Not long ago, Hu Hongyao, director of the Department of Radiation Intervention at Wuhan University People's Hospital, led a team to successfully perform the first precise interventional surgery for yttrium [Y90] microsphere injection in Hubei Province for a 61-year-old patient wi

Not long ago

Wu University People's Hospital

Directional intervention department director Hu Hongyao leading team

A for a 61-year-old patient with colorectal cancer liver metastasis

Faster implementation of the first case of Hubei Province

yttrium［Y 90] Accurate interventional surgery for microsphere injection

This means that in the face of liver cancer

, especially in the treatment of colorectal cancer liver metastasis

Medical experts have another super "weapon"

So why is yttrium [Y90] interventional treatment of liver cancer

so powerful?

What is the surgery process like?

This issue of experts

Hu Hongyao

How to detect liver cancer in the early stage?

80% of patients found liver cancer

already belonged to the middle and late stage

in the early stage

may have no symptoms

or have mild fatigue, weight loss

and decreased appetite

or have symptoms such as 4

It is easy to ignore

in the early stage, and until the late stage, the skin becomes yellow and tangled

symptoms such as ascites, pain, etc.

checked

to prevent liver cancer. First of all, we need to understand the prone factors of liver cancer:

✦ Hepatitis B, Hepatitis C , Cirrhosis

✦ Drug poisoning , including Aspergillus flavum

If there are the above factors, must check regularly, especially patients with hepatitis .

Every three months to half a year, you have to go to the hospital to check for liver function , , AFP and liver color ultrasound, so that you can diagnose and treat early.

Main factors affecting the survival time of liver cancer patients

❶ Patient's liver and tumor status

includes the basis of liver function and the stage classification of tumors;

❷ Treatment methods for liver cancer

liver cancer progresses very fast, and it must be treated in a timely and effective manner under the premise that the patient is safe and tolerant to hope to control it;

❸ The general situation of patients

includes whether there are any underlying diseases such as heart, brain, lungs and kidneys, body immunity , daily life and emotional reactions, etc.

Why do patients with colorectal cancer have prone to liver metastasis in

?

The blood in the colorectal cavity mainly flows into the liver through the portal vein of . The liver is rich in blood vessels and plays an important role in metabolism and detoxification.

For tumor cells, the liver is rich in blood and provides the necessary conditions for its growth. Colorectal cancer cells arrive at the liver at the first stop after leaving the intestine, so liver metastasis is most likely. What are the treatment methods for liver cancer

?

❶ Surgery treatment

is surgical resection.

❷ Internal medicine treatment

includes radiotherapy and drug treatment.

Radiotherapy in the Oncology Department is mainly external radiation therapy under the radiotherapy machine. Drug treatment includes chemotherapy drugs , targeted drugs, immune drugs and traditional Chinese medicine treatment.

❸Interventional treatment

includes radiofrequency ablation, microwave ablation, and implantation of iodine 125 particles with locally damaged liver metastases; it also includes TACE treatment of perfusion of chemotherapy drugs and embolization materials into liver metastases through hepatic artery , and yttrium 90 selective internal radiation treatment of perfusion of radioactive microspheres.

"yttrium" step is in place

Accurate "ejection" to kill liver tumors

yttrium [Y90] microspheres treatment utilizes the characteristics of liver tumors mainly supplied by the hepatic artery and normal liver parenchyma mainly supplied by the portal vein. By intervening into the hepatic artery cannula, resin microspheres with radionuclide yttrium 90 are injected into the tumor blood vessels, so that yttrium 90 microspheres are distributed into the microvascular network of the tumor, and local radiation is emitted to achieve the purpose of radiation treatment of tumors.

Since the high-energy β ray released by the yttrium 90 microspheres can directly break the DNA double-strand of tumor cells, its close-range radiotherapy effect is significant.

yttrium 90 treatment has the advantages of strong tumor shrinkage, enlargement of excess liver, treatment of rare cancer metastasis and portal vein cancer thrombosis, sensitization chemotherapy and immunotherapy . It is also an important means of preoperative downward phase transformation and pre-liver transplantation treatment. The patient stays in the hospital for a short time after treatment, has small adverse reactions, and can maintain a good quality of life.

indications

Hepatic malignant tumors that cannot be surgically operated or are unwilling to undergo surgical operations (including primary liver cancer and metastatic liver cancer).

contraindications

✅ pregnancy;

✅ portal vein main cancer thrombosis, heavy liver tumor load, insufficient liver function reserve, ascites or other symptoms of liver failure;

✅ patients with previous liver radiation treatment;

✅ Tc-MAA shows non-target gastrointestinal shunt and cannot be corrected or pulmonary shunt ratio 20%.