bloating, stomachache , stomach discomfort...
Common over-the-counter medicines in the home medicine box
For example, digestive-promoting
must have an impression of you?
"Handle pain, stomach bloating, use morbidine "
"Handle pain in digestion, find morbidine help"
morbidine
This is a common medicine called digestion and treatment of stomach pain
Domperidone
is a regular drug in many families.
Recently, it was once again asked to revise the instructions
On October 27, the website of the National Medical Products Administration issued the "Announcement of the National Medical Products Administration on Revising the instructions for Domperidone Preparation (No. 93 of 2022)", among which, the revision of the prescription instructions for domperidone preparations requires "precautions" to include: children under 12 years old (especially infants), adolescents weighing less than 35 kg and adults, and closely monitor adverse reactions when taking the medicine.
Domperidone preparation Over-the-counter drug instructions revision requirements "Precautions" should include: This product is not suitable for children under 12 years old (especially infants), adolescents and adults weighing less than 35 kg.
Domperidone is a gastrointestinal promoter
There are many domestic companies producing
In the past two years,
Domperidone represented by morphine
The application of in clinical practice is becoming more and more stringent
October 28
Deputy Director of the Pharmacy Department of Beijing Hospital Zhang Yatong
Tell Health Times reporter
" Not any patient can use
Only after passing the evaluation under certain conditions will it be used
Now the overall dose of this drug in each hospital is slowly decreasing
It can be said that
mortaline has been from the original common medicine
becomes a drug that is fully evaluated and then used reasonably.
announced that according to the results of the adverse drug reaction evaluation, in order to further ensure the safety of public drug use, the State Food and Drug Administration decided to uniformly revise the instructions for domperidone preparations (including domperidone tablets, domperidone dispersed tablets, domperidone oral disintegration tablets, domperidone capsules, domperidone suspension, domperidone maleate tablets)
As early as August 2016, the Health Times reported that in 2015, the Canadian Ministry of Health even affirmed the risk correlation, saying that domperidone would slightly increase the risk of severe ventricular arrhythmia or sudden cardiac death. Health Canada recommends that medication should be taken at the smallest dose possible in the beginning. In April 2014, the European Medicines Agency published a report recommending that it limit its indications within the entire EU range, and only to relieve nausea and vomiting symptoms, and no longer be used to treat other indications such as bloating or heartburn.
In September 2016, the former State Food and Drug Administration issued the "Announcement on Revising the Instructions for Domperidone Preparation", which revised the instructions for Domperidone over-the-counter and prescription drugs. In the adverse reactions, the content related to heart disease has also been added.
"Dopestidone can be said to be an old drug. This time, it was re-emphasized after re-emphasis. Previously, many clinical evaluations have found that there are risks in children's use, and children should be cautious when using domperidone. This time, the prescription and over-the-counter drugs of morphine have been revised to varying degrees. Over-the-counter drugs limit children to improve the clinical safe use." Zhang Yatong explained that previously FDA pointed out that the serious adverse reactions of domperidone include arrhythmia , cardiac arrest, and sudden death of .
The marketing authorization holders of the above-mentioned drugs shall submit the Drug Review Center of the State Drug Administration or the provincial drug supervision and administration department before January 24, 2023 in accordance with the relevant regulations of the " Drug Registration Management Measures " and other relevant regulations, and in accordance with the revision requirements of domperidone preparations. Drugs produced from the date of filing shall not continue to be used in the original drug instructions.
Remember:
Drugs are drugs after all
is a medicine three-part poison
None of the drugs are suitable for overdose
None of the drugs are suitable for overdose
If the condition has not improved after taking the medicine
Don't delay it. Go to the hospital in time to seek medical treatment
to avoid delaying the disease
Follow the doctor's advice and take medicine symptomatically is the key
