Yao.com began to pre-sale the COVID-19 oral antiviral drug Paxlovid (Nepalmatvir/ritonavir tablets), with a price of 2,980 yuan/box. According to reports, online medicine purchases have not yet been connected to medical insurance, and the price of 2,980 yuan per box is higher than the purchase price of medical insurance for Paxlovid by medical institutions.
Paxlovid What medicine is?
PAXLOVID™ is an oral small molecule novel coronavirus treatment drug used to treat adult patients with mild to moderate novel coronavirus pneumonia (COVID-19) who have progressed to severe high-risk factors, such as patients with severe high-risk factors such as chronic renal disease, diabetes , cardiovascular disease, chronic lung disease, etc. Patients should strictly follow the instructions under the guidance of a doctor, and should pay close attention to the interaction information listed in the instructions during use.
According to clinical trial data previously released by Pfizer, among patients treated with Paxlovid within 3 and 5 days after the onset of symptoms, the hospitalization or mortality rates of patients with COVID-19 were 89% and 88%, respectively, and the viral load of was reduced by 10 times compared with the placebo group. In the overall population of the 28-day study, no deaths were reported in patients receiving the drug, while 10 (1.6%) of those receiving the placebo died.
Nandu reporter noticed that Pfizer official website shows that on February 11, 2022, the State Food and Drug Administration conducted emergency review and approval in accordance with the relevant provisions of the " Drug Administration Law ", and approved the import registration of Pfizer's new coronavirus treatment drug Nematvir tablets/ritonavir tablets (i.e. PAXLOVID™) in accordance with the relevant provisions of the " Drug Administration Law ", and approved the import registration of Pfizer's new coronavirus treatment drug Nematvir tablets/ritonavir tablets (i.e. PAXLOVID™).
htmlOn March 15, the revision points of the "Diagnosis and Treatment Plan for the New Coronavirus Pneumonia (Trial Ninth Edition)" released by the National Health Commission showed that the National Medical Products Administration approved the paxlovid-specific anti-COVID drugs to be written into the latest version of the diagnosis and treatment plan. On March 17, the first batch of 21,200 boxes of Paxlovid entered China and quickly transported to the front line of the nationwide fight against the epidemic, focusing on the treatment of patients with high-risk factors and tendencies in severe cases.
oral medication for the new crown has also brought high income to Pfizer. According to Pfizer's previously released financial report, Paxlovid's total revenue in the first half of 2022 was US$9.6 billion, and Q2 sales exceeded the market's generally expected US$7 billion.
2980 yuan is a monthly expense for an ordinary family. Even if the medical insurance price is 2,300 yuan, it is a lot. If the people in a family are full of money, this is a considerable burden. If you are in rural areas, it will be a two-month expenditure. How many people in rural areas now have medical insurance? Three out of ten are already very productive. Even if you have medical insurance, it is not something that farmers can afford. This is a medicine for high-end people.
The one who belongs to the civilian drug is Azfuding.
"There is news that another new crown oral drug, Azfuding, will be open for online sale of
, was previously launched and then removed from the shelves. On December 13, there are also news that the domestic "new crown special drug, Azfuding," will also be open for online sale. Azfuding will first realize online prescriptions on the Ark Jianke APP and JD Health fever clinic. Prescriptions also require positive nucleic acid tests or positive antigen tests as the basis, and the price is 330 yuan/bottle (1mg*35 tablets).
Regarding Azfuding's online sales issue, the relevant person in charge of Fosun Pharmaceutical responded to Nanduwan Finance and Economics reporters that the relevant specific Internet pharmaceutical sales channels are "still being confirmed". "(the company) has contacted and cooperated with multiple Internet medical platforms to achieve accessibility through multiple channels to further meet the home treatment needs of patients with new coronavirus infection."
The above-mentioned person in charge also said that the current production base of Azfu Ding Tablet manufacturer Real Bio in Pingdingshan, Henan Province has passed the GMP compliance inspection in May this year, and can achieve an annual production capacity of more than 3 billion pieces. At the same time, the drug has completed medical insurance network in 31 provinces across the country and is accelerating the distribution of terminals of hospitals across the country. It has now covered more than 2,000 hospitals across the country.
At present, there are two new crown oral drugs in China approved. In addition to the above-mentioned Paxlovid from Pfizer, it is Azfuding from Real Biologics in Henan.
Azvdine is the first oral small molecule antiviral drug independently developed by my country. It was previously used for the treatment of AIDS . It is a novel nucleoside reverse transcriptase and auxiliary protein Vif inhibitor, and it is also the world's first dual-target innovative anti-AIDS drug. In July 2021, azvdine was launched as a Class 1 innovative drug to treat adult HIV-1 infected patients with high viral load.
But after the outbreak of the new crown, the drug was developed into an anti-COVID-19 drug. On July 25, 2022, the State Food and Drug Administration conducted emergency review and approval, and conditionally approved the registration application for the increase in indications for the treatment of new coronavirus pneumonia. As a result, the drug became the first oral direct antiviral drug developed by a Chinese company to be approved by the State Food and Drug Administration for the treatment of COVID-19. The approval of
Azfuding is undoubtedly of milestone significance. The outside world believes that Azvdin can effectively make up for the shortcomings in the treatment of new coronary pneumonia in China. Since the outbreak of the new crown epidemic, the response methods or means such as medical consumables, diagnostic testing reagents, vaccine, and neutralizing antibodies in China have gradually increased. However, "In terms of therapeutic drugs, in addition to the introduction of Pfizer's Paxlovid, domestic COVID-19 drugs have always been lacking. Azvdin's approval fills the gap in the absence of domestic COVID-19 treatment drugs," said GF Securities .
reporter learned that as of now, Azfu Ding tablets have completed medical insurance listing in 31 provinces, autonomous regions and municipalities across the country. The price of medical insurance listing is 270 yuan/bottle (35 tablets per bottle, 1 mg per tablet). It is accelerating the distribution of terminals of hospitals across the country, and it has now covered more than 2,000 hospitals across the country.
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In addition, both Paxlovid and Azvdin have been included in medical insurance. On March 21 this year, the National Health Insurance Administration issued a notice showing that the Pfizer anti-viral oral drug Nematvir tablets/ritonavir tablets (Paxlovid), which have been included in the "Diagnosis and Treatment Plan for the New Coronavirus Pneumonia (Trial Ninth Edition)" has been included in the medical insurance payment scope.
. According to reports, on August 9, the National Health Commission has issued a notice to include Azfudine tablets in the novel coronavirus pneumonia diagnosis and treatment plan. According to the relevant provisions of basic medical insurance , in order to better ensure the diagnosis and treatment needs, all drugs included in the diagnosis and treatment plan for the new coronavirus can be temporarily included in the medical insurance payment scope. Therefore, when insured patients use this drug, medical insurance fund can be paid according to regulations. ”
The current price of Azfuding’s medical insurance network is 270 yuan per bottle. This price should be easier for the public to accept.
Now, you have to pay for the treatment of the new coronavirus out of your own pocket. It is better not to be infected. If you can avoid infection, you must protect yourself when you go out. Wearing a mask is already standard. I hope everyone is safe and the new coronavirus will become a thing of the past as soon as possible.
